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Full-Text Articles in Medicine and Health Sciences
Reduction And Recovery Of Self-Sustained Muscle Activity After Fatiguing Plantar Flexor Contractions, Anthony J. Blazevich, Ricardo N. O. Mesquita, Ronei S. Pinto, Timothy Pulverenti, Sébastien Ratel
Reduction And Recovery Of Self-Sustained Muscle Activity After Fatiguing Plantar Flexor Contractions, Anthony J. Blazevich, Ricardo N. O. Mesquita, Ronei S. Pinto, Timothy Pulverenti, Sébastien Ratel
Research outputs 2022 to 2026
Purpose: Persistent inward calcium and sodium currents (PICs) are crucial for initiation and maintenance of motoneuron firing, and thus muscular force. However, there is a lack of data describing the effects of fatiguing exercise on PIC activity in humans. We simultaneously applied tendon vibration and neuromuscular electrical stimulation (VibStim) before and after fatiguing exercise. VibStim induces self-sustained muscle activity that is proposed to result from PIC activation. Methods: Twelve men performed 5-s maximal isometric plantar flexor contractions (MVC) with 5-s rests until joint torque was reduced to 70%MVC. VibStim trials consisted of five 2-s trains of neuromuscular electrical stimulation (20 …
Fatigue Behaviour Of Load-Bearing Polymeric Bone Scaffolds: A Review, Hamed Bakhtiari, Alireza Nouri, Mehrdad Khakbiz, Majid Tolouei-Rad
Fatigue Behaviour Of Load-Bearing Polymeric Bone Scaffolds: A Review, Hamed Bakhtiari, Alireza Nouri, Mehrdad Khakbiz, Majid Tolouei-Rad
Research outputs 2022 to 2026
Bone scaffolds play a crucial role in bone tissue engineering by providing mechanical support for the growth of new tissue while enduring static and fatigue loads. Although polymers possess favourable characteristics such as adjustable degradation rate, tissue-compatible stiffness, ease of fabrication, and low toxicity, their relatively low mechanical strength has limited their use in load-bearing applications. While numerous studies have focused on assessing the static strength of polymeric scaffolds, little research has been conducted on their fatigue properties. The current review presents a comprehensive study on the fatigue behaviour of polymeric bone scaffolds. The fatigue failure in polymeric scaffolds is …
Hybrid Delivery Of Cluster-Set Resistance Training For Individuals Previously Treated For Lung Cancer: The Results Of A Single-Arm Feasibility Trial, C. M. Fairman, O. L. Owens, Kristina L. Kendall, J. Steele, A. R. Schumpp, Christopher Latella, M. T. Jones, L. Marcotte, J. M. Dawson, C. M. J. Peddle-Mcintyre, K. K. Mcdonnell
Hybrid Delivery Of Cluster-Set Resistance Training For Individuals Previously Treated For Lung Cancer: The Results Of A Single-Arm Feasibility Trial, C. M. Fairman, O. L. Owens, Kristina L. Kendall, J. Steele, A. R. Schumpp, Christopher Latella, M. T. Jones, L. Marcotte, J. M. Dawson, C. M. J. Peddle-Mcintyre, K. K. Mcdonnell
Research outputs 2022 to 2026
Background: Individuals with non-small cell lung cancer (NSCLC) are burdened by long-lasting symptoms (e.g., dyspnea and fatigue) post-treatment. These symptoms often reduce physical activity levels and increase the risk of functional decline. Though we have previously proposed cluster-set resistance training to mitigate symptom burden in lung cancer, there is currently no data on the feasibility or acceptability of this mode of exercise in cancer. Therefore, the purpose of this study was to investigate the feasibility and acceptability of a hybrid-delivery home-based cluster-set resistance training program in individuals with NSCLC stages I–III (i.e., early stage). Methods: This study aimed to recruit …
Fatigue Does Not Increase Limb Asymmetry Or Induce Proximal Joint Power Shift In Habitual, Multi-Speed Runners, Shayne Vial, Jodie Cochrane Wilkie, Mitchell Turner, Anthony J. Blazevich
Fatigue Does Not Increase Limb Asymmetry Or Induce Proximal Joint Power Shift In Habitual, Multi-Speed Runners, Shayne Vial, Jodie Cochrane Wilkie, Mitchell Turner, Anthony J. Blazevich
Research outputs 2022 to 2026
During prolonged jogging, joint moment and work tend to decrease in the distal (ankle) joint but increase at proximal (hip/knee) joints as performance fatigue manifests, and such adaptations might be expected to occur in sprinting. Fatigue is also thought to increase inter-limb asymmetries, which is speculated to influence injury risk. However, the effects of fatigue on sprint running gait have been incompletely studied, so these hypotheses remain untested. Using statistical parametric mapping, we compared 3-D kinematics and ground reaction force production between the dominant (DL) and non-dominant (NDL) legs of 13 soccer players during both non-fatigued and fatigued sprint running. …
Pilot Feasibility And Acceptability Study Evaluating Use Of Group Cbt-I In Improving Sleep And Fatigue In Older Adults, Aisling Smyth, Shehnas Alam, Sabine Pangerl
Pilot Feasibility And Acceptability Study Evaluating Use Of Group Cbt-I In Improving Sleep And Fatigue In Older Adults, Aisling Smyth, Shehnas Alam, Sabine Pangerl
Research outputs 2022 to 2026
Objective: This paper describes a pilot study, in a small sample of older adults, designed to ascertain the feasibility, acceptability and potential effectiveness of group Cognitive Behavioural Therapy For Insomnia (CBT-I). Methods: Eleven older adults participated in a 3-week group CBT-I intervention with pre- and post-intervention outcome measures of sleep and fatigue. Acceptability was measured via post-intervention focus groups. Feasibility was measured via recruitment, retention and completion data. Subjective sleep outcomes were measured pre- and post-intervention using the Pittsburgh Sleep Quality Index. Fatigue was measured using the Fatigue Severity Index. Objective sleep outcome measures were obtained via pre- and post-intervention …
