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Full-Text Articles in Medicine and Health Sciences
Social Dominance Alters Stress-Induced Neural Activity And Generates Individual Differences In Stress Vulnerability, Jenna Lee Laymon
Social Dominance Alters Stress-Induced Neural Activity And Generates Individual Differences In Stress Vulnerability, Jenna Lee Laymon
Masters Theses
Identifying the physiological and behavioral mechanisms that underlie stress vulnerability is a crucial step toward identifying novel targets for the prevention and treatment of stress-related disorders. Social status is a key environmental factor that contributes to individual variations in stress vulnerability. In particular, achieving a subordinate social status has been shown to produce susceptibility to anxiety-like and depressive-like behavior. In this project, our aim was to identify neural ensembles regulating how dominance status modulated stress-induced changes in avoidant behavior in male and female Syrian hamsters. Using a viral vector that codes for robust activity marker (RAM), we investigated whether stress-induced …
Differential Microglial Activation Following Immune Challenge In Peripubertal And Adult Outbred Mice, David J. Placzek
Differential Microglial Activation Following Immune Challenge In Peripubertal And Adult Outbred Mice, David J. Placzek
Masters Theses
Pubertal development is a time of growth and development in the brain, leading to high sensitivity during this period. Past research in our lab has shown that shipping female inbred and outbred mice during pubertal development alters their sensitivity to steroid hormones in adulthood, thus affecting sexual receptivity, cognition, depression-like behavior, and anxiety-like behavior. Here, we test the hypothesis that mice treated with lipopolysaccharide during pubertal development would have more active microglia, the brain's immune cells, after injection than mice treated with lipopolysaccharide in adulthood. No significant interactions were observed between treatment and age between any brain area measured, suggesting …
Validation Of The Masculine Gender Role Stress Scale In A Diverse Population, Amanda Eliza Sherman
Validation Of The Masculine Gender Role Stress Scale In A Diverse Population, Amanda Eliza Sherman
Masters Theses
Adherence to traditional masculinity has been associated with negative physical and psychological health outcomes. Specifically, the standards of masculinity imposed on men have been associated with high levels of stress reactivity, interpersonal violence, and substance abuse. However, previous research has been limited to primarily Caucasian samples. In order to better understand masculinity and the stress associated with adherence to masculinity across ethnicity, we examined the validity of the Masculine Gender Role Stress scale in a diverse sample. We hypothesized that the MGRS in a diverse sample would function similarly to the MGRS in a primarily Caucasian sample in that it …