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Articles 31 - 60 of 79
Full-Text Articles in Medicine and Health Sciences
Positive Patient Experiences In An Australian Integrative Oncology Centre, Bonnie J. Furzer, Anna S. Petterson, Kemi E. Wright, Karen E. Wallman, Timothy R. Ackland, David J. Joske
Positive Patient Experiences In An Australian Integrative Oncology Centre, Bonnie J. Furzer, Anna S. Petterson, Kemi E. Wright, Karen E. Wallman, Timothy R. Ackland, David J. Joske
Research outputs 2014 to 2021
Background: The purpose of this study was to explore the experiences of cancer patients' utilising complementary and integrative therapies (CIT) within integrative oncology centres across Western Australia.Methods: Across four locations 135 patients accessed CIT services whilst undergoing outpatient medical treatment for cancer. Of the 135 patients, 66 (61 ± 12 y; female n = 45; male n = 21) agreed to complete a personal accounts questionnaire consisting of open-ended questions designed to explore patients' perceptions of CIT. All results were transcribed into nVivo (v9) and using thematic analysis, key themes were identified.Results: Of the 66 participants, 100% indicated they would …
Psychophysiological Research Of Borderline Personality Disorder: Review And Implications For Biosocial Theory, Tara Cavazzi, Rodrigo Becerra
Psychophysiological Research Of Borderline Personality Disorder: Review And Implications For Biosocial Theory, Tara Cavazzi, Rodrigo Becerra
Research outputs 2014 to 2021
According to the Biosocial theory, Borderline Personality Disorder (BPD) is developed by a biological predisposition to hyperarousal and hyperreactivity combined with an invalidating environment. Although widely supported by subjective measures, the impaired insight present in BPD may skew results, and thus psychophysiological measures have been suggested as an alternative method of examining possible biological differences in BPD. The current review aimed to critically assess psychophysiological research of BPD by electronic searching of relevant databases, with 22 articles meeting inclusion criteria. Results showed that in contrast to the hyperarousal proposed in the Biosocial theory, BPD was associated with hypoarousal and hyporeactivity …
Messages That Increase Women's Intentions To Abstain From Alcohol During Pregnancy: Results From Quantitative Testing Of Advertising Concepts, Kathryn E. France, Robert J. Donovan, Carol Bower, Elizabeth J. Elliott, Janet M. Payne, Heather D'Antoine, Anne E. Bartu
Messages That Increase Women's Intentions To Abstain From Alcohol During Pregnancy: Results From Quantitative Testing Of Advertising Concepts, Kathryn E. France, Robert J. Donovan, Carol Bower, Elizabeth J. Elliott, Janet M. Payne, Heather D'Antoine, Anne E. Bartu
Research outputs 2014 to 2021
Background: Public awareness-raising campaigns targeting alcohol use during pregnancy are an important part of preventing prenatal alcohol exposure and Fetal Alcohol Spectrum Disorder. Despite this, there is little evidence on what specific elements contribute to campaign message effectiveness. This research evaluated three different advertising concepts addressing alcohol and pregnancy: a threat appeal, a positive appeal promoting a self-efficacy message, and a concept that combined the two appeals. The primary aim was to determine the effectiveness of these concepts in increasing women's intentions to abstain from alcohol during pregnancy. Methods. Women of childbearing age and pregnant women residing in Perth, Western …
Risk Factors Of Cvd Mortality Among The Elderly In Beijing, 1992 - 2009: An 18-Year Cohort Study, Tao Zhou, Xia Li, Zhe Tang, Changchun Xie, Lixin Tao, Lei Pan, Da Huo, Fei Sun, Yanxia Luo, Wei Wang, Aoshuang Yan, Xiuhua Guo
Risk Factors Of Cvd Mortality Among The Elderly In Beijing, 1992 - 2009: An 18-Year Cohort Study, Tao Zhou, Xia Li, Zhe Tang, Changchun Xie, Lixin Tao, Lei Pan, Da Huo, Fei Sun, Yanxia Luo, Wei Wang, Aoshuang Yan, Xiuhua Guo
