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Full-Text Articles in Medicine and Health Sciences
Clinical Decision-Making Tools: How Effective Are They In Improving The Quality Of Health Care?, Lyndal Trevana, Kirsten Mccaffery, Glenn Salkeld, Paul Glasziou, Chris Del Mar, Jenny A. Doust, Tammy Hoffmann
Clinical Decision-Making Tools: How Effective Are They In Improving The Quality Of Health Care?, Lyndal Trevana, Kirsten Mccaffery, Glenn Salkeld, Paul Glasziou, Chris Del Mar, Jenny A. Doust, Tammy Hoffmann
Paul Glasziou
Exec Summary Clinical decision-making tools can be considered in two broad categories – those designed to be used by clinicians and those designed to promote shared decision making with the clinician and patient together. The potential effect of computerised clinical decision support systems (CDSS) on variations in practice is not well understood, and CDSS are currently not a recommended means of improving evidence-based practice, or patient outcomes, since the mechanisms of success and failure are not well defined and the potential impact on workflows and adverse events are poorly evaluated. Despite numerous randomised controlled trials, there is poor quality evidence …
Searching For Randomized Controlled Trials And Systematic Reviews On Exercise: A Descriptive Study, Antonio Jose Grande, Tammy Hoffmann, Paul Glasziou
Searching For Randomized Controlled Trials And Systematic Reviews On Exercise: A Descriptive Study, Antonio Jose Grande, Tammy Hoffmann, Paul Glasziou
Paul Glasziou
The current paradigm of science is to accumulate as much research data as possible, with less thought given to navigation or synthesis of the resulting mass, which hampers locating and using the research. The aim here was to describe the number of randomized controlled trials (RCTs) and systematic reviews (SRs) focusing on exercise, and their journal sources, that have been indexed in PubMed over time. DESIGN AND SETTING: Descriptive study conducted at Bond University, Australia. METHOD: To find RCTs, a search was conducted in PubMed Clinical Queries, using the category “Therapy” and the Medical Subject Headings (MeSH) term “Exercise”. To …
Which Lipid Measurement Should We Monitor? An Analysis Of The Lipid Study, Paul Glasziou, Les Irwig, Adrienne Kirby, Andrew Tonkin, R J. Simes
Which Lipid Measurement Should We Monitor? An Analysis Of The Lipid Study, Paul Glasziou, Les Irwig, Adrienne Kirby, Andrew Tonkin, R J. Simes
Paul Glasziou
Objectives: To evaluate the optimal lipid to measure in monitoring patients, we assessed three factors that influence the choice of monitoring tests: (1) clinical validity; (2) responsiveness to therapy changes and (3) the size of the long-term ‘signal-to-noise’ ratio. Design: Longitudinal analyses of repeated lipid measurement over 5 years. Setting: Subsidiary analysis of a Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) study—a clinical trial in Australia, New Zealand and Finland. Participants: 9014 patients aged 31–75 years with previous acute coronary syndromes. Interventions: Patients were randomly assigned to 40 mg daily pravastatin or placebo. Primary and secondary outcome measures: We …