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Enhanced Skeletal Muscle Ribosome Biogenesis, Yet Attenuated Mtorc1 And Ribosome Biogenesis-Related Signalling, Following Short-Term Concurrent Versus Single-Mode Resistance Training, Jackson J. Fyfe, David J. Bishop, Jonathan D. Bartlett, Erik D. Hanson, Mitchell J. Anderson, Andrew P. Garnham, Nigel K. Stepto

Research outputs 2014 to 2021

Combining endurance training with resistance training (RT) may attenuate skeletal muscle hypertrophic adaptation versus RT alone; however, the underlying mechanisms are unclear. We investigated changes in markers of ribosome biogenesis, a process linked with skeletal muscle hypertrophy, following concurrent training versus RT alone. Twenty-three males underwent eight weeks of RT, either performed alone (RT group, n = 8), or combined with either high-intensity interval training (HIT+RT group, n = 8), or moderate-intensity continuous training (MICT+RT group, n = 7). Muscle samples (vastus lateralis) were obtained before training, and immediately before, 1 h and 3 h after the final training session. …