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Medicine and Health Sciences Commons

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Research outputs 2014 to 2021

Series

2020

Major clinical study

Articles 1 - 5 of 5

Full-Text Articles in Medicine and Health Sciences

Elecsys Csf Biomarker Immunoassays Demonstrate Concordance With Amyloid-Pet Imaging, James A. Doecke, Larry Ward, Samantha C. Burnham, Victor L. Villemagne, Qiao-Xin Li, Steven Collins, Christopher J. Fowler, Ekaterina Manuilova, Monika Widmann, Stephanie R. Rainey-Smith, Ralph N. Martins, Colin L. Masters, Aibl Research Group Jan 2020

Elecsys Csf Biomarker Immunoassays Demonstrate Concordance With Amyloid-Pet Imaging, James A. Doecke, Larry Ward, Samantha C. Burnham, Victor L. Villemagne, Qiao-Xin Li, Steven Collins, Christopher J. Fowler, Ekaterina Manuilova, Monika Widmann, Stephanie R. Rainey-Smith, Ralph N. Martins, Colin L. Masters, Aibl Research Group

Research outputs 2014 to 2021

Background: β-amyloid (Aβ) positron emission tomography (PET) imaging is currently the only Food and Drug Administration-approved method to support clinical diagnosis of Alzheimer's disease (AD). However, numerous research studies support the use of cerebrospinal fluid (CSF) biomarkers, as a cost-efficient, quick and equally valid method to define AD pathology. Methods: Using automated Elecsys® assays (Roche Diagnostics) for Aβ (1-42) (Aβ42), Aβ (1-40) (Aβ40), total tau (tTau) and phosphorylated tau (181P) (pTau), we examined CSF samples from 202 participants of the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of ageing cohort, to demonstrate the concordance with pathological AD via PET imaging. …


Should The Pbl Tutor Be Present? A Cross-Sectional Study Of Group Effectiveness In Synchronous And Asynchronous Settings, Samuel Edelbring, Siw Alehagen, Evalotte Mörelius, Annakarin Johansson, Patrik Rytterström Jan 2020

Should The Pbl Tutor Be Present? A Cross-Sectional Study Of Group Effectiveness In Synchronous And Asynchronous Settings, Samuel Edelbring, Siw Alehagen, Evalotte Mörelius, Annakarin Johansson, Patrik Rytterström

Research outputs 2014 to 2021

Background: The tutorial group and its dynamics are a cornerstone of problem-based learning (PBL). The tutor's support varies according to the setting, and it is pertinent to explore group effectiveness in relation to different settings, for example online or campus-based. The PBL groups' effectiveness can partly be assessed in terms of cognitive and motivational aspects, using a self-report tool to measure PBL group effectiveness, the Tutorial Group Effectiveness Instrument (TGEI). This study's aim was to explore tutor participation in variations of online and campus-based tutorial groups in relation to group effectiveness. A secondary aim was to validate a tool for …


First Age- And Gender-Matched Case-Control Study In Australia Examining The Possible Association Between Toxoplasma Gondii Infection And Type 2 Diabetes Mellitus: The Busselton Health Study, Aus Molan, Kazunori Nosaka, Michael Hunter, Jinxia Zhang, Xiaoni Meng, Manshu Song, Wei Wang Jan 2020

First Age- And Gender-Matched Case-Control Study In Australia Examining The Possible Association Between Toxoplasma Gondii Infection And Type 2 Diabetes Mellitus: The Busselton Health Study, Aus Molan, Kazunori Nosaka, Michael Hunter, Jinxia Zhang, Xiaoni Meng, Manshu Song, Wei Wang

Research outputs 2014 to 2021

An emerging field of research is starting to examine the association of infectious pathogens with type 2 diabetes mellitus (T2DM). An understudied parasite of interest is Toxoplasma gondii. Globally, very few studies have been conducted to investigate this association. Additionally, very little data exists on the prevalence of T. gondii in the general Australian population. Our group sought to determine the prevalence, association, and risk factors between T. gondii infection and T2DM from a representative Australian human population. Through a cross-sectional, age-A nd gender-matched case-control study, 150 subjects with T2DM together with 150 control subjects from the Busselton Health Study …


Definitions, Sources And Self-Reported Consumption Of Regionally Grown Fruits And Vegetables In Two Regions Of Australia, Katherine Kent, Stephanie Godrich, Sandra Murray, Stuart Auckland, Lauren Blekkenhorst, Beth Penrose, Johnny Lo, Amanda Devine Jan 2020

Definitions, Sources And Self-Reported Consumption Of Regionally Grown Fruits And Vegetables In Two Regions Of Australia, Katherine Kent, Stephanie Godrich, Sandra Murray, Stuart Auckland, Lauren Blekkenhorst, Beth Penrose, Johnny Lo, Amanda Devine

Research outputs 2014 to 2021

Regional food systems are complex networks, with numerous retail sources that underpin a local economy. However, evidence is limited regarding how consumers define, identify, and source regionally grown fresh fruits and vegetables (RGFFV). A cross-sectional study was conducted in Tasmania (TAS) and South Western Australia (SWA) to compare how RGFFV are defined, identified and sourced by consumers, including self-reported consumption of selected RGFFV. Survey data were analyzed using the Chi-square test and t-tests. Results (TAS n = 120, SWA n = 123) identified that consumers had mixed perceptions of how RGFFV are defined, including produce sold at farmers markets, or …


South West Food Community: How Government And Community Initiatives Are Supporting Systemic Change Towards Enhanced Food Security, Stephanie Louise Godrich, Melissa Stoneham, Melinda Edmunds, Amanda Devine Jan 2020

South West Food Community: How Government And Community Initiatives Are Supporting Systemic Change Towards Enhanced Food Security, Stephanie Louise Godrich, Melissa Stoneham, Melinda Edmunds, Amanda Devine

Research outputs 2014 to 2021

Objective: Food security refers to adequate physical, social and economic access to food and is regarded as a complex, ‘wicked’ issue. This research aimed to understand the perspectives of initiative leaders (stakeholders), regarding their project relating to food security and its possession of characteristics associated with system change to enhance food security. Methods: Stakeholders (n=51) participated in semi-structured interviews that evaluated initiatives (n=52) against 36 desirable characteristics for system change. Transcripts were analysed using QSR NVivo and Wicked Lab’s Tool for Systemic Change. Results: Community-based initiatives often harnessed the passion of local communities to enhance food security through awareness-raising activities …