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Prevalence And Molecular Epidemiology Of Clostridium Difficile Infection In Indonesia, Deirdre Collins, M. H. Gasem, T. H. Habibie, I. G. Arinton, P. Hendriyanto, A. P. Hartana, T. V. Riley

Research outputs 2014 to 2021

Clostridium difficile has not been studied in detail in Asia, particularly Southeast Asia. We thus performed a prevalence study across four hospitals in Central Java province, Indonesia. Stool samples were collected from patients with diarrhoea and tested by enzyme immunoassay for glutamate dehydrogenase (GDH) and toxin A/B (C DIFF QUIK CHEK COMPLETE, TechLab). Specimens were cultured and molecular typing was performed. In total, 340 samples were tested, of which 70 (20.6%) were GDH positive, with toxin detected in 19 (5.6%). Toxigenic C. difficile was isolated from 37 specimens (10.9%), while a further 36 (10.6%) nontoxigenic isolates were identified. The most …