Medicine and Health Sciences Commons^™

Insulin Signaling In Osteocytes In Bone Development, Vivin Karthik

Costas T. Lambrew Research Retreat 2021

Hypothesis: IRS1/2 signaling is necessary for osteocyte development and function

Control Of Perivascular Adipose Tissue Differentiation During Cardiovascular Disease, Katie Stieber

Costas T. Lambrew Research Retreat 2021

Hypothesis: Lower BMI will correlate with lower RAB27a expression

Determinants Of Private Well Water Testing In Maine, Jenny Carwile, Shravanthi M. Seshasayee, Kritika Anand, Abby F. Fleisch

Costas T. Lambrew Research Retreat 2021

Objectives: Describe sociodemographic characteristics associated with ever testing well water using data from the 2014-2017 Maine Behavioral Risk Factor Surveillance System (BRFSS) (n= 12,152).

Inhibiting Fatty Acid Binding Protein Family Members Decreases Multiple Myeloma Cell Proliferation Through Effecting The Myc Pathway, Mariah Farrell, Heather Fairfield, Anastasia D'Amico, Carolyne Falank, Connor Murphy, Michaela Reagan

Costas T. Lambrew Research Retreat 2021

FABP inhibition leads to increased survival of myeloma bearing mice and decreased cell growth by inhibiting MYC signaling.

Institutional Experience With Primary Interventional Radiology Sclerotherapy For Lymphatic Malformation, Obiyo Osuchukwu, Brenton Reading, Charlene Dekonenko, Wendy Jo Svetanoff, Jeff Thekkekara, Douglas C. Rivard, Charles L. Snyder, Tolulope A. Oyetunji

Costas T. Lambrew Research Retreat 2021

Interventional Radiology Sclerotherapy is effective for treatment of primary and recurrent lymphatic malformations

Plasma Concentrations Of Per- And Polyfluoroalkyl Substances And Body Composition From Mid-Childhood To Early Adolescence, Jaclyn Janis, Sheryl Rifas-Shiman, Shravanthi M. Seshasayee, Clifford J Rosen, Abby F Fleisch, Sharon Sagiv, Emily Oken

Costas T. Lambrew Research Retreat 2021

BACKGROUND

• Per- and polyfluoroalkyl substances (PFAS) may alter body composition by lowering anabolic hormones and increasing inflammation.

Prior studies have found positive, inverse, and null associations of PFAS concentrations with adiposity among children and adolescents.

Few studies have examined associations of PFAS concentrations with changes in body composition longitudinally.

No study has examined the association of PFAS plasma concentrations with lean mass.

The Effect Of High Fat Diet On Marrow Adipocytes From C57bl/6j (B6) Mice, Gisela Pachón-­Peña, Clifford J. Rosen, Samantha Costa

Costas T. Lambrew Research Retreat 2021

In mice models, the administration of a high fat diet (HFD) is an accelerating factor for metabolic syndrome, impaired glucose tolerance, and early type 2 diabetes mellitus (T2DM) (1)

Preventive Healthcare Services Receipt And Primary Care Provider Utilization Among People Who Inject Drugs, E K. Nenninger, Kinna Thakarar

Costas T. Lambrew Research Retreat 2021

Introduction:

People who inject drugs (PWID) face barriers to accessing primary care providers (PCPs) and preventive services, but are at increased risk for preventable infections

Preventive services can be accessed through PCPs, or while hospitalized or at community organizations like syringe service programs (SSPs)

The Introduction Of A Multimodal Clinical Pathway For Outpatient Total Knee Arthroplasty In The Era Of Covid-19, D Bunch, R Mountjoy, G Korsunsky, A Rana, C Sturgeon

Costas T. Lambrew Research Retreat 2021

The combination of a short acting spinal and muscle-sparing regional blocks, including adductor canal and iPACK blocks, can allow for successful outpatient total knee arthroplasty.

Ketamine Infusions For Post-Cesarean Pain In Patients With Opioid Use Disorder, Talitha Budi, Johanna Cobb, Wendy Craig, Heather Turcotte, Janelle Richard, Aurora Quaye

Costas T. Lambrew Research Retreat 2021

Discussion:

• Opioid consumption may be reduced during ketamine infusion without significant side effects

• Further investigation planned with a prospective, randomized, double-blind, placebo-controlled trial.

Improving The Care Of Patients With Cirrhosis At Mmc, Lesley B. Gordon, Elizabeth Herrle, Matt Buttarazzi, Monica Thim, Jenna S. Ptaschinski, Victoria Molina, Natalie Channell

Costas T. Lambrew Research Retreat 2021

Purpose: Improve the rate and timeliness of paracenteses for patients with decompensated cirrhosis.