Research outputs 2014 to 2021
Few researchers have examined the effects of multiple risk factors of cardiovascular disease (CVD) mortality simultaneously. This study was to determine the associations of combined lifestyle and other factors with CVD mortality among the elderly (n = 3,257), in Beijing, China, through data mining of the Beijing Longitudinal Study of Aging (BLSA). BLSA is a representative cohort study from 1992 to 2009, hosted by Xuan Wu Hospital. Competing risk survival analysis was conducted to explore the association between risk factors and CVD mortality. The factors focused mainly on lifestyle, physical condition, and the model was adjusted for age and gender. …
Changes In Muscle Damage Markers In Female Basketball Players, Alexandre Moreira, Ken Nosaka, Joao Antonio Nunes, Luis Viveiros, Athanasios Z. Jamurtas, Marcelo Saldanha Aoki
Changes In Muscle Damage Markers In Female Basketball Players, Alexandre Moreira, Ken Nosaka, Joao Antonio Nunes, Luis Viveiros, Athanasios Z. Jamurtas, Marcelo Saldanha Aoki
Research outputs 2014 to 2021
The aim of the present study was to investigate changes in muscle soreness, blood muscle damage markers, muscle strength and agility following an official basketball match. Eleven elite female professional basketball players (27.4 ± 4.8 years, 179.5 ± 5.5 cm, 72.0 ± 7.8 kg) of a team participated in this study. The official match was the seventh match of the season in the first phase of the Brazilian National Female Basketball Championship. Muscle soreness, plasma creatine kinase activity (CK), and myoglobin concentration (Mb) were determined before and after the match (post-match, 24 and 48 hours after the match). The 1RM …
Reporting On The Seminar - Risk Interpretation And Action (Ria): Decision Making Under Conditions Of Uncertainty, Emma E. Doyle, Shabana Khan, Carolina Adler, Ryan C. Alaniz, Simone Athayde, Kuan H. Lin, Wendy Saunders, Todd Schenk, Fabiola Sosarodriguez, Victoria Sword-Daniels, Olayinka Akanle, Marie A. Baudoin, Chiung T. Chang, Karianne D. De Bruin, Riyanti Djalante, Christine Eriksen, Hsiang C. Lee, Jyoti Mishra, Victor O. Okorie, David R. Olanya, Goda Perlaviciute, Naxhelli Ruizrivera, Suzanne Vallance, Xinlu Xie, Lun Yin, Sarah Beaven, Charles Ebikeme, Richard Eiser, David Johnston, Christine Kenney, Douglas Paton, Sarah Schweizer, Vivi Stavrou
Reporting On The Seminar - Risk Interpretation And Action (Ria): Decision Making Under Conditions Of Uncertainty, Emma E. Doyle, Shabana Khan, Carolina Adler, Ryan C. Alaniz, Simone Athayde, Kuan H. Lin, Wendy Saunders, Todd Schenk, Fabiola Sosarodriguez, Victoria Sword-Daniels, Olayinka Akanle, Marie A. Baudoin, Chiung T. Chang, Karianne D. De Bruin, Riyanti Djalante, Christine Eriksen, Hsiang C. Lee, Jyoti Mishra, Victor O. Okorie, David R. Olanya, Goda Perlaviciute, Naxhelli Ruizrivera, Suzanne Vallance, Xinlu Xie, Lun Yin, Sarah Beaven, Charles Ebikeme, Richard Eiser, David Johnston, Christine Kenney, Douglas Paton, Sarah Schweizer, Vivi Stavrou
Research outputs 2014 to 2021
The paper reports on the World Social Science (WSS) Fellows seminar on Risk Interpretation and Action (RIA), undertaken in New Zealand in December, 2013. This seminar was coordinated by the WSS Fellows program of the International Social Science Council (ISSC), the RIA working group of the Integrated Research on Disaster Risk (IRDR) program, the IRDR International Center of Excellence Taipei, the International START Secretariat and the Royal Society of New Zealand. Twenty-five early career researchers from around the world were selected to review the RIA framework under the theme of 'decision-making under conditions of uncertainty', and develop novel theoretical approaches …
An Anemia Of Alzheimer's Disease, N G. Faux, A Rembach, J Wiley, K A. Ellis, D Ames, C J. Fowler, Ralph N. Martins, K K. Pertile, R L. Rumble, B Trounson, C L. Masters, A I. Bush
An Anemia Of Alzheimer's Disease, N G. Faux, A Rembach, J Wiley, K A. Ellis, D Ames, C J. Fowler, Ralph N. Martins, K K. Pertile, R L. Rumble, B Trounson, C L. Masters, A I. Bush
