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Full-Text Articles in Medicine and Health Sciences

Implementation Of Continuous Quality Improvement In Aboriginal And Torres Strait Islander Primary Health Care In Australia: A Scoping Systematic Review, Karen Gardner, Beverly Sibthorpe, Mier Chan, Ginny Sargent, Michelle Dowden, Daniel Mcaullay Jul 2018

Implementation Of Continuous Quality Improvement In Aboriginal And Torres Strait Islander Primary Health Care In Australia: A Scoping Systematic Review, Karen Gardner, Beverly Sibthorpe, Mier Chan, Ginny Sargent, Michelle Dowden, Daniel Mcaullay

Research outputs 2014 to 2021

BACKGROUND: Continuous Quality Improvement (CQI) programs have been taken up widely by Indigenous primary health care (PHC) services in Australia and there has been national policy commitment to support this. However, international evidence shows that implementing CQI is challenging, impacts are variable and little is known about the factors that impede or enhance effectiveness. A scoping review was undertaken to explore uptake and implementation in Indigenous PHC, including barriers and enablers to embedding CQI in routine practice. We provide guidance on how research and evaluation might be intensified to support implementation.

METHODS: Searches were conducted in MEDLINE, CINAHL and the …


Dietary Flavonoids And The Prevalence And 15-Y Incidence Of Age-Related Macular Degeneration, Bamini Gopinath, Gerald Liew, Annette Kifley, Victoria M. Flood, Nichole Joachim, Joshua Lewis, Jonathan M. Hodgson, Paul Mitchell Jul 2018

Dietary Flavonoids And The Prevalence And 15-Y Incidence Of Age-Related Macular Degeneration, Bamini Gopinath, Gerald Liew, Annette Kifley, Victoria M. Flood, Nichole Joachim, Joshua Lewis, Jonathan M. Hodgson, Paul Mitchell

Research outputs 2014 to 2021

Background: The majority of research performed to date has examined the effects of commonly known antioxidants such as vitamins C, E, and A and carotenoids on age-related macular degeneration (AMD) risk and progression. To date, there is limited research on promising phytochemicals with antioxidant and anti-inflammatory properties, including flavonoids.

Objective: In this exploratory study, we aimed to assess the independent associations between dietary intake of total flavonoids and common flavonoid classes with the prevalence and 15-y incidence of AMD.

Design: In this population-based cohort study, 2856 adults aged ≥49 y at baseline and 2037 followed up 15 …


Personality Characteristics Are Independently Associated With Prospective Memory In The Laboratory, And In Daily Life, Among Older Adults, Kerry A. Mccabe, Steven Paul Woods, Michael Weinborn, Hamid R. Sohrabi, Stephanie Rainey-Smith, Belinda M. Brown, Samantha Gardener, Kevin Taddei, Ralph Martins Jun 2018

Personality Characteristics Are Independently Associated With Prospective Memory In The Laboratory, And In Daily Life, Among Older Adults, Kerry A. Mccabe, Steven Paul Woods, Michael Weinborn, Hamid R. Sohrabi, Stephanie Rainey-Smith, Belinda M. Brown, Samantha Gardener, Kevin Taddei, Ralph Martins

Research outputs 2014 to 2021

Prospective memory (PM) can deteriorate with age and adversely influence health behaviours. Research suggests that personality is related to PM in healthy young adults, but we know little about the role of personality in the PM amongst older adults. Community-dwelling older adults (N = 152) completed the NEO Five-Factor Inventory-3 and PM measures. After adjusting for demographics and general cognition, higher neuroticism and lower levels of openness were independently associated with lower objectively-measured time- and event-based PM. Lower conscientiousness was the only personality predictor of self-reported everyday PM failures. Findings indicate that personality plays a role in PM functioning in …


The Assessment Of Isometric, Dynamic, And Sports-Specific Upper-Body Strength In Male And Female Competitive Surfers, Joanna Parsonage, Josh Secomb, Rebecca Dowse, Brendon Ferrier, Jeremy Sheppard, Sophia Nimphius Jun 2018

The Assessment Of Isometric, Dynamic, And Sports-Specific Upper-Body Strength In Male And Female Competitive Surfers, Joanna Parsonage, Josh Secomb, Rebecca Dowse, Brendon Ferrier, Jeremy Sheppard, Sophia Nimphius

