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Full-Text Articles in Medicine and Health Sciences
The Paraoxonase 1 (Pon1) Gene Polymorphisms In Coronary Artery Disease In The Southeastern Turkish Population, Abdussemet Hazar, Fuat Di̇lmeç, Mustafa Göz, Aydemi̇r Koçarslan, Mehmet Sali̇h Aydin, Abbas Heval Demi̇rkol
The Paraoxonase 1 (Pon1) Gene Polymorphisms In Coronary Artery Disease In The Southeastern Turkish Population, Abdussemet Hazar, Fuat Di̇lmeç, Mustafa Göz, Aydemi̇r Koçarslan, Mehmet Sali̇h Aydin, Abbas Heval Demi̇rkol
Turkish Journal of Medical Sciences
To investigate the association between the paraoxonase 1 (PON1) c.163T>A and c.575A>G polymorphisms and coronary artery disease (CAD), and whether specific polymorphisms in the PON1 gene are associated with CAD in the southeastern Turkish population. Many different genetic and clinical factors have been identified as causes or contributors to atherosclerosis. Complex diseases such as CAD, hypertension, and diabetes are usually caused by an individual’s susceptibility to various genes, environmental factors, and the interactions between them. The PON1 enzyme has been implicated in the pathogenesis of atherosclerosis and CAD. Materials and methods: Enrolled in this study were 61 patients …
Glutamate Dehydrogenase And Triose-Phosphate-Isomerase Coding Genes For Detection And Genetic Characterization Of Giardia Lamblia In Human Feces By Pcr And Pcr-Rflp*, Kareem Hatam Nahavandi, Esmaeel Fallah, Mohammad Asgharzadeh, Nasrin Mirsamadi, Behroz Mahdavipour
Glutamate Dehydrogenase And Triose-Phosphate-Isomerase Coding Genes For Detection And Genetic Characterization Of Giardia Lamblia In Human Feces By Pcr And Pcr-Rflp*, Kareem Hatam Nahavandi, Esmaeel Fallah, Mohammad Asgharzadeh, Nasrin Mirsamadi, Behroz Mahdavipour
Turkish Journal of Medical Sciences
The purpose of this study was comparison of the glutamate dehydrogenase (gdh) and triose phosphate isomerase (tpi) genes for detection and genetic characterization of Giardia lamblia (G. lamblia) in human stool by polymerase chain reaction (PCR) and PCR-restriction fragment length polymorphism (RFLP). Our assay was specific and distinguished between G. lamblia assemblages A and B. Materials and methods: Among the 325 stool samples obtained from patients with acute gastroenteritis hospitalized in the Pediatric Hospital and infected humans referred to the Tabriz Reference Laboratory (TRL), 34 Giardia-positive stool samples were identified by conventional techniques. Two assays-PCR and PCR-RFLP-targeting the tpi and …