Research outputs 2014 to 2021
Lower hemoglobin is associated with cognitive impairment and Alzheimer's disease (AD). Since brain iron homeostasis is perturbed in AD, we investigated whether this is peripherally reflected in the hematological and related blood chemistry values from the Australian Imaging Biomarker and Lifestyle (AIBL) study (a community-based, cross-sectional cohort comprising 768 healthy controls (HC), 133 participants with mild cognitive impairment (MCI) and 211 participants with AD). We found that individuals with AD had significantly lower hemoglobin, mean cell hemoglobin concentrations, packed cell volume and higher erythrocyte sedimentation rates (adjusted for age, gender, APOE-ε4 and site). In AD, plasma iron, transferrin, transferrin saturation …
Altered Cytological Parameters In Buccal Cells From Individuals With Mild Cognitive Impairment And Alzheimer's Disease, Maxime François, Wayne Leifert, Jane Hecker, Jeffrey Faunt, Ralph Martins, Philip Thomas, Michael Fenech
Altered Cytological Parameters In Buccal Cells From Individuals With Mild Cognitive Impairment And Alzheimer's Disease, Maxime François, Wayne Leifert, Jane Hecker, Jeffrey Faunt, Ralph Martins, Philip Thomas, Michael Fenech
Research outputs 2014 to 2021
Previous studies have shown that mild cognitive impairment (MCI) may be reflective of the early stages of more pronounced neurodegenerative disorders such as Alzheimer's disease (AD). There is a need for a minimally invasive and inexpensive diagnostic to identify those who exhibit cellular pathology indicative of MCI and AD risk so that they can be prioritized for primary preventative measures. The hypothesis was that a minimally invasive approach using cytological markers in isolated buccal mucosa cells can be used to identify individuals of both MCI and AD. An automated buccal cell assay was developed using laser scanning cytometry (LSC) to …
Young Australian Adults’ Reactions To Viewing Personalised Uv Photoaged Photographs, Lori L. Presti, Paul Chang, Myra F. Taylor
Young Australian Adults’ Reactions To Viewing Personalised Uv Photoaged Photographs, Lori L. Presti, Paul Chang, Myra F. Taylor
Research outputs 2014 to 2021
Background: Despite two nationwide sun-protection awareness campaigns, young Australian adults continue to sunbathe. Since their primary motivation for tanning is appearance enhancement, it may well be that campaigns that highlight the negative effects of tanning on appearance are more effective than campaigns that emphasise the health risks associated with sun exposure.Aims: This study aims to explore young adults’ reactions to viewing a photoaged photograph of the sun damage already visible in their facial image.Methods: Semi-structured interviews were conducted with seven females and three males aged 20-30 years. The interview transcripts were transcribed verbatim and were then subjected to Interpretive Phenomenological …
Higher Breakfast Glycaemic Load Is Associated With Increased Metabolic Syndrome Risk, Including Lower Hdl-Cholesterol Concentrations And Increased Tag Concentrations, In Adolescent Girls, Analise Nicholl, Mary Du Heaume, Trevor A. Mori, Lawrence J. Beilin, Wendy H. Oddy, Alexandra P. Bremner, Therese A. O'Sullivan
Higher Breakfast Glycaemic Load Is Associated With Increased Metabolic Syndrome Risk, Including Lower Hdl-Cholesterol Concentrations And Increased Tag Concentrations, In Adolescent Girls, Analise Nicholl, Mary Du Heaume, Trevor A. Mori, Lawrence J. Beilin, Wendy H. Oddy, Alexandra P. Bremner, Therese A. O'Sullivan
Research outputs 2014 to 2021
Almost all previous studies examining the associations between glycaemic load (GL) and metabolic syndrome risk have used a daily GL value. The daily value does not distinguish between peaks of GL intake over the day, which may be more closely associated with the risk of the metabolic syndrome. The aim of the present study was to investigate the cross-sectional associations between daily and mealtime measures of GL and metabolic syndrome risk, including metabolic syndrome components, in adolescents. Adolescents participating in the 14-year follow-up of the Western Australian Pregnancy Cohort (Raine) Study completed 3 d food records and metabolic assessments. Breakfast …