Research outputs 2014 to 2021

The primary purpose of this study was to investigate gender differences in the dynamic strength index (DSI): an assessment of upper-body dynamic strength relative to maximal isometric strength. The secondary purpose was to investigate gender differences in the dynamic skill deficit (DSD): an assessment of sports-specific dynamic strength relative to maximal isometric strength, and its association with a sports-specific performance measure in surfers. Nine male (age = 30.3 ± 7.3 yrs) and eight female (age = 25.5 ± 5.2 yrs) surfers undertook three upper-body assessments: isometric push-up, dynamic push-up, and a force plate pop-up to determine the DSI and DSD. …


The Effects Of Alcohol On Plasma Lipid Mediators Of Inflammation Resolution In Patients With Type 2 Diabetes Mellitus, Anne Barden, Sujata Shinde, Michael Phillips, Lawrence Beilin, Emilie Mas, Jonathan M. Hodgson, Ian Puddey, Trevor A. Mori Jun 2018

The Effects Of Alcohol On Plasma Lipid Mediators Of Inflammation Resolution In Patients With Type 2 Diabetes Mellitus, Anne Barden, Sujata Shinde, Michael Phillips, Lawrence Beilin, Emilie Mas, Jonathan M. Hodgson, Ian Puddey, Trevor A. Mori

Research outputs 2014 to 2021

Background

Type 2 diabetes mellitus is characterized by peripheral insulin resistance and low-grade systemic inflammation. Inflammation resolution is recognised as an important process driven by specialised pro-resolving mediators of inflammation (SPMs) and has the potential to moderate chronic inflammation. Alcohol has the potential to affect synthesis of SPMs by altering key enzymes involved in SPM synthesis and may influence ongoing inflammation associated with Type 2 diabetes mellitus.

Aims

(i) To examine the effects of alcohol consumed as red wine on plasma SPM in men and women with Type 2 diabetes in a randomised controlled trial and (ii) compare baseline plasma …


Reply To Om Shannon Et Al, Lauren C. Blekkenhorst, Joshua R. Lewis, Richard L. Prince, Amanda Devine, Nicola P. Bondonno, Catherine P. Bondonno, Lisa G. Wood, Ian B. Puddey, Natalie C. Ward, Kevin D. Croft, Richard J. Woodman, Lawrence J. Beilin, Jonathan M. Hodgson Jun 2018

Reply To Om Shannon Et Al, Lauren C. Blekkenhorst, Joshua R. Lewis, Richard L. Prince, Amanda Devine, Nicola P. Bondonno, Catherine P. Bondonno, Lisa G. Wood, Ian B. Puddey, Natalie C. Ward, Kevin D. Croft, Richard J. Woodman, Lawrence J. Beilin, Jonathan M. Hodgson

Research outputs 2014 to 2021

No abstract provided.


Intense Exercise For Survival Among Men With Metastatic Castrate-Resistant Prostate Cancer (Interval-Gap4): A Multicentre, Randomised, Controlled Phase Iii Study Protocol, Robert Newton, Stacey A Kenfield, Nicolas H. Hart, June M Chan, Kerry S. Courneya, James Catto, Stephen P Finn, Rosemary Greenwood, Daniel C Hughes, Lorelei Mucci, Stephen R Plymate, Stephan F E Praet, Emer M Guinan, Erin L Van Blarigan, Orla Casey, Mark Buzza, Sam Gledhill, Li Zhang, Daniel A. Galvao, Charles J Ryan, Fred Saad May 2018

Intense Exercise For Survival Among Men With Metastatic Castrate-Resistant Prostate Cancer (Interval-Gap4): A Multicentre, Randomised, Controlled Phase Iii Study Protocol, Robert Newton, Stacey A Kenfield, Nicolas H. Hart, June M Chan, Kerry S. Courneya, James Catto, Stephen P Finn, Rosemary Greenwood, Daniel C Hughes, Lorelei Mucci, Stephen R Plymate, Stephan F E Praet, Emer M Guinan, Erin L Van Blarigan, Orla Casey, Mark Buzza, Sam Gledhill, Li Zhang, Daniel A. Galvao, Charles J Ryan, Fred Saad

Research outputs 2014 to 2021

INTRODUCTION: Preliminary evidence supports the beneficial role of physical activity on prostate cancer outcomes. This phase III randomised controlled trial (RCT) is designed to determine if supervised high-intensity aerobic and resistance exercise increases overall survival (OS) in patients with metastatic castrate-resistant prostate cancer (mCRPC).