Exploring Ob/Gyn Provider Knowledge, Practice And Confidence Levels Before And After Aces Training, Nadi Nina Kaonga, Alexandra Turnbull, Paula Vokey, Julia Brock

Costas T. Lambrew Research Retreat 2021

Trauma-informed training on ACEs improves provider confidence on screening and treating their prenatal patients.

Standardized Ekg Curriculum, Michael Ellerman, Jon Nichols, Sanjeev Francis

Costas T. Lambrew Research Retreat 2021

Goal: To study the effect of a standardized EKG curriculum on competency of interpreting common EKGs among internal medicine residents

Boot Camp Translation: Community Engaged Research Process Evaluation, Emma Daybranch, Kerri Barton, Brendan Schauffler, Lisbeth Wierda, Neil Korsen

Costas T. Lambrew Research Retreat 2021

The BCT process was first developed by the High Plains Research Network and its Community Advisory Council in rural Colorado. Between 2004 and 2015 the BCT process was used 31 times across the U.S. on a broad range of topics.

Anterior-Based Muscle Sparing Approach For Total Hip Arthroplasty, Callahan M. Sturgeon, George M. Babikian, Brian J. Mcgrory, Adam J. Rana

Costas T. Lambrew Research Retreat 2021

A high value, high quality and low cost surgery: a 7.5 year single-center, retrospective case series

Communicating About Covid-19: Strategies For Promoting Risk-Reducing Behaviors On Facebook, Liz Scharnetzki, Nikki Jarvais, Elizabeth Rintz, Leo Waterston, David Pied, Paul Han

Costas T. Lambrew Research Retreat 2021

Introduction- Controlling the COVID-19 pandemic requires effective public health communication strategies that can promote risk-reducing behaviors despite scientific uncertainties about their effectiveness. The current project developed and tested different theory-based communication strategies for generating public interest in COVID-19 risk-reducing behaviors. • Assessed the efficacy of two novel message frames – destigmatizing and uncertainty normalizing - relative to existing strategies

Impact Of Bowel Management Guidelines On Documentation And Patient Outcomes In The Intensive Care Unit, Alana Trottier, Paul Blakeslee, Kristiina Hyrkas

Costas T. Lambrew Research Retreat 2021

Introduction

• Bowel management (BM) is an inadvertently overlooked aspect of patient care for critically ill patients who have complex, immediate life-threatening health issues.

• Bowel dysfunction is common with the reported incidence of diarrhea between 3.3%-78% and constipation between 20-83%

• Studies suggest that BM guidelines can standardize care, improve documentation, and impact patient outcomes

• Use of BM guidelines has remained low, probably influenced by clinicians’ resistance to change, resulting in small to moderate improvements and difficulties sustaining new practices

• We anticipated that sustained changes require recognizing clinicians’ current practice, integrating modifications into existing workflow, and engaging …

An Evaluation Of The Rollout Of Aunt Bertha, A Community-Centered Directory, Across The Mainehealth Network, Samantha Dinsdale, Lisbeth Wierda, Kerri Barton, Ellen Freedman

Costas T. Lambrew Research Retreat 2021

Remote interviews were conducted with community-based organizations across Maine to gain insight to their perspective of Aunt Bertha’s use and potential.

Examining The Relationship Between Markers Of Emergency Department Crowding And Physician Wellbeing, Jessica Dibiase, Tania D. Strout, Samir Haydar, Karla Hyde, Elizabeth Hamilton, Christine Hein

Costas T. Lambrew Research Retreat 2021

Objectives-

Explore changes to EP wellbeing over time.

Evaluate the relationships between markers of ED crowding and boarding and EP wellbeing

Development Of Maine Ongoing Outreach Simulation Education (Moose), A Novel Telesimulation Program, To Improve Neonatal Resuscitation In A Rural Community Hospital, Allison Zanno, Misty Melendi, Micheline Chipman, Jeffrey Holmes, Alexa Craig, Samantha Piro, Anna Gilbert, Sarah Gabrielson, Leah Mallory, Anya Culter, Mary Ottolini

Costas T. Lambrew Research Retreat 2021

Objective- To implement monthly neonatal resuscitation telesimulation team training sessions in a rural community hospital delivery room that is feasible, sustainable, and replicable at other sites.