A Dynamic Evaluation Of How Kick Point Location Influences Swing Parameters And Related Launch Conditions, Christopher Joyce, Angus Burnett, Alvaro Reyes, Stephen Herbert
A Dynamic Evaluation Of How Kick Point Location Influences Swing Parameters And Related Launch Conditions, Christopher Joyce, Angus Burnett, Alvaro Reyes, Stephen Herbert
Research outputs 2014 to 2021
In golf, many parameters of the driver can be modified to maximise hitting distance. The main objective of this study was to determine whether drivers fitted with shafts having high and low kick points would alter selected swing parameters and related launch conditions. In total, 12 elite male golfers (handicap score = 1.2 ± 1.8) had three shots analysed for two drivers fitted with 'stiff' shafts with differing kick point location. Stiffness profiles of these shafts were also measured. Five swing and related launch parameters were measured using a real-time launch monitor. The locations of the low and high kick …
Overexpression Of Phospholipase A2 Group Iia In Esophageal Squamous Cell Carcinoma And Association With Cyclooxygenase-2 Expression, Yan Chun Zhai, Bin Dong, Wen Qiang Wei, Yan He, Xin Qing Li, Robert T. Cormier, Wei Wang, Fen Liu
Overexpression Of Phospholipase A2 Group Iia In Esophageal Squamous Cell Carcinoma And Association With Cyclooxygenase-2 Expression, Yan Chun Zhai, Bin Dong, Wen Qiang Wei, Yan He, Xin Qing Li, Robert T. Cormier, Wei Wang, Fen Liu
Research outputs 2014 to 2021
Background: Esophageal cancer is one of the most frequently occurring malignancies and the seventh leading cause of cancer-related deaths in the world. The esophageal squamous cell carcinoma (ESCC) is the most common histological type of esophageal cancer worldwide. Materials and Methods: Our goal in this study was to detect phospholipase A2 Group IIA (PLA2G2A) and cyclooxygenase-2 (COX-2) immuno-expression in ESCC in a high-risk population in China. Results: Positive expression of PLA2G2A protein was observed in 57.2% (166/290) of the cases, while COX-2 was found in 257 of 290 samples (88.6%), both PLA2G2A and COX-2 being expressed in 153 cases (52.8%), …
Pax Genes: Regulators Of Lineage Specification And Progenitor Cell Maintenance, Judith A. Blake, Mel R. Ziman
Pax Genes: Regulators Of Lineage Specification And Progenitor Cell Maintenance, Judith A. Blake, Mel R. Ziman
Research outputs 2014 to 2021
Pax genes encode a family of transcription factors that orchestrate complex processes of lineage determination in the developing embryo. Their key role is to specify and maintain progenitor cells through use of complex molecular mechanisms such as alternate RNA splice forms and gene activation or inhibition in conjunction with protein co-factors. The significance of Pax genes in development is highlighted by abnormalities that arise from the expression of mutant Pax genes. Here, we review the molecular functions of Pax genes during development and detail the regulatory mechanisms by which they specify and maintain progenitor cells across various tissue lineages. We …
Dystonia Type 6 Gene Product Thap1: Identification Of A 50 Kda Dna-Binding Species In Neuronal Nuclear Fractions, Maitane Ortiz-Virumbrales, Marta Ruiz, Eugene Hone, Georgia Dolios, Rong Wang, Andrika Morant, Jessica Kottwitz, Laurie J. Ozelius, Sam Gandy, Michelle Ehrlich
Dystonia Type 6 Gene Product Thap1: Identification Of A 50 Kda Dna-Binding Species In Neuronal Nuclear Fractions, Maitane Ortiz-Virumbrales, Marta Ruiz, Eugene Hone, Georgia Dolios, Rong Wang, Andrika Morant, Jessica Kottwitz, Laurie J. Ozelius, Sam Gandy, Michelle Ehrlich
Research outputs 2014 to 2021
