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Full-Text Articles in Medicine and Health Sciences
Effects Of Resveratrol On The Alterations Of Cavernosal Enos And Lox-1 Expression In The Hypercholesterolemic Condition: A Preliminary Study, Ozan Bozkurt, Aykut Kefi̇, Ömer Demi̇r, Nergi̇s Murat, Sedef Gi̇dener, Ahmet Adi̇l Esen
Effects Of Resveratrol On The Alterations Of Cavernosal Enos And Lox-1 Expression In The Hypercholesterolemic Condition: A Preliminary Study, Ozan Bozkurt, Aykut Kefi̇, Ömer Demi̇r, Nergi̇s Murat, Sedef Gi̇dener, Ahmet Adi̇l Esen
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the effects of resveratrol on the alterations of cavernosal eNOS and LOX-1 mRNA expression in the hypercholesterolemic condition. Materials and methods: Twenty-one New Zealand white male rabbits were separated into three groups. Rabbits were fed with a normal dietary intake for the control group and a 2% cholesterol diet for the hypercholesterolemia and resveratrol groups for 6 weeks. Resveratrol 4 mg/kg daily was administered for the resveratrol group. Cavernosal LOX-1 and eNOS mRNA expressions were determined with real-time RT-PCR in all groups. The statistical analysis was performed with the Kruskal?Wallis and …
Effects Of Resveratrol And Cigarette Smoking Onbone Healing: Histomorphometric Evaluation, Özge Kolkesen Şahi̇n, Müge Çina Aksoy, Mustafa Ci̇hat Avunduk
Effects Of Resveratrol And Cigarette Smoking Onbone Healing: Histomorphometric Evaluation, Özge Kolkesen Şahi̇n, Müge Çina Aksoy, Mustafa Ci̇hat Avunduk
Turkish Journal of Medical Sciences
Background/aim: The aim of the present study is to investigate the effects of cigarette smoke (CS) and simultaneous application of resveratrol on bone healing histomorphometrically and to evaluate the effects of resveratrol on negative effects of CS. Materials and methods: For 4 weeks, Sprague Dawley rats were exposed to cigarette smoke at the equivalent of 6 cigarettes per day. After this period, monocortical defects were created in femurs by a trephine bur on day 28. Starting from the day of defect creation to the 28th postoperative day, rats were given 20 mg/kg body weight resveratrol. Histomorphometric examination of the number …
Effect Of Resveratrol On Resistin And Apelin Gene Expressions In Adipose Tissue Of Diabetic Rats, Sadegh Zarei, Massoud Saidijam, Jamshid Karimi, Reza Yadegarazari, Azam Rezaei Farimani, Solmazsaadat Hosseini-Zijood, Mohammad Taghi Goodarzi
Effect Of Resveratrol On Resistin And Apelin Gene Expressions In Adipose Tissue Of Diabetic Rats, Sadegh Zarei, Massoud Saidijam, Jamshid Karimi, Reza Yadegarazari, Azam Rezaei Farimani, Solmazsaadat Hosseini-Zijood, Mohammad Taghi Goodarzi
Turkish Journal of Medical Sciences
Background/aim: Adipose tissue plays a major role in glucose homeostasis. Dietary antioxidants such as resveratrol (RSV) may offer some protection against the early stage of diabetes mellitus and the development of complications. The present study investigated the effects of RSV on biochemical parameters and resistin and apelin gene expressions in adipose tissue of rats with type 2 diabetes. Materials and methods: Diabetes was induced using a single dose of streptozotocin + nicotinamide. Three groups of diabetic rats were treated with different doses of RSV (1, 5, and 10 mg/kg body weight per day). Oxidative status, serum biochemical parameters, insulin, and …