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A Prospective Cohort Study Comparing The Reactogenicity Of Trivalent Influenza Vaccine In Pregnant And Non-Pregnant Women, A Regan, L Tracey, C Blyth, D Mak, P Richmond, G Shellam, C Talbot, P Effler
A Prospective Cohort Study Comparing The Reactogenicity Of Trivalent Influenza Vaccine In Pregnant And Non-Pregnant Women, A Regan, L Tracey, C Blyth, D Mak, P Richmond, G Shellam, C Talbot, P Effler
Medical Papers and Journal Articles
Background: Influenza vaccination during pregnancy can prevent serious illness in expectant mothers and provide protection to newborns; however, historically uptake has been limited due to a number of factors, including safety concerns. Symptomatic complaints are common during pregnancy and may be mistakenly associated with reactions to trivalent influenza vaccine (TIV). To investigate this, we compared post-vaccination events self-reported by pregnant women to events reported by non-pregnant women receiving TIV.
Methods: A prospective cohort of 1,086 pregnant women and 314 non-pregnant female healthcare workers (HCWs) who received TIV between March-May 2014 were followed-up seven days post-vaccination to assess local and systemic …