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Articles 1 - 9 of 9
Full-Text Articles in Medicine and Health Sciences
Increasing Inpatient Volume And Efficiency Through Decreasing Readmission Rates At Fox Chase Cancer Center, Courtney Pokallus, Islande Victorin
Increasing Inpatient Volume And Efficiency Through Decreasing Readmission Rates At Fox Chase Cancer Center, Courtney Pokallus, Islande Victorin
Capstone Showcase
This paper outlines the semester long strategic plan created by Islande Victorin and Courtney Pokallus for Fox Chase Cancer Center. This strategic plan includes a background of the organization, SWOT analysis on the organization, identification of potential problems and a gap analysis, a strategic summary, and all outlines and plans for the strategic plan.
The Positive Effects Of Medical Cannabinoids On The Dysregulated Endocannabinoid System In Autism Spectrum Disorder Patients, Caroline J. Reichelderfer
The Positive Effects Of Medical Cannabinoids On The Dysregulated Endocannabinoid System In Autism Spectrum Disorder Patients, Caroline J. Reichelderfer
Capstone Showcase
Autism Spectrum Disorder (ASD) is a developmental disability. The symptoms include a lack of social skills, a need for repetitive patterns of life, difficulty in communication, speaking deficits and numerous other symptoms. While the specific cause is unknown, there is much research being done on mechanisms including dysregulations of the immune system, endocannabinoid system, and overall brain (Nez Govorova 2021, Pol 2021). The Endocannabinoid system is a recently discovered branch of the nervous system composed of endocannabinoids which are produced naturally in the body; lipid-based neurotransmitters that bind to cannabinoid receptors (CBRs) and cannabinoid receptor proteins that are expressed throughout …
High Energy Blue Light Induces Oxidative Stress And Retinal Cell Apoptosis, Jessica Malinsky
High Energy Blue Light Induces Oxidative Stress And Retinal Cell Apoptosis, Jessica Malinsky
Capstone Showcase
Blue light (BL) is a high energy, short wavelength spanning 400 to 500 nm. Found in technological and environmental forms, BL has been shown to induce photochemical damage of the retina by reactive oxygen species (ROS) production. Excess ROS leads to oxidative stress, which disrupts retinal mitochondrial structure and function. As mitochondria amply occupy photoreceptors, they also contribute to oxidative stress due to their selectively significant absorption of BL at 400 to 500 nm. ROS generation that induces oxidative stress subsequently promotes retinal mitochondrial apoptosis. BL filtering and preventative mechanisms have been suggested to improve or repair BL-induced retinal damage, …
Inpatient Management Of An Intravenous Drug User With Tetanus, Nina Paris
Inpatient Management Of An Intravenous Drug User With Tetanus, Nina Paris
Capstone Showcase
Tetanus is rare in the United States now due to the tetanus vaccine but there is still the potential too see patients with tetanus. IV drug users, neonates, and geriatric populations are at an increased risk of developing tetanus. Tetanus is caused by Clostridium tetani, a spore forming and exotoxin releasing anaerobic bacteria. The symptoms of tetanus are caused by the exotoxin tetanospasmin which inhibits the release of inhibitory neurotransmitters, leading to sustained neuronal stimulation. The classic symptoms of tetanus are lockjaw (trismus), neck stiffness, back arching, and fever. Patients can be febrile, tachycardic, tachypneic, and hypertensive on exam. …
Cme: Vitamins, Antidepressants, And The Placebo Effect - How To Help Your Patients, Nicko Inocencio
Cme: Vitamins, Antidepressants, And The Placebo Effect - How To Help Your Patients, Nicko Inocencio
Capstone Showcase
Depression affects roughly 280 million people globally. The disease puts patients at increased risk for stroke, cardiovascular disease, hypertension, and diabetes. The psychosocial causes of depression are well-known, but the biochemical causes are multifactorial. Theories range from homocysteine excess, calcium modulation at the neuron, inflammation, cortisol elevation, and disruption of the HPA axis. At the center, however, is serotonin, norepinephrine, and dopamine. Pharmacologic treatment directly aims at modulation of serotonin, norepinephrine, and dopamine. First-line treatment is a combination of SSRIs/SNRIs with cognitive behavioral therapy. If patients do not see improvement with the above therapy other agents such as bupropion, mirtazapine, …
One In Every Twenty-Six, Rey'na Riggans
One In Every Twenty-Six, Rey'na Riggans
Capstone Showcase
There is a disorder that is rather common within the world and yet is not well known. It is a something that affects one in every twenty-six individuals. It is called epilepsy. Epilepsy is a neurological disorder in which a person to experience bursts of random electrical activity within their brains, these bursts being called "seizures." This article discusses this disorder and goes into detail about the forms of it, procedures that are done to try and help those living with epilepsy, and artwork that is inspired by this disorder.
Managing Neonatal Pain: A Guideline For Non-Neonatal Providers, Kelly Stanton
Managing Neonatal Pain: A Guideline For Non-Neonatal Providers, Kelly Stanton
Capstone Showcase
Neonatal pain, especially in settings outside of the NICU or newborn nursery, is often under-recognized or even unnoticed altogether. Many providers and parents do not know how to recognize when a neonate is in pain and many do not know how to minimize or alleviate this pain effectively. Even when providers know how to assess pain in neonates, they typically assess for acute pain in the presence of chronic pain, or vice-versa. Untreated pain in neonates harms brain development and can lead to behavior defects later in life for these babies. Due to these outcomes, the recognition and effective treatment …
Vitamin D Enhanced Vitamin D Receptor (Vdr) Inhibition Of Nlrp3 Inflammasome Activation Can Attenuate The Development Of Autoimmune Thyroiditis, Alexzon Mandac
Vitamin D Enhanced Vitamin D Receptor (Vdr) Inhibition Of Nlrp3 Inflammasome Activation Can Attenuate The Development Of Autoimmune Thyroiditis, Alexzon Mandac
Capstone Showcase
Autoimmune Thyroiditis (AIT) is a prevalent autoimmune disease affecting approximately 2% of the population. Characterized by the gradual loss of thyroid function through an autoimmune attack on the thyroid gland, the disease manifests symptoms that negatively affect one’s quality of life. The mechanisms behind the disease’s pathophysiology are not fully understood; however, researchers are examining the involvement of the NLRP3 inflammasome in the disease. This thesis will address the question of whether Vitamin D can act as an inhibitor of the NLRP3 inflammasome and attenuate the progression of AIT in mouse model. Current investigations explore the effects of NLRP3 inhibition …
How And Why Do Race And Gender Affect Adhd Diagnosis Levels?, Caitlin N. Bennett
How And Why Do Race And Gender Affect Adhd Diagnosis Levels?, Caitlin N. Bennett
Capstone Showcase
Attention-deficit hyperactivity disorder (ADHD) is a disorder of the brain that impairs one’s daily functioning and focus. Previous research has shown that two groups are disproportionately under-diagnosed: females and Black people. It is important to understand why these groups, and possibly others, are under-diagnosed as those without a diagnosis do not get the treatment that they need. Literature reveals that differences in symptom presentation (inattentive vs. hyperactive), biases in symptom reports, barriers to accessing mental healthcare, and negative stigmas about, and within, certain groups lead to the under-diagnosis of females and Black people. In conclusion the diagnostic criteria of ADHD …