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Full-Text Articles in Medicine and Health Sciences
Expression Of Mir-29a And Ifn-Γ In Pigs Vaccinated With Modified Live Prrs Vaccine, Sunaree Nantakhruea, Nuntawan Aunjangwang, Orawan Limsivilai, Win Surachetpong
Expression Of Mir-29a And Ifn-Γ In Pigs Vaccinated With Modified Live Prrs Vaccine, Sunaree Nantakhruea, Nuntawan Aunjangwang, Orawan Limsivilai, Win Surachetpong
The Thai Journal of Veterinary Medicine
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the important RNA viruses that affects swine production worldwide. To better improve vaccine efficacy, understanding the molecular mechanisms and viral-host interaction is important to increase the knowledge of vaccine response. The objective of this study was to investigate the expression levels of miR-29a and IFN-γ in pigs that received modified live PRRSV vaccine. The study revealed that both miR-29a and IFN-γ transcript levels increased in vivo early, at day 3 post vaccination, whereas levels of miR-29a and IFN-γ mRNA were not different at day 7 post vaccination. Our study is …
Antiviral Activity Of Thymus Vulgaris And Nepeta Cataria Hydrosols Against Porcine Reproductive And Respiratory Syndrome Virus, Kraijak Kaewprom, Yu-Hsin Chen, Chuen-Fu Lin, Ming-Tang Chiou, Chao-Nan Lin
Antiviral Activity Of Thymus Vulgaris And Nepeta Cataria Hydrosols Against Porcine Reproductive And Respiratory Syndrome Virus, Kraijak Kaewprom, Yu-Hsin Chen, Chuen-Fu Lin, Ming-Tang Chiou, Chao-Nan Lin
The Thai Journal of Veterinary Medicine
Porcine reproductive and respiratory syndrome (PRRS) is characterized by reproductive failure of sows and respiratory problems of nursery and growing pigs. Current management strategies mainly focus on preventing PRRS virus (PRRSV) infection through vaccination. However, the currently available modified live vaccines are not sufficient to eradicate the virus and do not provide complete immunity from infection. In search of agents that may be proven clinically effective against North American PRRSV (NA-PRRSV or US-PRRSV) infection, 42 natural herb hydrosols were purified and subjected to screening of their antiviral activity against two US-PRRSV strains in MARC-145 cells. Based on results obtained from …