Mutations in THAP1 result in dystonia type 6, with partial penetrance and variable phenotype. The goal of this study was to examine the nature and expression pattern of the protein product(s) of the Thap1 transcription factor (DYT6 gene) in mouse neurons, and to study the regional and developmental distribution, and subcellular localization of Thap1 protein. The goal was accomplished via overexpression and knock-down of Thap1 in the HEK293T cell line and in mouse striatal primary cultures and western blotting of embryonic Thap1-null tissue. The endogenous and transduced Thap1 isoforms were characterized using three different commercially available anti-Thap1 antibodies and validated …
The Global Obesity Epidemic Is Related To Stroke, Dementia And Alzheimer's Disease, Ian J. Martins
The Global Obesity Epidemic Is Related To Stroke, Dementia And Alzheimer's Disease, Ian J. Martins
Research outputs 2014 to 2021
The global epidemic in obesity and diabetes has affected individuals in both the developing and developed world with the global death rate (63%) related to chronic diseases with 35% attributed to cardiovascular disease and stroke, 21 % to cancer and 12 % to chronic respiratory disease. The interest in connections between the global stroke epidemic, dementia and Alzheimer’s disease (AD) has increased with hypertension, smoking, diabetes, obesity, poor diet, physical inactivity, atrial fibrillation, excessive alcohol consumption, abnormal lipid profile and psychosocial stress/depression implicated in their pathogenesis. The connection between stroke and AD is possibly related to the low adiponectin and …
The Effect Of Double-Blind Carbohydrate Ingestion During 60 Km Of Self-Paced Exercise In Warm Ambient Conditions, Camila Nassif, Aline R. Gomes, Gustavo H.C. Peixoto, Mauro H. Chagas, Danusa D. Soares, Emerson Silami-Garcia, Eric J. Drinkwater, Jack Cannon, Frank E. Marino
The Effect Of Double-Blind Carbohydrate Ingestion During 60 Km Of Self-Paced Exercise In Warm Ambient Conditions, Camila Nassif, Aline R. Gomes, Gustavo H.C. Peixoto, Mauro H. Chagas, Danusa D. Soares, Emerson Silami-Garcia, Eric J. Drinkwater, Jack Cannon, Frank E. Marino
Research outputs 2014 to 2021
This study evaluated double blind ingestions of placebo (PLA) versus 6% carbohydrate (CHO) either as capsules (c) or beverage (b) during 60 km self-paced cycling in the heat (32C and 50% relative humidity).
“Keeping It Together, Keeping Their Heads Above Water”: Western Australian Child Health Nurses’ Understanding Of Resilience In Postpartum Mothers, Rachael O. Collins, Julie Ann Pooley, Myra F. Taylor
“Keeping It Together, Keeping Their Heads Above Water”: Western Australian Child Health Nurses’ Understanding Of Resilience In Postpartum Mothers, Rachael O. Collins, Julie Ann Pooley, Myra F. Taylor
Research outputs 2014 to 2021
Assessing the well-being of postpartum mothers is an important aspect of postnatal nursing care. For this reason, Child Health Nurses (CHNs) are charged with the responsibility of identifying postpartum mothers who do/not manifest resilient behavioral qualities. However, little is known about CHNs’ conceptualization of resilience or how they assess resilience in postpartum mothers. This exemplar study addressed this knowledge shortfall by conducting semi-structured interviews with eight practicing CHNs. The study’s findings reveal that although CHNs’ conceptual understanding of resilience is congruent with current theoretical thinking, some variance does exist in the ways in which CHNs assess postpartum resilience, particularly, in …
Selection Of An Instrument To Evaluate The Organizational Environment Of Nurses Working In Intensive Care: An Integrative Review, Brett Abbenbroek, Christine M. Duffield, Doug Elliot
Selection Of An Instrument To Evaluate The Organizational Environment Of Nurses Working In Intensive Care: An Integrative Review, Brett Abbenbroek, Christine M. Duffield, Doug Elliot
Research outputs 2014 to 2021
To determine an appropriate survey instrument to evaluate the impact of organizational structures on the work environment of intensive care nurses.
