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USF Tampa Graduate Theses and Dissertations

2018

Affinity Chromatography

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Partial Characterization Of Plasmodium Falciparum Protein Kinase Abck2 (Pfabck2), Muhammad Khalid Jun 2018

Partial Characterization Of Plasmodium Falciparum Protein Kinase Abck2 (Pfabck2), Muhammad Khalid

USF Tampa Graduate Theses and Dissertations

Malaria is a major threat to the public health worldwide as it is affecting populations in tropical and subtropical areas globally. Among those populations are around 40% of pregnant women and children who are susceptible to this disease. Plasmodium falciparum is the most lethal agent that causes malaria in human. Currently, there is drug resistance against antimalarial drugs in parasite against treatment of malaria infections, it is essential to search for new drug targets in order to find cure and alleviate suffering of human population.

There are approximately 100 protein kinases in P. falciparum that are involved in phosphorylation of …