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Full-Text Articles in Medicine and Health Sciences
Mechanical Suppression Of Osteolytic Bone Metastases In Advanced Breast Cancer Patients: A Randomised Controlled Study Protocol Evaluating Safety, Feasibility And Preliminary Efficacy Of Exercise As A Targeted Medicine, Nicolas H. Hart, Daniel A. Galvão, Christobel Saunders, Dennis R. Taaffe, Kynan T. Feeney, Nigel A. Spry, Daphne Tsoi, Hilary Martin, Raphael Chee, Tim Clay, Andrew D. Redfern, Robert U. Newton
Mechanical Suppression Of Osteolytic Bone Metastases In Advanced Breast Cancer Patients: A Randomised Controlled Study Protocol Evaluating Safety, Feasibility And Preliminary Efficacy Of Exercise As A Targeted Medicine, Nicolas H. Hart, Daniel A. Galvão, Christobel Saunders, Dennis R. Taaffe, Kynan T. Feeney, Nigel A. Spry, Daphne Tsoi, Hilary Martin, Raphael Chee, Tim Clay, Andrew D. Redfern, Robert U. Newton
Research outputs 2014 to 2021
BACKGROUND: Skeletal metastases present a major challenge for clinicians, representing an advanced and typically incurable stage of cancer. Bone is also the most common location for metastatic breast carcinoma, with skeletal lesions identified in over 80% of patients with advanced breast cancer. Preclinical models have demonstrated the ability of mechanical stimulation to suppress tumour formation and promote skeletal preservation at bone sites with osteolytic lesions, generating modulatory interference of tumour-driven bone remodelling. Preclinical studies have also demonstrated anti-cancer effects through exercise by minimising tumour hypoxia, normalising tumour vasculature and increasing tumoural blood perfusion. This study proposes to explore the promising …
Relationship Between Strength And Power Production Capacities In Trained Sprint Track Cyclists, James Vercoe, Mike R. Mcguigan
Relationship Between Strength And Power Production Capacities In Trained Sprint Track Cyclists, James Vercoe, Mike R. Mcguigan
Research outputs 2014 to 2021
The purpose of this study was to investigate the relationship between strength and power capabilities in trained sprint track cyclists. Ten participants including six women and four men (age: 22.1±6.8 years, body height: 176.1±6.7 cm, body weight: 72.1±7.9 kg) performed isometric mid-thigh pull (IMTP) and isokinetic sprint tests. Variables measured included peak force (PF), peak rate of force development (PRFD) for the IMTP and maximal torque and maximal power (Pmax) for the isokinetic sprint test. There was a strong relationship between PF on the IMTP and maximal peak torque values across five isokinetic sprints (r=.890-.925). Strong relationships were also shown …