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The Thai Journal of Veterinary Medicine

2017

Antiarrhythmic drug

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Effects Of Ivabradine On Left Ventricular Function In Dogs With Congestive Heart Failure, Sajika Sri-Ngam, Soontaree Petchdee Mar 2017

Effects Of Ivabradine On Left Ventricular Function In Dogs With Congestive Heart Failure, Sajika Sri-Ngam, Soontaree Petchdee

The Thai Journal of Veterinary Medicine

Ivabradine is an essential drug administered in current standard therapy for human heart failure and is expected to be beneficial to congestive heart failure dog. Ivabradine is a selective If Channel inhibitor. It reduces cardiac pacemaker activity and slows heart rate. There are a few reports of ivabradine in veterinary applications. The aim of this study was to investigate the effects of ivabradine on left ventricular function in dogs with congestive heart failure. Thirteen client-owned dogs with systolic and/or diastolic heart failure were included in this study. The dogs were assigned to two groups: (i) the active control group, given …