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Menoufia Medical Journal

Leprosy

Publication Year

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

Serum Levels Of Anticeramide Antibodies, Interleukin-4, And Tumor Necrosis Factor In Newly Diagnosed Egyptian Patients With Leprosy, Eman M. A. El Gayed, Heba A. S. Bazid, Hesham N. Khaled, Hoda A. Bassiouny, Mohammed I. Mostafa Apr 2022

Serum Levels Of Anticeramide Antibodies, Interleukin-4, And Tumor Necrosis Factor In Newly Diagnosed Egyptian Patients With Leprosy, Eman M. A. El Gayed, Heba A. S. Bazid, Hesham N. Khaled, Hoda A. Bassiouny, Mohammed I. Mostafa

Menoufia Medical Journal

Objective The aim was to estimate the serum levels of anticeramide antibodies (ACAs), interleukin-4 (IL-4), and tumor necrosis factor (TNF) in patients with leprosy and their possible role in the anticipation of leprosy complications. Background Leprosy is a disease that primarily involves the peripheral nerves and skin. Nerve damage is concomitant with multibacillary (MB) leprosy, and as ceramide is an element of the myelin sheath, ACAs can be a marker in the nerve destruction evaluation. Cytokine estimation can anticipate inflammation instigated by infections or trauma. The authors aimed to detect the role of serum levels of ACA, IL-4, and TNF-α …


Relation Between Anti-Phenolic Glycolipid-1 Seropositivity And Other Factors Among The Household Contacts Of Egyptian Leprosy Cases, Dalia M. Abdou, Magda M. Hagag, Manal A. Safan Mar 2019

Relation Between Anti-Phenolic Glycolipid-1 Seropositivity And Other Factors Among The Household Contacts Of Egyptian Leprosy Cases, Dalia M. Abdou, Magda M. Hagag, Manal A. Safan

Menoufia Medical Journal

Objective The aim of this study was to evaluate the relationship between anti-phenolic glycolipid-1 (anti-PGL-1) seropositivity and the presence of other risk factors and signs suggestive of leprosy in household contacts (HCC) of leprosy cases. Objective Leprosy is a chronic infectious disease. Its prevalence has declined after the introduction of multidrug therapy; however, efforts are needed for early case identification. Relation of anti-PGL-1 antibody (Ab) levels in HCC and other risk factors is a point of concern. Patients and methods In this cross-sectional study, we studied serum anti-PGL-1 Ab levels among 90 HCC of leprosy cases that were reported during …