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A Novel Exo-Proteomic Approach To The Study Of Traumatic Brain Injury, Ron B. Moyron Sep 2018

A Novel Exo-Proteomic Approach To The Study Of Traumatic Brain Injury, Ron B. Moyron

Loma Linda University Electronic Theses, Dissertations & Projects

Concussions and Traumatic Brain Injuries (TBI) are significant health concerns and affect a wide cross section of society. Current diagnostic criteria and modalities, such as brain imaging and subjective measures of consciousness such as the Glasgow Coma Scale (GCS) score, are insufficient to properly diagnose the full spectrum of head injuries. Assessment of injury severity and outcome are further complicated by the vast array of symptoms, many of which mimic those displayed by other disorders. It is important to possess a better diagnostic tool for head injury triage and outcome prediction. One current line of inquiry seeks to discover a …


Neurocognitive And Psychosocial Effects Of Repeated Concussions In Children And Adolescents, Shina Halavi Jun 2018

Neurocognitive And Psychosocial Effects Of Repeated Concussions In Children And Adolescents, Shina Halavi

Loma Linda University Electronic Theses, Dissertations & Projects

In the United States, an estimated 1.7 million people sustain a traumatic brain injury (TBI) annually. About 75% of these TBIs are mild, which are referred to as “concussions.” This study assessed the neurocognitive and psychosocial effects of repeated concussions in children and adolescents and their interactions with age and gender. It also assessed the correlation between psychosocial functioning and neurocognitive functioning. Given the paucity of research on the effects of concussion in the developing brain, the current study characterized the neurocognitive and psychosocial effects of concussion in young populations. The overarching hypothesis stated that repeated concussions would induce more …