Medicine and Health Sciences Commons^™

Feasibility And Preliminary Efficacy Of A 10-Week Resistance And Aerobic Exercise Intervention During Neoadjuvant Chemoradiation Treatment In Rectal Cancer Patients, Favil Singh, Daniel A. Galvão, Robert Newton, Nigel A. Spry, Michael K. Baker, Dennis Taaffe

Research outputs 2014 to 2021

Background:

Neoadjuvant chemoradiation treatment (CRT) in rectal cancer patients is associated with a reduction in physical capacity, lean mass and increased fatigue. As a countermeasure to these treatment-related adverse effects, we examined the feasibility and preliminary efficacy of a 10-week exercise program during CRT.

Methods:

Ten rectal cancer patients (7 men, aged 27-70 years, body mass index = 26.4 ± 3.8 kg/m2) receiving CRT undertook supervised resistance and aerobic exercise twice weekly. Assessments were undertaken pre- and post-intervention for upper and lower body muscle strength by 1-RM, muscle endurance, physical performance tests, body composition by dual X-ray absorptiometry, quality of …

Geographical Variations In The Clinical Management Of Colorectal Cancer In Australia: A Systematic Review, Fiona Crawford-Williams, Sonja March, Michael Ireland, Arlen Rowe, Belinda Goodwin, Melissa Hyde, Suzanne K. Chambers, Joanne Aitken, Jeff Dunn

Research outputs 2014 to 2021

Background: In Australia, cancer survival is significantly lower in non-metropolitan compared to metropolitan areas. Our objective was to evaluate the evidence on geographical variations in the clinical management and treatment of colorectal cancer (CRC).

Methods: A systematic review of published and gray literature was conducted. Five databases (CINAHL, PubMed, Embase, ProQuest, and Informit) were searched for articles published in English from 1990 to 2018. Studies were included if they assessed differences in clinical management according to geographical location; focused on CRC patients; and were conducted in Australia. Included studies were critically appraised using a modified Newcastle–Ottawa Scale. PRISMA systematic review …

Geographic Disparities In Previously Diagnosed Health Conditions In Colorectal Cancer Patients Are Largely Explained By Age And Area Level Disadvantage, Belinda C Goodwin, Sonja March, Michael J Ireland, Fiona Crawford-Williams, Shu-Kay Ng, Peter D Baade, Suzanne K. Chambers, Joanne F Aitken, Jeff Dunn

Research outputs 2014 to 2021

Background: Geographical disparity in colorectal cancer (CRC) survival rates may be partly due to aging populations and disadvantage in more remote locations; factors that also impact the incidence and outcomes of other chronic health conditions. The current study investigates whether geographic disparity exists amongst previously diagnosed health conditions in CRC patients above and beyond age and area-level disadvantage and whether this disparity is linked to geographic disparity in CRC survival.

Methods: Data regarding previously diagnosed health conditions were collected via computer-assisted telephone interviews with a cross-sectional sample of n = 1,966 Australian CRC patients between 2003 and 2004. Ten-year survival …