Medicine and Health Sciences Commons^™

Studies Of Amino Acid Mutations In Drug Resistance Of The Smo Protein, Eunice Wintona

UNO Student Research and Creative Activity Fair

Smoothened receptor (SMO) is a protein that in humans, is encoded by the SMO gene. A systemic mutation in its binding pocket helps predict the sensitivity of mutant proteins to different drugs. Known as a GPCR-like receptor, it is a component of the hedgehog signaling pathway; a pathway involved in body patterning and the regulation of adult stem cells. An uncontrolled or inappropriate activation of the Hedgehog pathway drives tumor progression in cancers and a number of birth defects. To achieve these goals, the molecular modeling software MOE was used to build small molecules and drug molecules like Vismodegib and …

Addressing Hydrocephaly In Viet Nam: A Plausible Prevention And Intervention Medical Support Program Proposal, Chelle Mcintyre-Brewer

UNO Student Research and Creative Activity Fair

Families affected by hydrocephalus in Viet Nam have few options for sustainable treatment for a myriad of reasons, primarily centering on barriers to care prevalent to minority, underserved, and economically disadvantaged populations. High morbidity and abandonment rates often result from these circumstances. An interdisciplinary examination of the factors contributing to causal concerns reveals unique cultural considerations, language and literacy barriers, ethnic and geographic differences, as well as economic and governmental issues greatly impacting patient outcome for this condition. The author contends that a program that addresses sociological concerns, along with the medical treatment of the patient, proffers the opportunity for …

Cam Impingement In A Collegiate Male Soccer Player With Bilateral Arthroscopic Labral Repair, Nayun Ahn

UNO Student Research and Creative Activity Fair

Cam impingement in a collegiate male soccer player with the bilateral arthroscopic labral repair.

To demonstrate cam impingement and recurrent cam deformity caused by femoroacetabular impingement after bilateral arthroscopic labral repair in a collegiate male soccer player. Cam impingement is caused by deformities of the femoral head. The deformity is generated due to overuse and high shear stress on the femoral head leading to restricted hip ROM by grinding the articular cartilage. It is typically detected in young, active male populations playing high-impact sports. In this case, one NCAA Division 1 soccer midfielder reported the recurrent cam impingement after he …

Developing A Footswitch Device To Assess The Likelihood Of Falls In At-Risk Populations, Arash Mohammadzadeh Gonabadi

UNO Student Research and Creative Activity Fair

Falls are one of the major cause of injuries, reduced functioning and even mortality in older adults. Most of the falls occur during walking, so considering the mechanics of gait during walking can provide insight to identify the risk of fall in this population. A component of walking mechanics associated with falling in the elderly is gait variability (i.e. the inherent natural fluctuations between strides). Healthy states are associated with an optimal level of movement variability reflecting the adaptability of the underlying control system, while pathological gait can be either too regular, or periodic, or too random and disordered. In …

A Delayed Diagnosis Of Tarsometatarsal Ligament (Lisfranc) Sprain In A Female College Soccer Athlete And Foot Rehabilitation, Boyoung Park

UNO Student Research and Creative Activity Fair

A Delayed Diagnosis of Tarsometatarsal Ligament (Lisfranc) Sprain in a Female College Soccer Athlete and Foot Rehabilitation

Park B*, Nicola M*, Wilkins S*: *University of Nebraska at Omaha, Omaha, NE

Objective: To emphasize the importance of the correct treatment protocol and the proper rehabilitation exercises based on the patient’s injury condition and healing process. Background: A 22-year-old female division I soccer athlete underwent tarsometatarsal ligament repair to stabilize midfoot. The patient started feeling pain in the dorsal aspect of her left 1st and 2nd metatarsals at the beginning of the season, however, she reported no specific mechanism of injury …

Venous Thoracic Outlet Syndrome With Paget-Schroetter’S Syndrome In A Male Collegiate Baseball Player, Jaeho Jang

UNO Student Research and Creative Activity Fair

A NCAA Division I baseball middle infielder complained of discomfort in his right upper extremity. He reported no specific mechanism of injury. He had a history of right elbow fracture at age eight with joint displacement. However, no other previous injury to his upper extremity was reported. He did not feel any pain or abnormal sensations while exercising, but noted some discomfort in the right arm, shoulder and pectoral muscles afterward. The evaluating athletic trainer also noted obvious swelling and discoloration of the right arm, bilaterally different temperature, decreased radial pulse, and positive Roo’s and Adson’s Tests. The venous duplex …

Subthreshold Vibration Does Not Affect Walking Performance Of Transtibial Amputees, Charles Sloan

UNO Student Research and Creative Activity Fair

Ian Sloan , Jenny A. Kent, Shane R. Wurdeman, Adam L. Jacobsen, Kota Z. Takahashi, Nicholas Stergiou. Subthreshold vibration does not affect walking performance of transtibial amputees. Objective: To test the hypothesis that adding subthreshold vibrations to the thigh of the affected limb on amputees would allow for better control of the prosthesis. Setting: Biomechanics Research Building at UNO. Participants: 14 transtibial amputees (age range, 33-72y). Intervention: Applying subthreshold vibrations to thigh of affected limb for three different conditions; white noise signal, pink noise signal, and none. Outcome Measures: Step length, step width, and step …