Induction Of Nafld With Increased Risk Of Obesity And Chronic Diseases In Developed Countries, Ian J. Martins
Induction Of Nafld With Increased Risk Of Obesity And Chronic Diseases In Developed Countries, Ian J. Martins
Research outputs 2014 to 2021
The susceptibility of individuals to obesity has been reported in many developed countries with predisposition of humans to obesity associated with high calorie diets and unhealthy lifestyles. Obesity may closely be involved in cell suicide in various organ diseases with the importance of accelerated aging that requires early intervention with drug therapy to prevent diseases such as non alcoholic fatty liver disease (NAFLD) that has increased in children and reached to approx. 40% of the global population. Obesity is induced by various diets and lifestyle factors such as stress, anxiety and depression which are important to consider with the global …
Traditional Chinese Medicine And New Concepts Of Predictive, Preventive And Personalized Medicine In Diagnosis And Treatment Of Suboptimal Health, Wei Wang, Alyce C. Russell, Yuxiang Yan
Traditional Chinese Medicine And New Concepts Of Predictive, Preventive And Personalized Medicine In Diagnosis And Treatment Of Suboptimal Health, Wei Wang, Alyce C. Russell, Yuxiang Yan
Research outputs 2014 to 2021
The premise of disease-related phenotypes is the definition of the counterpart normality in medical sciences. Contrary to clinical practices that can be carefully planned according to clinical needs, heterogeneity and uncontrollability is the essence of humans in carrying out health studies. Full characterization of consistent phenotypes that define the general population is the basis to individual difference normalization in personalized medicine. Self-claimed normal status may not represent health because asymptomatic subjects may carry chronic diseases at their early stage, such as cancer, diabetes mellitus and atherosclerosis. Currently, treatments for non-communicable chronic diseases (NCD) are implemented after disease onset, which is …
A Process-Oriented Measure Of Habit Strength For Moderate-To-Vigorous Physical Activity, J. Robert Grove, Irja Zillic, Nikola Medic
A Process-Oriented Measure Of Habit Strength For Moderate-To-Vigorous Physical Activity, J. Robert Grove, Irja Zillic, Nikola Medic
Research outputs 2014 to 2021
Habitual action is an important aspect of health behaviour, but the relevance of various habit strength indicators continues to be debated. This study focused specifically on moderate-to-vigorous physical activity (MVPA) and evaluated the construct validity of a framework emphasizing patterned action, stimulus-response bonding, automaticity, and negative consequences for nonperformance as indicators of habit strength for this form of exercise. Methods: Upper-level undergraduates (N = 124) provided demographic information and responded to questionnaire items assessing historical MVPA involvement, current MVPA involvement, and the four proposed habit strength dimensions. Factor analyses were used to examine the latent structure of the habit strength …
Development Of A Patient-Administered Self-Assessment Tool (Satp) For Follow-Up Of Colorectal Cancer Patients In General Practice, Irene M. Ngune, Moyez Jiwa, Alexandra Mcmanus, Jeff Hughes, Richard Parsons, Rupert Hodder, Fiona Entriken
Development Of A Patient-Administered Self-Assessment Tool (Satp) For Follow-Up Of Colorectal Cancer Patients In General Practice, Irene M. Ngune, Moyez Jiwa, Alexandra Mcmanus, Jeff Hughes, Richard Parsons, Rupert Hodder, Fiona Entriken
Research outputs 2014 to 2021
Background: Treatment for colorectal cancer (CRC) may result in physical, social, and psychological needs that affect patients’ quality of life post-treatment. A comprehensive assessment should be conducted to identify these needs in CRC patients post treatment, however, there is a lack of tools and processes available in general practice. Aims: This study aimed to develop a patient-completed needs screening tool that identifies potentially unmet physical, psychological, and social needs in CRC and facilitates consultation with a general practitioner (GP) to address these needs. Methods: The development of the self-assessment tool for patients (SATp) included a review of the literature; face …
Influence Of Race Distance And Biological Sex On Age-Related Declines In Triathlon Performance. Part A, Sam Shi Xuan Wu, Jeremiah Peiffer, Jeanick Brisswalter, Wing Y. Lau, Kazunori Nosaka, Chris R. Abbiss