METHODS AND ANALYSIS: Participants (n=866) must have histologically documented metastatic prostate cancer with evidence of progressive disease on androgen deprivation therapy (defined as mCRPC). Patients can be treatment-naïve for mCRPC or on first-line androgen receptor-targeted therapy for mCRPC (ie, abiraterone or enzalutamide) without evidence of progression at enrolment, and with no prior chemotherapy for mCRPC. Patients …


Test-Retest Reliability Of The Short-Form Survivor Unmet Needs Survey, Karen Taylor, Max Bulsara, Leanne Monterosso Apr 2018

Test-Retest Reliability Of The Short-Form Survivor Unmet Needs Survey, Karen Taylor, Max Bulsara, Leanne Monterosso

Research outputs 2014 to 2021

Objective: Reliable and valid needs assessment measures are important assessment tools in cancer survivorship care. A new 30-item short-form version of the Survivor Unmet Needs Survey (SF-SUNS) was developed and validated with cancer survivors, including hematology cancer survivors; however, test-retest reliability has not been established. The objective of this study was to assess the test-retest reliability of the SF-SUNS with a cohort of lymphoma survivors (n = 40).

Methods: Test-retest reliability of the SF-SUNS was conducted at two time points: baseline (time 1) and 5 days later (time 2). Test-retest data were collected from lymphoma cancer survivors (n …


Living With Multiple Myeloma: A Focus Group Study Of Unmet Needs And Preferences For Survivorship Care, Leanne Monterosso, Karen Taylor, Violet Platt, Elizabeth Lobb, Toni Musiello, Caroline Bulsara, Kendall Stratton, David Joske, Meinir Krishnasamy Mar 2018

Living With Multiple Myeloma: A Focus Group Study Of Unmet Needs And Preferences For Survivorship Care, Leanne Monterosso, Karen Taylor, Violet Platt, Elizabeth Lobb, Toni Musiello, Caroline Bulsara, Kendall Stratton, David Joske, Meinir Krishnasamy

Research outputs 2014 to 2021

Purpose: To describe the unmet informational, psychological, emotional, social, practical, and physical needs and preferences for posttreatment survivorship care of individuals living with multiple myeloma to inform the development of relevant, person-centered, survivorship services. Methods: An exploratory, descriptive study using 2 focus groups with 14 participants, 6 to 49 months postdiagnosis. Results: Thematic analysis revealed 7 key themes: information needs, experience with health-care professionals, coping with side effects, communicating with family and friends, dealing with emotions, support needs, and living with the chronicity of myeloma. Participants described key characteristics of survivorship care relevant to their needs and indicated they would …


Design Of A Framework For The Deployment Of Collaborative Independent Rare Disease-Centric Registries: Gaucher Disease Registry Model, Matthew I. Bellgard, Kathryn R. Napier, Alan Bittles, Jeffrey Szer, Sue Fletcher, Nikolajs Zeps, Adam A. Hunter, Jack Goldblatt Feb 2018

Design Of A Framework For The Deployment Of Collaborative Independent Rare Disease-Centric Registries: Gaucher Disease Registry Model, Matthew I. Bellgard, Kathryn R. Napier, Alan Bittles, Jeffrey Szer, Sue Fletcher, Nikolajs Zeps, Adam A. Hunter, Jack Goldblatt

Research outputs 2014 to 2021

Orphan drug clinical trials often are adversely affected by a lack of high quality treatment efficacy data that can be reliably compared across large patient cohorts derived from multiple governmental and country jurisdictions. It is critical that these patient data be captured with limited corporate involvement. For some time, there have been calls to develop collaborative, non-proprietary, patient-centric registries for post-market surveillance of aspects related to orphan drug efficacy. There is an urgent need for the development and sustainable deployment of these ‘independent’ registries that can capture comprehensive clinical, genetic and therapeutic information on patients with rare diseases. We therefore …


What Are The Characteristics Of Vitamin D Metabolism In Opioid Dependence? An Exploratory Longitudinal Study In Australian Primary Care, Albert Stuart Reece, Gary Hulse Jan 2018

What Are The Characteristics Of Vitamin D Metabolism In Opioid Dependence? An Exploratory Longitudinal Study In Australian Primary Care, Albert Stuart Reece, Gary Hulse

Research outputs 2014 to 2021

OBJECTIVE: Compare vitamin D levels in opioid dependence and control population and adjust for relevant confounding effects. Nuclear hormone receptors (including the vitamin D receptor) have been shown to be key transducers and regulators of intracellular metabolism and comprise an important site of pathophysiological immune and metabolic dysregulation potentially contributing towards pro-ageing changes observed in opioid-dependent patients (ODPs).

DESIGN: Longitudinal prospective comparing ODPs with general medical controls (GMCs).

