Medicine and Health Sciences Commons^™

Is It Coincidence Or Consequence For A Case With Antiphospholipid Antibody Syndrome Overlapping Sle To Develop An Immune Complex Nephropathy Followed By A Nonimmune Complex Podocytopathy?, Jinil Yoo, Hugo Villanueva, Manimaran Kaliamurthy, John Kang, Lin Lwin

NYMC Residents/Fellows Publications

Antiphospholipid antibody syndrome (APS) may occur in a primary form or in association with SLE and seldom presents with nephrotic syndrome (NS). We present a case with APS who developed recurrent NS 6 years apart. The first episode of NS occurred with biopsy findings consistent with lupus nephritis (LN) class V (membranous) with no clear evidence of SLE, and responded to a remission with steroids and MMF. On the 2(nd) episode, the biopsy revealed negative immunofluorescent (IF) study for immune complexes and EM findings of complete effacement of foot processes and acellular debris in thickened capillary walls, compatible with healed …