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Full-Text Articles in Medicine and Health Sciences
The Capacity Of The Fecal Microbiota From Malawian Infants To Ferment Resistant Starch, Yanan Wang, Elissa K. Mortimer, Kondwani G. H. Katundu, Noel Kalanga, Lex E. X. Leong, Geetha L. Gopalsamy, Claus T. Christophersen, Alyson C. Richard, Aravind Shivasami, Guy C. J. Abell, Graeme P. Young, Geraint B. Rogers
The Capacity Of The Fecal Microbiota From Malawian Infants To Ferment Resistant Starch, Yanan Wang, Elissa K. Mortimer, Kondwani G. H. Katundu, Noel Kalanga, Lex E. X. Leong, Geetha L. Gopalsamy, Claus T. Christophersen, Alyson C. Richard, Aravind Shivasami, Guy C. J. Abell, Graeme P. Young, Geraint B. Rogers
Research outputs 2014 to 2021
In Low and Middle-Income Countries (LMIC), weaning is associated with environmentally acquired and inflammation-associated enteric disorders. Dietary intake of high amylose maize starch (HAMS) can promote commensal fermentative bacteria and drive the production of short chain fatty acids (SCFAs). By stabilizing commensal gut microbiology, and stimulating the production of anti-inflammatory metabolites, HAMS supplementation might therefore influence enteric health. However, the extent to which the gut microbiota of LMIC infants are capable of fermenting HAMS is unclear. We assessed the capacity of the fecal microbiota from pre-weaning and weaning Malawian infants to ferment HAMS and produce SCFAs using an in vitro …