SETTING: Primary care.

PARTICIPANTS: Prospective review comparing 1168 ODP (72.5% men) and 415 GMC (51.6% men, p

INTERVENTIONS: Nil. Observational study only.

PRIMARY AND SECONDARY OUTCOMES: Serum vitamin D levels and relevant …


Feasibility And Preliminary Efficacy Of A 10-Week Resistance And Aerobic Exercise Intervention During Neoadjuvant Chemoradiation Treatment In Rectal Cancer Patients, Favil Singh, Daniel A. Galvão, Robert Newton, Nigel A. Spry, Michael K. Baker, Dennis Taaffe Jan 2018

Feasibility And Preliminary Efficacy Of A 10-Week Resistance And Aerobic Exercise Intervention During Neoadjuvant Chemoradiation Treatment In Rectal Cancer Patients, Favil Singh, Daniel A. Galvão, Robert Newton, Nigel A. Spry, Michael K. Baker, Dennis Taaffe

Research outputs 2014 to 2021

Background:

Neoadjuvant chemoradiation treatment (CRT) in rectal cancer patients is associated with a reduction in physical capacity, lean mass and increased fatigue. As a countermeasure to these treatment-related adverse effects, we examined the feasibility and preliminary efficacy of a 10-week exercise program during CRT.

Methods:

Ten rectal cancer patients (7 men, aged 27-70 years, body mass index = 26.4 ± 3.8 kg/m2) receiving CRT undertook supervised resistance and aerobic exercise twice weekly. Assessments were undertaken pre- and post-intervention for upper and lower body muscle strength by 1-RM, muscle endurance, physical performance tests, body composition by dual X-ray absorptiometry, quality of …


“…Like You’Re Pushing The Snowball Back Up Hill”—The Experiences Of Australian Physiotherapists Promoting Non-Treatment Physical Activity: A Qualitative Study, Breanne E. Kunstler, Paul D. O'Halloran, Jill L. Cook, Joanne L. Kemp, Caroline Finch Jan 2018

“…Like You’Re Pushing The Snowball Back Up Hill”—The Experiences Of Australian Physiotherapists Promoting Non-Treatment Physical Activity: A Qualitative Study, Breanne E. Kunstler, Paul D. O'Halloran, Jill L. Cook, Joanne L. Kemp, Caroline Finch

Research outputs 2014 to 2021

Participating in physical activity is important for maintaining general health. When physiotherapists promote physical activity for the purposes of maintaining or improving a patient‟s general health, they are promoting non-treatment physical activity. Physiotherapists have a responsibility to promote non-treatment physical activity to their patients while also providing the patient with treatment for their presenting complaint. This qualitative study explored the experiences of Australian physiotherapists promoting non-treatment physical activity to patients with musculoskeletal conditions. Ten Australian physiotherapists treating patients with musculoskeletal conditions in private practice and outpatient settings were recruited using a social media campaign and snowballing. All interviewees received one …


Prescribing Target Running Intensities For High-School Athletes: Can Forward And Backward Running Performance Be Autoregulated?, Aaron Uthoff, Jon Oliver, John Cronin, Paul Winwood, Craig Harrison Jan 2018

Prescribing Target Running Intensities For High-School Athletes: Can Forward And Backward Running Performance Be Autoregulated?, Aaron Uthoff, Jon Oliver, John Cronin, Paul Winwood, Craig Harrison

Research outputs 2014 to 2021

Target running intensities are prescribed to enhance sprint-running performance and progress injured athletes back into competition, yet is unknown whether running speed can be achieved using autoregulation. This study investigated the consistency of running intensities in adolescent athletes using autoregulation to self-select velocity. Thirty-four boys performed 20 m forward running (FR) and backward running (BR) trials at slow, moderate and fast intensities (40–55%, 60–75% and +90% maximum effort, respectively) on three occasions. Absolute and relative consistency was assessed using the coefficient of variation (CV) and intraclass correlation coefficients (ICC). Systematic changes in 10 and 20 m performance were identified between …


Effect Of Plyometric Training On Speed And Change Of Direction Ability In Elite Field Hockey Players, Jasdev Singh, Brendyn B. Appleby, Andrew P. Lavender Jan 2018

Effect Of Plyometric Training On Speed And Change Of Direction Ability In Elite Field Hockey Players, Jasdev Singh, Brendyn B. Appleby, Andrew P. Lavender