Influence Of Race Distance And Biological Sex On Age-Related Declines In Triathlon Performance. Part A, Sam Shi Xuan Wu, Jeremiah Peiffer, Jeanick Brisswalter, Wing Y. Lau, Kazunori Nosaka, Chris R. Abbiss
Research outputs 2014 to 2021
This study examined the effect of biological sex and race distance on the age-related declines in swimming, cycling, running and overall performances of the sprint, Olympic, Half-Ironman and Ironman triathlons. Individual discipline and overall performance time of the top 20% non-elite males (n=468) and females (n=146) were compared by categorizing into four 10-year age-groups (20-29, 30-39, 40-49, 50+ years) and normalising to the mean performance time of the fastest age-group for each race. An earlier, larger and faster rate of decline (p=0.01) in performance with ageing was observed in females (≥30 years, 9.3%, 3.0% per decade respectively) and males (≥40 …
Developing And Validating A Healthcare Information Security Governance Framework, Rachel J. Mahncke, Patricia A. Williams
Developing And Validating A Healthcare Information Security Governance Framework, Rachel J. Mahncke, Patricia A. Williams
Research outputs 2014 to 2021
General medical practices' in Australia are vulnerable to information security threats and insecure practices. It is well accepted in the healthcare environment that information security is both a technical and a human endeavour, and that the human behaviours, particularly around integration with healthcare workflow, are key barriers to good information security practice. The Royal Australian College of General Practitioner's (RACGP) Computer and Information Security Standards (CISS) 2013 are the best practice standards for general practices, against which information security is assessed during practice accreditation. With the release of ISO/IEC 27014:2013 Information technology - Security techniques - Governance of information security …
Changing Places: The Need To Alter The Start Point For Information Security Design, Elizabeth Coles-Kemp, Patricia A. Williams
Changing Places: The Need To Alter The Start Point For Information Security Design, Elizabeth Coles-Kemp, Patricia A. Williams
Research outputs 2014 to 2021
Information security is a necessary requirement of information sharing within an electronic health system because without it confidentiality, availability, or integrity controls are absent. Research shows that the application of security in this setting is subject to workarounds partly because of resistance to security controls from clinicians who feel that their voice is excluded from the security design process. Heeks' explored the nature of health system design and referred to the distance between system designer and practitioner as the 'design-reality gap'. To reduce this gap, systems designers typically deploy usercentred, participatory approaches to design. They use various forms of consultation …
Principles Of Practice In Mental Health Assessment With Aboriginal Australians, Yolonda Adams, Neil M. Drew, Roz Walker
Principles Of Practice In Mental Health Assessment With Aboriginal Australians, Yolonda Adams, Neil M. Drew, Roz Walker
Research outputs 2014 to 2021
In this chapter, concepts and history of assessment and testing in the context of Aboriginal and Torres Strait Islander social and emotional wellbeing and mental health are discussed. Importantly, recently revised diagnostic guidelines and the National Practice Standards for the Mental Health Workforce 20131 and their appropriateness for meeting the distinctive needs of Aboriginal people are reviewed. Various assessment tools and measures that have been validated or proved appropriate for use with particular Aboriginal populations, i.e. youth, women and older people, are described. We conclude that practitioners need to be critically reflective in their role in assessment, and position themselves …
Serum Concentrations Of The Biomarkers Ca125, Ca15-3, Ca72-4, Tpsa And Papp-A In Natural And Stimulated Ovarian Cycles, Melissa J. Stemp, Peter Roberts, Allison Mcclements, Vincent Chapple, Jay Natalwala, Michael L. Black, Phillip L. Matson
Serum Concentrations Of The Biomarkers Ca125, Ca15-3, Ca72-4, Tpsa And Papp-A In Natural And Stimulated Ovarian Cycles, Melissa J. Stemp, Peter Roberts, Allison Mcclements, Vincent Chapple, Jay Natalwala, Michael L. Black, Phillip L. Matson