A Period Seroprevalence (Sars-Cov-2) Survey In Mhccn Cancer Healthcare Workers (Hcws) Providing Patient Care During The Height Of The Outbreak: A Registry Study (Initial Progress), Jill Prescott, Caroline Knight, Erin Hobart, Jamie Saunders, Kimberly Caron, Sandra Neptune, Patty Brown, Lisa Lemire, Anne Breggia, Susan L. Guierin-Staples, Lee Lucas, Paul Han, Rachit Kumar, Robert Carlson, Scot Remick

Costas T. Lambrew Research Retreat 2021

Introduction: There is little information on the basic epidemiologic and serologic profile(s) of the novel SARSCoV- 2 coronavirus especially in HCWs employed in rural settings. We embarked on a period seroprevalence study in the MaineHealth Cancer Network (MHCCN) to document Covid-19 exposure in our rural cancer care workforce. Our fundamental hypothesis is that despite implementing procedures to safeguard patients and the use of appropriate PPE in the care of known source patients/PUIs in both the inpatient and outpatient cancer care settings a small, but not insignificant number of cancer care providers (hereafter referred to as cancer HCWs) will have evidence …

Leveraging Spiritual Care Resources To Reduce The Number Of Behavioral Events On An Acute And Intermediate Medical-Surgical Unit, Natasha Bartlett, Tia Jamir, Sally Langerak, Heather Weidemann

Costas T. Lambrew Research Retreat 2021

In 2018, R4/AVU an acute and intermediate care medical unit at Maine Medical Center (MMC), had a high level of distressing behavioral events (Code Grays) and staff stress.

Impact Of A Primary Care Clinical Pharmacist On The Management Of Hepatitis C Viral Infection, Sierra Ferreiira, Adam Normandin, Linh Gagnon, Corinn Martineau

Costas T. Lambrew Research Retreat 2021

Interprofessional care including a pharmacist demonstrates a positive trend towards increasing access to care and improving adherence to Hepatitis C management in a primary care setting.

Ideographic Modeling And Data Visualization Of Sleep, Affect, And Psychotic Symptoms: A Case Example, D M. Weiss, E Aslinger, W L. Cook, K A. Johnson, K M. Elacqua, R I. Mesholam-Gately, K A. Woodberry

Costas T. Lambrew Research Retreat 2021

Background:

1. Psychotic disorders are heterogeneous.

2. Current diagnostic categorizations are unable to capture individuals’ unique symptom experiences.

3. Newly-developed ideographic analyses and data visualization tools may be useful in assessing individuals’ symptom experiences and stimulating data informed care.

Resilience Of Regional Hospital Nursing Staff Working During The Covid-19 Pandemic Measured By The Connor-Davidson Resilience Scale, Jill Petzel Baer

Costas T. Lambrew Research Retreat 2021

Low resilience is widespread in nursing staff during the COVID-19 pandemic

Investigation Of The Relationship Between Obesity, Weight Cycling, And Tumor Progression In Murine Myeloma Models, Heather Fairfield, Catherine R. Marinac, Mariah Farrell, Brenda M. Birmann, Michaela R. Reagan

Costas T. Lambrew Research Retreat 2021

We investigated this relationship in two murine myeloma models with a high fat diet (HFD) to induce obesity, and a diet cycling (DC) regimen to model weight cycling.

Perceptions Of Self-Efficacy And Experiences Of Mindfulness On Pain And Anxiety In Patients Undergoing A Colorectal Surgery: A Prospective Mixed Methods Study, Rebecca Brown, Julie Fitzgibbons, Rachel Farrington

Costas T. Lambrew Research Retreat 2021

Introduction

• Pain and anxiety have a physiological response on the body.

• Increased heart rate, respiratory rate and blood pressure can lead to complications, and thus longer hospitalization along with decreased patient satisfaction.

Facilitators And Barriers To Accessing Harm Reduction Services In A Rural State, Kinna Thakarar, Michael Kohut, Deb Burris, Hannah Loeb, Rebecca Hutchinson, Kathleen Fairfield

Costas T. Lambrew Research Retreat 2021

INTRODUCTION

• The impact of social distancing policies during the COVID-19 pandemic on people who inject drugs (PWID) is not known.

• We aimed to describe the impact of the pandemic on PWID access to harm reduction services in Maine

Novel Roles Of Mir-199b In Regulating Fat And Bone Metabolism, Aldona Karaczyn, Victoria Demambro, Jennifer Daruszka, Patrizia Roy, Clifford Rosen, Calvin Vary

Costas T. Lambrew Research Retreat 2021

Public Health Problem:

The incidence of obesity has reached epidemic proportions worldwide and has contributed to an increase in the risk of numerous chronic disorders-type 2 diabetes-liver pathologies, dyslipidemia, and cardiovascular diseases.

Obesity can have negative effects on bone remodeling-reduced mineral density-osteoporosis

Imbalance between food intake and energy expenditure-obesity-accumulation of fat mass and energy storage in white adipose tissue (WAT).

Parent Experience Of Hie And Hypothermia: A Call For Trauma Informed Care, Anna Sagaser, Betsy Pilon, Annie Goeller, Monica Lemmon, Alexa Craig

Costas T. Lambrew Research Retreat 2021

Objective:

To assess parents’ experience of communication with the medical team and involvement with their infant during HIE treatment.