Research outputs 2014 to 2021

This study investigated the effects of two plyometric training protocols on sprint and change of direction (COD) performance in elite hockey players. A parallel-group randomized controlled trial design was used and seventeen elite male and female field hockey players were randomly allocated into either low-to-high (L-H, n = 8) or high-to-low (H-L, n = 9) training groups. Each group performed separate variations of the drop jump exercise twice weekly for six weeks, with an emphasis on either jump height (L-H) or drop height (H-L). Performance variables assessed included sprint times over 10 m and 20 m, as well as 505 …


Uv Light-Blocking Contact Lenses Protect Against Short-Term Uvb-Induced Limbal Stem Cell Niche Damage And Inflammation, M. Notara, S. Behboudifard, M. A. Kluth, C. Maßlo, C. Ganss, M. H. Frank, B. Schumacher, C. Cursiefen Jan 2018

Uv Light-Blocking Contact Lenses Protect Against Short-Term Uvb-Induced Limbal Stem Cell Niche Damage And Inflammation, M. Notara, S. Behboudifard, M. A. Kluth, C. Maßlo, C. Ganss, M. H. Frank, B. Schumacher, C. Cursiefen

Research outputs 2014 to 2021

UVB irradiation has been linked to pathogenesis of pterygium, a conjunctival tumor growing onto transparent cornea, the windscreen of the eye. Due to corneal anatomy, ambient UVB irradiation is amplified at the stem cell-containing nasal limbus. The aim of this study was to analyse the effect of a UV-blocking contact lens (UVBCL, senofilcon A, Class 1 UV blocker) on limbal epithelial cells and fibroblasts under UVB irradiation compared to a non-UVB-blocking contact lens. UVBCL prevented UVB-induced DNA damage (as assessed by cyclobutane pyrimidine dimer immunostaining) as well as a decrease in proliferation and scratch wound closure rate of both limbal …


Seed Coats Of Pulses As A Food Ingredient: Characterization, Processing, And Applications, Liezhou Zhong, Zhongxiang Fang, Mark L. Wahlqvist, Gangcheng Wu, Jonathan M. Hodgson, Stuart K. Johnson Jan 2018

Seed Coats Of Pulses As A Food Ingredient: Characterization, Processing, And Applications, Liezhou Zhong, Zhongxiang Fang, Mark L. Wahlqvist, Gangcheng Wu, Jonathan M. Hodgson, Stuart K. Johnson

Research outputs 2014 to 2021

Background In recognition of their multiple benefits on environment, food security, and human health, pulses are attracting worldwide attention. The seed coat is a major by-product of pulse processing, and its only markets are as low value ruminant feed and very limited use in high fibre foods. Recently, accumulating studies have suggested that this underutilised by-product has greater potential as a novel natural “nutritious dietary fibre” which can be used as a functional food ingredient.

Scope and approach This review discusses biochemical and physicochemical functionalities of seed coats of six globally important pulses: chickpea, field pea, faba/broad bean, lentil and …


Whole Body Vibration Exposure On Markers Of Bone Turnover, Body Composition, And Physical Functioning In Breast Cancer Patients Receiving Aromatase Inhibitor Therapy: A Randomized Controlled Trial, Michael K. Baker, Carolyn J. Mcintyre, Daniel A. Galvão, Catherine Hunt, Nigel Spry, Robert Newton Jan 2018

Whole Body Vibration Exposure On Markers Of Bone Turnover, Body Composition, And Physical Functioning In Breast Cancer Patients Receiving Aromatase Inhibitor Therapy: A Randomized Controlled Trial, Michael K. Baker, Carolyn J. Mcintyre, Daniel A. Galvão, Catherine Hunt, Nigel Spry, Robert Newton

Research outputs 2014 to 2021

Introduction: Women with breast cancer are often prescribed aromatase inhibitors, which can cause rapid loss of bone mass leading to significant potential for morbidity. Vibration training has been shown to be helpful in reducing bone turnover in postmenopausal women without cancer.

Aim: To examine the effect of vibration stimulus on markers of bone turnover in breast cancer patients receiving aromatase inhibitors.

