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Full-Text Articles in Medicine and Health Sciences
Does Beclin 1 Have A Role In Basal Cell Carcinoma?, Alaa H. Marey, Dania N. Abo Elros, Rehab M. Samaka, Tarek M. Rageh
Does Beclin 1 Have A Role In Basal Cell Carcinoma?, Alaa H. Marey, Dania N. Abo Elros, Rehab M. Samaka, Tarek M. Rageh
Menoufia Medical Journal
Objective To evaluate the role of Beclin 1 in basal cell carcinoma (BCC). Background BCC is the most common kind of skin cancer with increased incidence. Autophagy is considered an intracellular homeostatic pathway that is related to cancer and other diseases. Beclin 1 is a specific marker for autophagy. Patients and methods This An Ambidirectional Cohort Study was conducted on 77 cases with BCC and 20 age-matched and sex-matched apparently healthy participants. All sections were immunohistochemical stained for Beclin 1 antibody. Results Significant absolute Beclin 1 cytoplasmic localization in epidermis and dermis of control group was noted, whereas in BCC, …
Surgical Management Of Nonmelanomatous Malignant Cutaneous Lesions Of The Face, Ahmed S. El-Gammal, Ibrahim M. Zeitoun, Mahmoud A. E. Oda, Soliman A. El-Shakhs, Yasser M. El-Sheikh
Surgical Management Of Nonmelanomatous Malignant Cutaneous Lesions Of The Face, Ahmed S. El-Gammal, Ibrahim M. Zeitoun, Mahmoud A. E. Oda, Soliman A. El-Shakhs, Yasser M. El-Sheikh
Menoufia Medical Journal
Objective The aim of the present study was to evaluate the esthetic and functional outcomes after surgical excision of nonmelanomatous malignant lesions of the face, followed by a suitable tool of reconstruction. Background Neoplasm of the skin is found most often on the face. Cosmetically, the face is the most important anatomic area for most patients. Because of this, malignant tumors of the facial skin pose a great challenge in treatment, prohibiting compromises between oncologically responsible surgery and functional and cosmetic outcomes. Patients and methods This prospective study included 25 patients, all of them suffering from nonmelanomatous skin cancer and …