Acute Subdural Hematoma In A High School Football Player Requiring Emergent Decompressive Craniecromy, Christine Center

UNO Student Research and Creative Activity Fair

The purpose of this report is to present the case of a high school football player that was injured in a game causing an acute subdural hematoma (SDH). A SDH is a potential life-threatening arterial vessel bleed in the brain, causing increased intracranial pressure. The intervention used to treat the athlete was an emergent decompressive craniectomy. The uniqueness of the case is due to both rare pathology and treatment method used. The athlete had a positive outcome due to prompt on-field assessment, and advanced surgical treatments. Certified Athletic Trainers (ATC) should know how to recognize symptoms of traumatic brain injury, …

Dynamic Stability Association With Cost Of Transport Is Different In Patients With Copd Compared To Healthy Controls, Farahnaz Fallah Tafti

UNO Student Research and Creative Activity Fair

Patients with chronic obstructive pulmonary disease (COPD), suffer from deficits in their functional performance besides their lung disease. In this situation, increased muscle activity is needed to provide safe walking patterns, stability while walking. This increase in muscle activity leads to increased metabolic cost, i.e., using more oxygen to complete the task. The main objective of this study is to investigate the relationship between walking stability and metabolic cost in patients with COPD in comparison with age-matched controls. Seventeen patients with COPD and 23 healthy controls walked on a treadmill at three different speeds: preferred, fast (+20% preferred) and slow …

Can The Scale-Free Networks, Improve The Prediction Of Pertussis Infection Rates?, Kimia Ameri

UNO Student Research and Creative Activity Fair

Whooping cough is a highly contagious disease with randomness pattern of infection. Outbreaks of whooping cough have increased over the past few years and has drawn the attention of health care providers. Understanding the spread mechanisms of contagious disease is very important and timely. Extension of contagious disease depends on many complicated factors including pathogen and host environment, exposed population and their activities. In this work, we try to find best prediction for the exposed population. A new SEIR model based on network (NB-SEIR) proposed to improve the accuracy of prediction for number of infected individuals. For this purpose, the …

Overall Wellness Of First Generation College Student-Athletes, Shane Warehime

UNO Student Research and Creative Activity Fair

The present study examined the overall wellness of first-generation student-athletes (FGSA) in comparison to non-first generation student-athletes (non-FGSA),first-generation college students (FGCS), and non-first generation college students (non-FGCS). Overall wellness was assessed using the Five-Factor WellnessInventory. Non-FGSA scored significantly higher than non-FGCS in overall wellness and life satisfaction. Non-FGSA and FGSA scored significantly higher than non-FGCS and FGCS in the physical self subscale (i.e., diet, exercise). In sum, athletics may play an important role in the wellness of student-athletes, which could be enough to mitigate any challenges that first-generation college students face.

Follow My Voice: The Future Of Phr Authentication, Jeanette M. Rose, Ryan Schuetzler, John R. Windle, Ann L. Fruhling

UNO Student Research and Creative Activity Fair

The current electronic personal health record (PHR) has low patient adoption [1]. Increasing use and adoption of the PHR will improve patient-centered care. Users often have difficulty remembering passwords or share them, giving multiple people access to one account.

Utilizing biometrics for authentication is becoming more common in our daily lives – think of the fingerprint sensor on a smartphone or retina scanners at high security corporations. The quickly evolving technology that runs our lives calls for incorporating biometric authentication into more systems. Using biometric authentication can ensure that passwords would not need to be remembered and that only the …

Impact Of Real World Environments On Movement Variability, Matt Harrison

UNO Student Research and Creative Activity Fair

Osteoarthritis; OA for short, is the most common form of arthritis and is one of the leading causes of disability. OA is the progressive wearing down of the cartilage covering bones and joints. For those with end stage knee OA, a total knee arthroplasty, or replacement, is the standard treatment with more than 700,000 TKA’s performed annually. While pain is improved in general, the functional performance and activity levels of the joint often do not return to those of healthy individuals. To understand the long-term consequences of poor function post-TKA, we need data that characterizes an individual’s real-world movement and …

Supervised Walking Exercise Therapy Improves Gait Biomechanics In Patients With Peripheral Artery Disease, Anthony Arellano, Sara A. Myers, Iraklis Pipinos, Ben Senderling, Molly Schieber, Jason Johanning, Cassidy Berlin, Holly Despiegelaere

UNO Student Research and Creative Activity Fair

Peripheral artery disease (PAD) is commonly caused by atherosclerotic build-up of plaque within the peripheral arteries, affecting the blood flow to the legs. The most common presentation of PAD is intermittent claudication; a condition in which when the patient walks the metabolic demands of the lower limbs exceed the limited supply of blood, causing exercise- induced discomfort and decreased walking ability. Walking exercise is the first line of treatment in patients with claudication with the best results achieved in patients undergoing supervised exercise therapy for at least three months. Supervised walking exercise results in increased maximum walking distances comparable to …