Methods: Thirty-one breast cancer survivors undergoing treatment with aromatase inhibitors were randomized to vibration stimulus (n = 14) or usual care control (n = 17). Low-frequency and low-magnitude vibration stimulus (27-32 Hz, 0.3g) was delivered in supervised …


A Comparison Of Displacement And Energetic Variables Between Three Team Sport Gps Devices, Paolo Terziotti, Marc Sim, Ted Polglaze Jan 2018

A Comparison Of Displacement And Energetic Variables Between Three Team Sport Gps Devices, Paolo Terziotti, Marc Sim, Ted Polglaze

Research outputs 2014 to 2021

This study compared the outputs of three different commercially-available GPS player-tracking devices for a range of commonly used displacement and energetic variables in activities replicating team sport movements. Professional male soccer players (n = 7), simultaneously wore three GPS devices (Catapult OptimEye S5, GPExe Pro 1, StatSport ViperPod) whilst completing four separate drills, comprising progressively more complex changes in speed and direction. Displacement (distance, speed) and energetic (energy cost, metabolic power, energy expenditure) variables were compared for each device. All three devices tended to under-estimate distance compared to the known value for each drill, with only minor and inconsistent …


Attitudes Of Doctors And Nurses Toward Patient Safety Within Emergency Departments Of Two Saudi Arabian Hospitals, Naif Alzahrani, Russell Jones, Mohamed E. Abdel-Latif Jan 2018

Attitudes Of Doctors And Nurses Toward Patient Safety Within Emergency Departments Of Two Saudi Arabian Hospitals, Naif Alzahrani, Russell Jones, Mohamed E. Abdel-Latif

Research outputs 2014 to 2021

Background: A hospital culture that promotes and insures patient safety is a critical aspect for the effective delivery of hospital services and patient care. Yet there are significant patient health and safety issues in hospitals worldwide. This study aims to investigate doctors’ and nurses’ attitudes toward patient safety in the emergency departments (ED) of two Saudi hospitals.

Method: A cross-sectional survey using a validated Safety Attitudes Questionnaire (SAQ) was used. Total of 503 ED doctors and nurses completed SAQ. Correlation analysis, using Spearman’s Rho, was performed between the number of incidents reported and each dimension of the SAQ. …


Bridging The Gap Between Clinicians And Fitness Professionals, Rachele Pojednic, Amy Bantham, Fred Arnstein, Mary A. Kennedy, Edward Phillips Jan 2018

Bridging The Gap Between Clinicians And Fitness Professionals, Rachele Pojednic, Amy Bantham, Fred Arnstein, Mary A. Kennedy, Edward Phillips

Research outputs 2014 to 2021

Objective Health clubs (HC) and personal trainers (PT) are traditional outlets for the promotion of physical activity (PA) and exercise programming. As physicians are increasingly being called on to write exercise prescriptions for their patients, this study sought to investigate the level of integration between the healthcare and fitness systems.

Design An internet study was designed with five domains to understand physicians’: (1) overall perception of HC, (2) appropriateness and recommendation of HC and PT to their patients, (3) attitude regarding specific aspects of HC, (4) support of patient participation in HC sponsored exercise and (5) elements of HC that …


The Weakening Of Kin Ties: Exploring The Need For Life-World Led Interventions, Gert Schout, Gideon De Jong Jan 2018

The Weakening Of Kin Ties: Exploring The Need For Life-World Led Interventions, Gert Schout, Gideon De Jong

Research outputs 2014 to 2021

The protective features that families and wider social relationships can have are required to meet the demands of life in contemporary Western societies. Choice and detraditionalization, however; impede this source of solidarity. Family Group Conferencing (FGC) and other life-world led interventions have the potential to strengthen primary groups. This paper explores the need for such a social intervention, using insights from sociological and philosophical theories and empirical findings from a case study of the research project ‘FGC in mental health’. This need is understandable considering the weakening of kin ties, the poor qualities of state agencies to mobilise self-care and …


Flavonoid-Rich Apple Improves Endothelial Function In Individuals At Risk For Cardiovascular Disease: A Randomized Controlled Clinical Trial, Nicola P. Bondonno, Catherine P. Bondonno, Lauren C. Blekkenhorst, Michael J. Considine, Ghassan Maghzal, Roland Stocker, Richard J. Woodman, Natalie C. Ward, Jonathan M. Hodgson, Kevin D. Croft Jan 2018

Flavonoid-Rich Apple Improves Endothelial Function In Individuals At Risk For Cardiovascular Disease: A Randomized Controlled Clinical Trial, Nicola P. Bondonno, Catherine P. Bondonno, Lauren C. Blekkenhorst, Michael J. Considine, Ghassan Maghzal, Roland Stocker, Richard J. Woodman, Natalie C. Ward, Jonathan M. Hodgson, Kevin D. Croft

Research outputs 2014 to 2021

Scope

The cardioprotective effects of apples are primarily attributed to flavonoids, found predominantly in the skin. This study aimed to determine if acute and/or chronic (4 weeks) ingestion of flavonoid-rich apples improves endothelial function, blood pressure (BP), and arterial stiffness in individuals at risk for cardiovascular diseases (CVD).

