Medicine and Health Sciences Commons^™

Joint Modelling In Liver Transplantation, Elizabeth Renouf

Vivian C. McAlister

Reuse Of Liver Grafts Following Brain Death Of The Initial Recipient, Hideaki Tanaka, Vivian C. Mcalister, Mark Levstik, Cameron Ghent, Paul Marotta, Douglas Quan, William Wall

Vivian C. McAlister

AIM: To determine if there is a reasonable prospect of success of a re-use liver transplantation.

METHODS: We systematically searched for reports of liver graft re-use using electronic searches of PubMed and Web of Knowledge. We performed hand searches of references lists of articles reporting re-use of grafts.

RESULTS:A systematic review of the literature reveals 28 liver transplantations using previously transplanted grafts. First and second recipients ranged in age from 4 to 72 years and 29 to 62 years respectively. Liver disease in the first recipient was varied including 5 (18%) patients with fulminant liver failure who died subsequently of …

A Queuing Model To Address Waiting Time Inconsistency In Solid-Organ Transplantation, David A. Stanford, Jung Min Lee, Natasha Chandok, Vivian C. Mcalister

Vivian C. McAlister

Organ transplantation is a vital therapy for the treatment of many patients. Due to blood compatibility rules, there has been a pattern in many jurisdictions for differing organ types where recipients of blood type O experience longer waiting times than those of other blood types, partly due to crosstransplantation of too many O organs to compatible donors of other blood types. In response to this, a recent development in some jurisdictions is a change in the rules to insist upon ABO-identical transplantation. The literature review herein enables us to conclude that unrestricted cross-transplantation has not achieved equity of access across …

Composite Tissue Allotransplantation To Treat Veterans With Complex Amputation Injuries, Vivian C. Mcalister, Ray Kao, Brian Church, Markus Besemann, Rob Stiegelmar

Vivian C. McAlister

Amputee rehabilitation may be limited by complexity of injury (e.g. bilateral arm amputation), associated injury (e.g. colostomy) or by the level of amputation (e.g. high above knee). Our objective is to assess the potential for composite tissue allotransplantation (CTA) to overcome these barriers. Medical literature was searched and programs were surveyed regarding the current status of CTA. Results CTA remains an experimental reconstructive option that involves a large collaborative (physiatry, orthopaedic, plastic and transplant surgeons). Limb transplantation has evolved out of limb reimplantation surgery and organ transplantation. Approximately 10 programs world wide, with almost a decade of experience, report 90% …

Do Older Patients Utilize Excess Health Care Resources After Liver Transplantation?, Neil Shankar, Mamoon Albashir, Paul Marotta, William Wall, Vivian C. Mcalister, Natasha Chandok

Vivian C. McAlister

INTRODUCTION: Liver transplantation is a highly effective treatment for end-stage liver disease. However, there is debate over the practice of liver transplantation in older recipients (age ≥ 60 years) given the relative shortage of donor grafts, worse post-transplantation survival, and concern that that older patients may utilize excess resources postoperatively, thus threatening the economic feasibility of the procedure.

AIM: To determine if patients ≥ 60 years of age utilize more health resources following liver transplantation compared with younger patients.

MATERIAL AND METHODS: Consecutive adult patients who underwent primary liver transplantation (n = 208) at a single center were studied over …

Waiting For Liver Transplantation In Canada: Waitlist History 2000--2004 And Sensitivity Analysis For The Future., David Stanford, Elizabeth Renouf, Vivian C. Mcalister

Vivian C. McAlister

Living-Donor Liver Transplantation: Surgical Techniques And Innovations By Tanaka, Koichi Inomata, Yukihiro Kaihara, Santoshi, Vivian C. Mcalister

Vivian C. McAlister

Living-donor liver transplantation combines the techniques of hepatic resection and transplantation. The principal difference between living donation of liver and resection is the absolute requirement in the former to maintain the integrity of the liver on each side of the dividing line. To do this, the surgeon must retain the vascular supply and drainage of both sides throughout the dissection, up to the moment of graft removal. In this book, Tanaka and colleagues take us through the surgery in a manner that is at once detailed and exciting, through the generous use of magnificent electronic photography.

Circulating Endothelial Cells After Transplantation, A. B. Salazar, Vivian C. Mcalister, R. Gupta, A. S. Macdonald

Vivian C. McAlister

Fate of renal allografts that survive vascular rejection To measure the outcome for grafts that survive early vascular rejection, we reassessed 411 biopsy samples taken from 260 patients in the first month after transplantation. Patients were separated into four classifications, according to Banff 1997 criteria: vascular rejection (36 patients); acute cellular rejection ([ACR] 30); no rejection (194); and 974 recipients from the same era who did not undergo biopsy. Other than graft histology, the groups did not differ for known adverse prognostic factors. The mean follow-up period was 6·03 years (SD 4·7). Graft survival is presented in the table. The …

Sirolimus-Tacrolimus Combination Immunosuppression., Vivian C. Mcalister, Zu-Hua Gao, Kevork Peltekian, Javier Domingues, Kamran Mahalati, Allan S. Macdonald

Vivian C. McAlister

A series of 32 recipients of liver, kidney, or pancreas transplants who were treated with sirolimus and low-dose tacrolimus experienced a low rate of rejection and excellent graft function without drug-related toxic effects.

The Effect Of Silica Inhibition Of Macrophage On Renal Allograft Rejection, Carman A. Giacomantonio

Vivian C. McAlister

The Role Of Rejection In Aortic Valve Allograft Failure, Ahmad Moustapha

Vivian C. McAlister