Perceptions Of Capacity, Fatigue, And Their Psychophysics: Examining Construct Equivalence And The Relationship Between Actual Capacity And Perception Of Capacity During Resisted Elbow Flexion Tasks, James Steele, Matheus D. Pinto, Kazunori Nosaka, James L. Nuzzo
Perceptions Of Capacity, Fatigue, And Their Psychophysics: Examining Construct Equivalence And The Relationship Between Actual Capacity And Perception Of Capacity During Resisted Elbow Flexion Tasks, James Steele, Matheus D. Pinto, Kazunori Nosaka, James L. Nuzzo
Research outputs 2022 to 2026
The actual capacity to perform tasks, and actual fatigue, are concepts that have been thought of as inherently linked. These considerations also extend to their phenomenology, meaning the perception(s) of capacity or fatigue. The phenomenology of capacity or fatigue thus may be capturing the same underlying latent construct. Further, it is speculated that the actual capacity of a person to perform a given task, and their perception of that capacity, have a psychophysical relationship. The aim of this study was therefore twofold: 1) to explore the extensional equivalence of perceptions of capacity and fatigue, and 2) to explore the relationship …
Does Fatigue Influence Joint-Specific Work And Ground Force Production During The First Steps Of Maximal Acceleration?, Shayne Vial, Jodie C. Wilkie, Mitchell Turner, Mark Scanlan, Anthony J. Blazevich
Does Fatigue Influence Joint-Specific Work And Ground Force Production During The First Steps Of Maximal Acceleration?, Shayne Vial, Jodie C. Wilkie, Mitchell Turner, Mark Scanlan, Anthony J. Blazevich
Research outputs 2022 to 2026
During initial acceleration, the first steps of a maximal-effort (sprint) run often determine success or failure in the capture and evasion of an opponent, and is therefore a vital factor of success in many modern sports. However, accelerative events are commonly performed after having already run considerable distances, and the associated fatigue should impair muscle force production and thus reduce acceleration. Despite this, the effects of running-induced fatigue on our ability to accelerate as well as the running technique used to achieve it have received little attention. We recorded 3-D kinematics and ground reaction forces during the first three steps …
Fatigue Risk Management Systems Diagnostic Tool: Validation Of An Organizational Assessment Tool For Shift Work Organizations, Gemma Maisey, Marcus Cattani, Amanda Devine, Ian C. Dunican
Fatigue Risk Management Systems Diagnostic Tool: Validation Of An Organizational Assessment Tool For Shift Work Organizations, Gemma Maisey, Marcus Cattani, Amanda Devine, Ian C. Dunican
Research outputs 2022 to 2026
Background: This study aimed to determine and define the elements of an Fatigue Risk Management System (FRMS) diagnostic tool to assist an organization in systematically assessing its level of implementation of an FRMS. Methods: A modified Delphi process was used involving 16 participants with expertise in sleep science, chronobiology, and fatigue risk management within occupational settings. The study was undertaken in two stages 1) review of elements and definitions; 2) review of statements for each element. Each stage involved an iterative process, and a consensus rule of ≥ 60 % was applied to arrive at a final list of elements, …
Study Protocol: Investigating The Feasibility Of A Hybrid Delivery Of Home-Based Cluster Set Resistance Training For Individuals Previously Treated For Lung Cancer, C. M. Fairman, O. L. Owens, Kristina L. Kendall, J. Steele, Christopher Latella, M. T. Jones, L. Marcotte, Carolyn M. J. Peddle-Mcintyre, K. K. Mcdonnell
Study Protocol: Investigating The Feasibility Of A Hybrid Delivery Of Home-Based Cluster Set Resistance Training For Individuals Previously Treated For Lung Cancer, C. M. Fairman, O. L. Owens, Kristina L. Kendall, J. Steele, Christopher Latella, M. T. Jones, L. Marcotte, Carolyn M. J. Peddle-Mcintyre, K. K. Mcdonnell
Research outputs 2022 to 2026
Background: Symptom burden remains a critical concern for individuals with non-small cell lung cancer (NSCLC) following the completion of treatment. The most common symptom clusters, dyspnea (shortness of breath) and fatigue, can contribute to physical decline, reductions in quality of life, and a higher risk of comorbidities and mortality. Dyspnea is a primary limiter of exercise capacity in individuals with lung cancer, resulting in exercise avoidance and an accelerated physical decline. As such, designing resistance training with cluster sets to mitigate symptoms of dyspnea and fatigue may result in improved exercise tolerance. Thus, maintaining the exercise stimulus via cluster sets, …
Voluntary Activation Of Muscle In Humans: Does Serotonergic Neuromodulation Matter?, Justin J. Kavanagh, Janet L. Taylor
Voluntary Activation Of Muscle In Humans: Does Serotonergic Neuromodulation Matter?, Justin J. Kavanagh, Janet L. Taylor
Research outputs 2022 to 2026
Ionotropic inputs to motoneurones have the capacity to depolarise and hyperpolarise the motoneurone, whereas neuromodulatory inputs control the state of excitability of the motoneurone. Intracellular recordings of motoneurones from in vitro and in situ animal preparations have provided extraordinary insight into the mechanisms that underpin how neuromodulators regulate neuronal excitability. However, far fewer studies have attempted to translate the findings from cellular and molecular studies into a human model. In this review, we focus on the role that serotonin (5-HT) plays in muscle activation in humans. 5-HT is a potent regulator of neuronal firing rates, which can influence the force …