Methods and results

In this randomized, controlled cross-over trial, acute and 4 week intake of apple with skin (high flavonoid apple, HFA) is compared to intake of apple flesh only (low flavonoid apple, LFA) in 30 participants. The primary outcome is endothelial function assessed using flow-mediated dilation (FMD) of the brachial artery, …


Women’S Experiences Of Vulvodynia: An Interpretative Phenomenological Analysis Of The Journey Toward Diagnosis, Rebekah Shallcross, Joanne M. Dickson, David Nunns, Kate Taylor, Gundi Kiemle Jan 2018

Women’S Experiences Of Vulvodynia: An Interpretative Phenomenological Analysis Of The Journey Toward Diagnosis, Rebekah Shallcross, Joanne M. Dickson, David Nunns, Kate Taylor, Gundi Kiemle

Research outputs 2014 to 2021

Vulvodynia is the experience of idiopathic pain characterized by burning, soreness, or throbbing in the external female genitalia or vulva and is estimated to be experienced by 4–16% of the female population, yet only half of women seek help regarding their symptoms. Of the women who do seek help, only around 2% obtain a diagnosis. Therefore, the aim of the current study was to explore the experiences of women with vulvodynia on their journey toward diagnosis, by using semi-structured interviews and an interpretative phenomenological analysis (IPA) methodology. Eight women were interviewed, and their experiences were analyzed and interpreted into three …


Low-Level Cadmium Exposure And Cardiovascular Outcomes In Elderly Australian Women: A Cohort Study, Kane Deering, Anna C. Callan, Richard Prince, Wai Lim, Peter Thompson, Joshua Lewis, Andrea Hinwood, Amanda Devine Jan 2018

Low-Level Cadmium Exposure And Cardiovascular Outcomes In Elderly Australian Women: A Cohort Study, Kane Deering, Anna C. Callan, Richard Prince, Wai Lim, Peter Thompson, Joshua Lewis, Andrea Hinwood, Amanda Devine

Research outputs 2014 to 2021

Background

Cadmium has been associated with increased risk of cardiovascular disease (CVD) in observational studies, however there has been a limited focus on this relationship in women.

Objectives

This study investigated the association of urinary cadmium (UCd) concentrations with CVD outcomes and all-cause mortality in elderly Western Australian (WA) women.

Methods

UCd excretion was measured at baseline in 1359 women, mean age 75.2 ± 2.7 years and 14.5 years of atherosclerotic vascular disease (ASVD) hospitalisations and deaths, including both the principle cause of death and all associated causes of death. Health outcome data were retrieved from the Western Australian Data …


Genetic Variation In Aquaporin-4 Moderates The Relationship Between Sleep And Brain Aβ-Amyloid Burden, Stephanie Rainey-Smith, Gavin N. Mazzucchelli, Victor L. Villemagne, Belinda M. Brown, Tenielle Porter, Michael Weinborn, Romola Bucks, Lidija Milicic, Hamid R. Sohrabi, Kevin Taddei, David J. Ames, Paul T. Maruff, Colin L. Masters, Christopher C. Rowe, Olivier Salvado, Ralph N. Martins, Simon M. Laws Jan 2018

Genetic Variation In Aquaporin-4 Moderates The Relationship Between Sleep And Brain Aβ-Amyloid Burden, Stephanie Rainey-Smith, Gavin N. Mazzucchelli, Victor L. Villemagne, Belinda M. Brown, Tenielle Porter, Michael Weinborn, Romola Bucks, Lidija Milicic, Hamid R. Sohrabi, Kevin Taddei, David J. Ames, Paul T. Maruff, Colin L. Masters, Christopher C. Rowe, Olivier Salvado, Ralph N. Martins, Simon M. Laws

Research outputs 2014 to 2021

The glymphatic system is postulated to be a mechanism of brain Aβ-Amyloid clearance and to be most effective during sleep. Ablation of the astrocytic end-feet expressed water-channel protein, Aquaporin-4, in mice, results in impairment of this clearance mechanism and increased brain Aβ-Amyloid deposition, suggesting that Aquaporin-4 plays a pivotal role in glymphatic function. Currently there is a paucity of literature regarding the impact of AQP4 genetic variation on sleep, brain Aβ-Amyloid burden and their relationship to each other in humans. To address this a cross-sectional observational study was undertaken in cognitively normal older adults from the Australian Imaging, Biomarkers and …


