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Full-Text Articles in Medicine and Health Sciences
Reducing The Risk Of Chemotherapy Exposure, Miranda Susman
Reducing The Risk Of Chemotherapy Exposure, Miranda Susman
Symposium of Student Scholars
Concerns about antineoplastic drugs (ANPDs), also known as chemotherapy, began in the early 1970s by the National Institute for Occupational Safety and Health. Although ANPDs are used as a standard treatment for cancer, these drugs are considered hazardous due to their adverse health effects. About eight million healthcare workers are exposed to ANPDs and therefore essential that we continue to educate on ways to reduce the risk of exposure to occupational and home health hazards. The overall purpose of this study is to determine if additional education and use of surface wipe samplings reduce the risk of exposure. A literature …
Designing And Synthesizing A Warhead-Fragment Inhibitory Ligand For Ivyp1 Through Fragment-Based Drug Discovery, Samuel Moore
Designing And Synthesizing A Warhead-Fragment Inhibitory Ligand For Ivyp1 Through Fragment-Based Drug Discovery, Samuel Moore
Symposium of Student Scholars
Fragment-based drug discovery (FBDD) is a powerful tool for developing anticancer and antimicrobial agents. Within this, magnetic resonance spectroscopy (NMR) provides a comprehensive qualitative and quantitative approach to screening and validating weak and robust binders with targeted proteins, making NMR among the most attractive strategies in FBDD. Inhibitor of vertebrate lysozyme (Ivyp1) of P. aeruginosa serves as an excellent target because of its active cellular location and implications in clinical prognosis for cystic fibrosis and immunocompromised patients. This study uses current NMR and biophysical techniques to develop a covalent, fragment-linked warhead inhibitor for Ivyp1 through synthetic methods, warhead linking, and …
The Effects Of Prenatal Patient Education Regarding Epidural Anesthesia, Auburn Merritt
The Effects Of Prenatal Patient Education Regarding Epidural Anesthesia, Auburn Merritt
Symposium of Student Scholars
This project is important because there is a lack of education for prenatal women regarding epidural anesthesia which causes misunderstanding, confusion, a deficit of knowledge, and a lack of support. The purpose of this project is to analyze and suggest the importance of proper education regarding epidural anesthesia. Proper prenatal education causes resolution of misconceptions as well as causes patients to be more satisfied with their pain management during labor. Evidence that I found suggested that after proper education more pregnant women planned to receive epidural anesthesia (Cutajar, 2018). Women preferred detailed education to increase knowledge of the risks and …
Cannabis And Opioids In Chronic Pain Management, Estefan Tsegaye, Clara Kathryn Pollard, Emilie Tate, Justin White, Raphaela Woods
Cannabis And Opioids In Chronic Pain Management, Estefan Tsegaye, Clara Kathryn Pollard, Emilie Tate, Justin White, Raphaela Woods
Symposium of Student Scholars
Background: Many adults suffer from chronic pain. Opioids are commonly prescribed to treat chronic pain, though they can produce adverse side effects and carry the potential for abuse and addiction. The introduction of cannabis in medicine has provided a possible alternative to opioids in chronic pain management. Objective: This systematic literature review aims to synthesize evidence from published studies to answer the following research question in the PICOT format: In adults over the age of 18 with chronic pain (P), how does prescribed cannabis therapy (I) compare with prescribed opioid therapy (C) in affecting perceived pain levels and quality of …
Nursing Education Regarding Take-Home Narcan In Relation To Opioid-Related Deaths, Taylor Birke, Nadia Butt, Bryce Farmer, Sarah Hendrick
Nursing Education Regarding Take-Home Narcan In Relation To Opioid-Related Deaths, Taylor Birke, Nadia Butt, Bryce Farmer, Sarah Hendrick
Symposium of Student Scholars
The opioid epidemic in America has remained a national crisis since 2011 with opioid related deaths continuing to dramatically increase. Naloxone (Narcan) safely reverses the effects of an opioid overdose with little to no side effects. There is a gap in the literature regarding education and stigma-breaking conversations held between addicts and nurses surrounding an opioid overdose. This systematic literature review will examine the effects of nursing education on the acceptance and use of take-home Narcan kits within opioid drug users. Using the Kennesaw State University Library SuperSearch database, we searched for peer-reviewed studies that included one or more of …
Inhibition Of Glutathione Peroxidase, Tosin Masha, Carol Chrestensen, Daniela Tapu, Meleye Mel, Madison Jaames
Inhibition Of Glutathione Peroxidase, Tosin Masha, Carol Chrestensen, Daniela Tapu, Meleye Mel, Madison Jaames
Symposium of Student Scholars
Glutathione peroxidase (GPx) is an intracellular antioxidant enzyme that mediates the amount of hydrogen peroxide present in cells. Through this activity, GPx aids in the regulation of cellular processes that use hydrogen peroxide, including growth and proliferation. It may be desirable to inhibit GPx in certain diseased states, e.g. cancer, where GPx is over expressed. The Tapu lab is making N-heterocyclic compounds that have shown efficiency inhibiting thioredoxin reductase, which is another selenocysteine containing enzyme. Our aim is to test similar compounds to see if they have the ability to inhibit GPx. In order to test these compounds, we have …
Evaluating Volatile Organic Compounds For Contact-Independent Antagonism Of Pseudogymnoascus Destructans
Symposium of Student Scholars
White-nose syndrome (WNS), a disease caused by the fungus Pseudogymnoascus destructans, is responsible for the extensive mortality of bats in the United States. In an effort to develop tools to reduce bat mortality attributed to WNS, an in vitro experiment was conducted to quantify the inhibitory effects of select volatile organic compounds (VOCs) as well as explore potential synergistic activities. The experiment involved exposing mycelial plugs of P. destructans to various concentrations of B23 as well as B23 and decanal together at equimolar ratios. Measurements of the plugs were taken over the course of the 13 day experiment allowing …