Research outputs 2014 to 2021
Objective: Biomarkers associated with cancer screening (CA125, CA15-3, CA72-4, total prostate specific antigen [tPSA]) and the monitoring of pregnancy (pregnancy associated plasma protein-A [PAPP-A]) were measured during natural and stimulated ovarian cycles in disease-free non-pregnant women to determine if they could reflect normal events relating to ovulation and/or endometrial changes. Methods: A total of 73 blood samples (10 women) collected throughout the natural menstrual cycle, and 64 blood samples (11 women) taken during stimulated ovarian cycles, were analysed on the Roche Cobas e411 automated analyser. Results: Detectable levels of tPSA were measured in at least one point in the cycle …
En Attendant Centiloid, Victor L. Villemagne, Vincent Doré, Paul Yates, Belinda Brown, Rachel Mulligan, Pierrick Bourgeat, Robyn Veljanoski, Stephanie R. Rainey-Smith, Kevin Ong, Alan Rembach, Robert Williams, Samantha C. Burnham, Simon Laws, Olivier Salvado, Kevin Taddei, S. L. Macaulay, Ralph Martins, David Ames, Colin L. Masters, Christopher C. Rowe
En Attendant Centiloid, Victor L. Villemagne, Vincent Doré, Paul Yates, Belinda Brown, Rachel Mulligan, Pierrick Bourgeat, Robyn Veljanoski, Stephanie R. Rainey-Smith, Kevin Ong, Alan Rembach, Robert Williams, Samantha C. Burnham, Simon Laws, Olivier Salvado, Kevin Taddei, S. L. Macaulay, Ralph Martins, David Ames, Colin L. Masters, Christopher C. Rowe
Research outputs 2014 to 2021
Aims: Test the robustness of a linear regression transformation of semiquantitative values from different Aβ tracers into a single continuous scale. Study Design: Retrospective analysis. Place and Duration of Study: PET imaging data acquired in Melbourne and Perth, Australia, between August 2006 and May 2014. Methodology: Aβ imaging in 633 participants was performed with four different radiotracers: flutemetamol (n=267), florbetapir (n=195), florbetaben (n=126) and NAV4694 (n=45). SUVR were generated with the methods recommended for each tracer, and classified as high (Aβ+) or low (Aβ-) based on their respective thresholds. Linear regression transformation based on reported head-to-head comparisons of each tracer …
Social Engagement, Setting And Alcohol Use Among A Sample Of Older Australians, Julie Dare, Celia Wilkinson, Steve Allsop, Stacey Waters, Sheila Mchale
Social Engagement, Setting And Alcohol Use Among A Sample Of Older Australians, Julie Dare, Celia Wilkinson, Steve Allsop, Stacey Waters, Sheila Mchale
Research outputs 2014 to 2021
The harms associated with risky alcohol consumption have long been researched and recognised in the health field. However, little available research has focused on older people, or extended analysis of alcohol use by this segment of the population beyond a bio-medical perspective. With the rapid ageing of the global population, research that investigates alcohol use amongst older people from a social perspective is important. This article reports on research with a group of older women and men, to identify and explain factors that influence alcohol consumption. In-depth interviews were conducted in Perth, Western Australia with 20 men and 22 women …
Hypoxia Alters Expression Of Zebrafish Microtubule-Associated Protein Tau (Mapta, Maptb) Gene Transcripts, Seyyed H. Moussavi Nik, Morgan Newman, Swamynathan Ganesan, Mengqi Chen, Ralph Martins, Giuseppe Verdile, Michael Lardelli
Hypoxia Alters Expression Of Zebrafish Microtubule-Associated Protein Tau (Mapta, Maptb) Gene Transcripts, Seyyed H. Moussavi Nik, Morgan Newman, Swamynathan Ganesan, Mengqi Chen, Ralph Martins, Giuseppe Verdile, Michael Lardelli
Research outputs 2014 to 2021
Background: Microtubule-associated protein tau (MAPT) is abundant in neurons and functions in assembly and stabilization of microtubules to maintain cytoskeletal structure. Human MAPT transcripts undergo alternative splicing to produce 3R and 4R isoforms normally present at approximately equal levels in the adult brain. Imbalance of the 3R-4R isoform ratio can affect microtubule binding and assembly and may promote tau hyperphosphorylation and neurofibrillary tangle formation as seen in neurodegenerative diseases such as frontotemporal dementia (FTD) and Alzheimer's disease (AD). Conditions involving hypoxia such as cerebral ischemia and stroke can promote similar tau pathology but whether hypoxic conditions cause changes in MAPT …