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Medicine and Health Sciences Commons

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Theses and Dissertations

2019

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Full-Text Articles in Medicine and Health Sciences

Assessing Egyptians' Knowledge, Perceptions, And Attitudes Towards Generic Medicines, Radwa Ahmed Elmoneer Oct 2019

Assessing Egyptians' Knowledge, Perceptions, And Attitudes Towards Generic Medicines, Radwa Ahmed Elmoneer

Theses and Dissertations

Medicines are vital component of any health system worldwide, and ensuring accessibility of affordable, effective and safe medications is a critical public policy goal considered by every country. Egypt has, recently, faced aggravated challenges in ensuring the availability of medications countrywide. In response, the Egyptian government has adopted a number of pharmaceutical policies and interventions, mainly, targeting the supply side of the market. Promoting the use of generic medicines is an effective policy intervention that addresses the demand side, a highly recommended intervention given other countries’ experiences. As the main users of medications, patients are a crucial source of knowledge …


Mining For Specialized Metabolism Genes In Red Sea Brine Pool Prokaryotic Metagenomes For Antibacterial And Anticancer Activities, Laila Ziko Feb 2019

Mining For Specialized Metabolism Genes In Red Sea Brine Pool Prokaryotic Metagenomes For Antibacterial And Anticancer Activities, Laila Ziko

Theses and Dissertations

Antibiotic and anticancer drug resistance are current global health threats, thus new antibiotics and anticancer agents are required to treat the strains and cancers that are currently untreatable with the available drug spectrum. One way to search for new chemotherapeutics is to search nature, particularly metagenomes of un-cultured microbial communities. A subset of specialized metabolites (SMs) produced by microbes confer activities of pharmaceutical importance, such as antibacterial and anticancer effects, and are coded by specialized metabolism gene clusters (SMGCs) in the organisms’ genomes. We aimed to search for SMGCs in the metagenomes of Red Sea brine microbial communities by employing …