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Yale Medicine Thesis Digital Library

Theses/Dissertations

1986

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Full-Text Articles in Medicine and Health Sciences

Gene Expression During The Latent And Replicative States Of The Epstein-Barr Virus, Ronald John Weigel May 1986

Gene Expression During The Latent And Replicative States Of The Epstein-Barr Virus, Ronald John Weigel

Yale Medicine Thesis Digital Library

Gene expression of the Epstein-Barr virus (EBV) was examined during the latent and lytic viral cycles. During latency the virus expresses two small RNAs (EBERs) and the EB nuclear antigen (EBNA). A gene encoding one peptide of the EBNA complex was mapped using S1 nuclease analysis. EBNA peptide is encoded by a 2028 base exon contained within the EBV Bam HI K fragment; the 3' end of this exon occurs 30 bp after the polyadenylation signal AATAAA and the 5' end occurs within a splice acceptor site. The latent state was disrupted experimentally by treatment with phorbol ester or superinfection …


Characterization Of Calmodulin From C₆ Astrocytoma Cells And Rat Cerebrum, Jay Alan Gates Jan 1986

Characterization Of Calmodulin From C₆ Astrocytoma Cells And Rat Cerebrum, Jay Alan Gates

Yale Medicine Thesis Digital Library

No abstract provided.