Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- GLUT1 (2)
- Glucose uptake (2)
- Acute regulation (1)
- Animal ethics (1)
- Animals and religion (1)
-
- Decision-making (1)
- Depression (1)
- Disease-modifying anti-rheumatic drugs (1)
- Environmentalism (1)
- Food ethics (1)
- HCLE cells (1)
- Health disparity (1)
- Hydroxylamine (1)
- L929 cells (1)
- L929 fibroblast cells (1)
- Meat-eating (1)
- Nitroxyl (1)
- Rheumatoid arthritis (1)
- Risk perception (1)
- Standard American diet (1)
Articles 1 - 5 of 5
Full-Text Articles in Medicine and Health Sciences
Silencing Synuclein At The Synapse With Plk2, Brendan D. Looyenga, Patrik Brundin
Silencing Synuclein At The Synapse With Plk2, Brendan D. Looyenga, Patrik Brundin
University Faculty Publications and Creative Works
No abstract provided.
Knowing The Standard American Diet By Its Fruits: Is Unrestrained Omnivorism Spiritually Beneficial?, Matthew C. Halteman
Knowing The Standard American Diet By Its Fruits: Is Unrestrained Omnivorism Spiritually Beneficial?, Matthew C. Halteman
University Faculty Publications and Creative Works
This essay aims to challenge the standard [North] American diet's (SAD) default status in church and among North American Christians generally. It attempts to allay some common concerns about the suitability of food ethics as a topic for serious Christian discernment, and argues that SAD is not spiritually beneficial, drawing support from five traditional sources for Christian moral deliberation, including and especially general revelation and discernment of the fruits of the spirit.
Hydroxylamine Acutely Activates Glucose Uptake In L929 Fibroblast Cells, Larry L. Louters, Jared P. Scripture, David P. Kuipers, Stephen M. Gunnink
Hydroxylamine Acutely Activates Glucose Uptake In L929 Fibroblast Cells, Larry L. Louters, Jared P. Scripture, David P. Kuipers, Stephen M. Gunnink
University Faculty Publications and Creative Works
Nitroxyl (HNO) has a unique, but varied, set of biological properties including beneficial effects on cardiac contractility and stimulation of glucose uptake by GLUT1. These biological effects are largely initiated by HNO's reaction with cysteine residues of key proteins. The intracellular production of HNO has not yet been demonstrated, but the small molecule, hydroxylamine (HA), has been suggested as possible intracellular source. We examined the effects of this molecule on glucose uptake in L929 fibroblast cells. HA activates glucose uptake from 2 to 5-fold within two minutes. Prior treatment with thiol-active compounds, such as iodoacetamide (IA), cinnamaldehyde (CA), or phenylarsine …
Differential Regulation Of Glut1 Activity In Human Corneal Limbal Epithelial Cells And Fibroblasts, David P. Kuipers, Jared P. Scripture, Stephen M. Gunnink, Matthew J. Salie
Differential Regulation Of Glut1 Activity In Human Corneal Limbal Epithelial Cells And Fibroblasts, David P. Kuipers, Jared P. Scripture, Stephen M. Gunnink, Matthew J. Salie
University Faculty Publications and Creative Works
The corneal epithelial tissue is a layer of rapidly growing cells that are highly glycolytic and express GLUT1 as the major glucose transporter. It has been shown that GLUT1 in L929 fibroblast cells and other cell lines can be acutely activated by a variety agents. However, the acute regulation of glucose uptake in corneal cells has not been systematically investigated. Therefore, we examined glucose uptake in an immortalized human corneal-limbal epithelial (HCLE) cell line and compared it to glucose uptake in L929 fibroblast cells, a cell line where glucose uptake has been well characterized. We report that the expression of …
Influence Of Patient Characteristics On Perceived Risks And Willingness To Take A Proposed Anti-Rheumatic Drug, Richard W. Martin, Kelsey Mccallops, Andrew J. Head, Aaron T. Eggebeen
Influence Of Patient Characteristics On Perceived Risks And Willingness To Take A Proposed Anti-Rheumatic Drug, Richard W. Martin, Kelsey Mccallops, Andrew J. Head, Aaron T. Eggebeen
University Faculty Publications and Creative Works
The causes of the underutilization of disease modifying anti-rheumatic drugs (DMARDS) for rheumatoid arthritis (RA) are not fully known, but may in part, relate to individual patient factors including risk perception. Our objective was to identify the determinants of risk perception (RP) in RA patients and predictors of their willingness to take a proposed DMARD (DMARD willingness). Methods. A cross-sectional mail survey of RA patients in a community rheumatology practice. Patients were presented a hypothetical decision scenario where they were asked to consider switching DMARDs. They evaluated how risky the proposed medication was and how likely they would be to …