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Articles 1 - 4 of 4
Full-Text Articles in Medicine and Health Sciences
A Literature Review On Thermogenesis As A Prospective Obesity Treatment, Kellyn Sheppard
A Literature Review On Thermogenesis As A Prospective Obesity Treatment, Kellyn Sheppard
Senior Honors Theses
The disease of obesity has quickly escalated from an epidemic to a worldwide pandemic in the last few decades, and viable treatment methods are being investigated with urgency. One such treatment method is increased induction of the thermogenesis pathway that is active in brown adipose tissue. This pathway is typically activated in mammals when they are exposed to cold temperatures for extended periods of time but can also be induced exogenously. Thermogenesis is a metabolically inefficient process that occurs in the mitochondria of a cell, meaning it uses substrate energy without generating ATP. The inefficiency of this process allows excess …
The Effects Of Obesity On Human Ambulation: A Lower Joint Analysis, Laura Gilbert
The Effects Of Obesity On Human Ambulation: A Lower Joint Analysis, Laura Gilbert
Senior Honors Theses
The effects of obesity on the body are complex and numerous especially when combining the effects on an already multi-faceted and multi-systems action such as human ambulation. This study summarizes a wide range of research performed, which investigated the effects of obesity on human ambulation. The effects are broken down into categories including osteoarthritis, replacement surgery, center of mass, stepping cycle, muscular activation, and specifics of the hip, knee and ankle joints as well as foot changes. The overwhelming majority of studies have found obesity to negatively impact ambulation by shifting center of mass (COM), increasing metabolic cost, decreasing cadence …
Childhood Obesity And Familial Hypercholesterolemia: Genetic Diseases That Contribute To Cardiovascular Disease, Alyssa Caudle
Childhood Obesity And Familial Hypercholesterolemia: Genetic Diseases That Contribute To Cardiovascular Disease, Alyssa Caudle
Senior Honors Theses
Childhood obesity occurs as the result of an imbalance between caloric intake and energy expenditure. Genetic risk factors for obesity have become an area of research due to its permanency. Mutated genes such as Fat Mass and Obesity Associated (FTO), Leptin (LEP), Leptin Receptor (LEPR), Melanocortin 4 Receptor (MC4R), Adiponectin C1Q and Collagen Domain Containing (ADIPOQ), Proprotein Convertase Subtilisin/Kexin Type 1 (PCSK1), and Peroxisome Proliferator-Activated Receptor Gamma (PPARG) all contribute to the development of childhood obesity. In the presence of high cholesterol caused by obesity, the genetic condition known as familial hypercholesterolemia is exacerbated. Familial hypercholesterolemia is caused by a …
Women’S Understanding Of The Effects Of Obesity On Pregnancy, Rachel A. Daniel
Women’S Understanding Of The Effects Of Obesity On Pregnancy, Rachel A. Daniel
Senior Honors Theses
Obesity is a serious issue and is becoming a significant problem around the world. Obesity in general causes and complicates many health problems. As obesity increases in the population at large, the incidence of obesity in pregnancy continues to increase. Obesity during pregnancy has been linked in numerous studies to multiple complications, and the issues and risks have been clearly established. Also becoming pregnant or having multiple pregnancies increases the likelihood of developing obesity. Obese women of childbearing age many times do not even know these risks exist. There is a need to educate these women before they become pregnant, …