In The Shadow Of The Ivory Tower: Experiences Of Midwives And Nurses Undertaking Phds, Sadie Geraghty, Kim Oliver Jan 2018

In The Shadow Of The Ivory Tower: Experiences Of Midwives And Nurses Undertaking Phds, Sadie Geraghty, Kim Oliver

Research outputs 2014 to 2021

Aims: The aims of this study were to gain an understanding of the experiences of nurses and midwives enrolled in a PhD, explore any barriers that PhD students encounter whilst completing the degree, and develop recommendations for consideration in formulating support strategies to encourage completion for nurses and midwives enrolled on a PhD degree. Background: It is important to understand what is happening at doctoral level education for nurses and midwives, and how those enrolled on PhD courses can successfully complete their studies, transition learning, and acquire the ability to undertake research into the clinical environments. Design: The criteria for …


Rpe Vs. Percentage 1rm Loading In Periodized Programs Matched For Sets And Repetitions, Eric R. Helms, Ryan K. Byrnes, Daniel M. Cooke, Michael H. Haischer, Joseph P. Carzoli, Trevor K. Johnson, Matt R. Cross, John B. Cronin, Adam G. Storey, Michael C. Zourdos Jan 2018

Rpe Vs. Percentage 1rm Loading In Periodized Programs Matched For Sets And Repetitions, Eric R. Helms, Ryan K. Byrnes, Daniel M. Cooke, Michael H. Haischer, Joseph P. Carzoli, Trevor K. Johnson, Matt R. Cross, John B. Cronin, Adam G. Storey, Michael C. Zourdos

Research outputs 2014 to 2021

Purpose: To investigate differences between rating of perceived exertion (RPE) and percentage one-repetition maximum (1RM) load assignment in resistance-trained males (19-35 years) performing protocols with matched sets and repetitions differentiated by load-assignment. Methods: Participants performed squats then bench press 3x/weeks in a daily undulating format over 8-weeks. Participants were counterbalanced by pre-test 1RM then assigned to percentage 1RM (1RMG, n = 11); load-assignment via percentage 1RMs, or RPE groups (RPEG, n = 10); participant-selected loads to reach target RPE ranges. Ultrasonography determined pre and post-test pectoralis (PMT), and vastus lateralis muscle thickness at 50 (VLMT50) and 70% (VLMT70) femur-length. Results: …


The Nexus Of Nursing Leadership And A Culture Of Safer Patient Care, Melanie Murray, Deborah R. Sundin, Vicki C. Cope Jan 2018

The Nexus Of Nursing Leadership And A Culture Of Safer Patient Care, Melanie Murray, Deborah R. Sundin, Vicki C. Cope

Research outputs 2014 to 2021

Aims and objectives: To explore the connection between +6 nursing leadership and enhanced patient safety. Background: Critical reports from the Institute of Medicine in 1999 and Francis QC report of 2013 indicate that healthcare organisations, inclusive of nursing leadership, were remiss or inconsistent in fostering a culture of safety. The factors required to foster organisational safety culture include supportive leadership, effective communication, an orientation programme and ongoing training, appropriate staffing, open communication regarding errors, compliance to policy and procedure, and environmental safety and security. As nurses have the highest patient interaction, and leadership is discernible at all levels of nursing, …


Factors Associated With The Use Of Complementary And Alternative Medicines For Prostate Cancer By Long-Term Survivors, Sam Egger, Suzanne Hughes, David P. Smith, Suzanne Chambers, Clare Kahn, Annette Moxey, Dianne L. O'Connell Jan 2018

Factors Associated With The Use Of Complementary And Alternative Medicines For Prostate Cancer By Long-Term Survivors, Sam Egger, Suzanne Hughes, David P. Smith, Suzanne Chambers, Clare Kahn, Annette Moxey, Dianne L. O'Connell

Research outputs 2014 to 2021

Objective

To assess whether the use of complementary and alternative medicines therapies (CAMs) for prostate cancer and/or its treatment side effects by long-term survivors is associated with selected socio-demographic, clinical, health-related quality-of-life (HRQOL) and/or psychological factors.

Design, setting and participants

The Prostate Cancer Care and Outcomes Study (PCOS) is a population-based cohort study of men with prostate cancer who were aged less than 70 years at diagnosis in New South Wales, Australia. Included in these analyses were men who returned a 10-year follow-up questionnaire, which included questions about CAM use.

Methods

Validated instruments assessed patient’s HRQOL and psychological well-being. Poisson …