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Turkish Journal of Medical Sciences

Journal

2001

AgNOR

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Full-Text Articles in Medicine and Health Sciences

Hormonal Profile And Agnor Values In Pituitary Adenomas, Sema Hücümenoğlu, Handan Kaya, Esi̇n Koti̇loğlu, Gülben Erdem, Evri̇m Demi̇ray, Gülsün Eki̇ci̇oğlu Jan 2001

Hormonal Profile And Agnor Values In Pituitary Adenomas, Sema Hücümenoğlu, Handan Kaya, Esi̇n Koti̇loğlu, Gülben Erdem, Evri̇m Demi̇ray, Gülsün Eki̇ci̇oğlu

Turkish Journal of Medical Sciences

Nucleolar organizer regions (NORs) are chromosomal segments in which ribosomal RNA is encoded. The AgNOR technique, which reveals these regions, has rarely been used in diagnosis and preceding the prognosis of pituitary adenoma. The purpose of this study was to evaluate the correlation of hormonal profile with the AgNOR counts, and the correlation of recurrence with the AgNOR counts and to determine the concordance between the evaluations of two different observers. This study included 33 patients wıth pituitary adenoma. The slides were stained with hematoxylin and eosin, silver colloid method for NORs and immunohistochemistry for the hormone expressions. Consistency was …