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Full-Text Articles in Medicine and Health Sciences

Carprofen-Induced Oxidative Stress In Mitochondria Of The Colonic Mucosa Of The Dog, Lynne A. Snow Jan 2010

Carprofen-Induced Oxidative Stress In Mitochondria Of The Colonic Mucosa Of The Dog, Lynne A. Snow

LSU Master's Theses

Objectives 1) To measure conductance and permeability of canine colonic mucosa exposed to increasing concentrations of carprofen. 2) To compare conductance and permeability of canine colonic mucosa exposed to carprofen or 2,4-dinitrophenol (DNP) and tempol blockade. Design In vitro randomized block design Animal 20 mixed breed dogs Methods Conductance, mannitol flux, and histology were evaluated in colonic mucosa mounted in Ussing chambers. Mucosa was first exposed to increasing concentrations of carprofen. Mucosa was then exposed to either carprofen (200 μg/ml) or DNP (0.25mM) +/- tempol (1mM) pretreatment. Conductance over time, mannitol fluxes, and frequency of histologic categories were analyzed for …


Vocal Warm-Up Practices And Perceptions In Vocalists: A Pilot Survey, Allison Kimberly Gish Jan 2010

Vocal Warm-Up Practices And Perceptions In Vocalists: A Pilot Survey, Allison Kimberly Gish

LSU Master's Theses

Vocal warm-up exercises are believed to contribute to the prevention of vocal fold injury in professional voice users. Professional singers and students of singing consider a regular vocal warm-up regimen essential. There is conflicting information in the vocal pedagogy literature about the most effective and widely used vocal warm-up exercises and the optimal frequency and duration of vocal warm-up sessions. The goal of this current study was to investigate the characteristics of vocal warm-up regimens in the singing community using a survey. One hundred seventeen participants completed the survey. Participants included voice students from undergraduate, masters, and doctoral music programs …


Depolarization By Transient Receptor Potential Melastatin 4 In Pancreatic Alpha-Cells Regulates Glucagon Secretion, Piper Lynn Nelson Jan 2010

Depolarization By Transient Receptor Potential Melastatin 4 In Pancreatic Alpha-Cells Regulates Glucagon Secretion, Piper Lynn Nelson

LSU Master's Theses

The Transient Receptor Potential Melastatin 4 protein (TRPM4) is a member of the TRP family of ion channels that is expressed in both electrically excitable and non-excitable cells. Functional studies revealed that TRPM4 significantly impacts Ca2+ signals in both immune and pancreatic β-cells, which is important for cellular processes such as hormone secretion. However, its role in glucagon secreting α-cells has not been reported. Type 2 Diabetes Mellitus is often associated with increased glucagon levels; yet, the exact mechanism controlling its secretion is not known. In pancreatic α-cells, an increase in intracellular Ca2+ concentration causes glucagon secretion. We hypothesize that …


Treatment Effect Of Maximum Performance Speech Therapy For Individuals With Parkinson's Disease And Dysarthria, Heidi Huckabee Michiels Jan 2010

Treatment Effect Of Maximum Performance Speech Therapy For Individuals With Parkinson's Disease And Dysarthria, Heidi Huckabee Michiels

LSU Master's Theses

The Lee Silverman Voice Treatment (LSVT™) has received much attention in the past decade for its use in the treatment of individuals with Parkinson’s disease (Jones, 2005; Ramig, Countryman, O'Brien, Hoehn, & Thompson, 1996; Ramig, Sapir, Countryman et al., 2001; Wohlert, 2004). This intensive program requires therapy four times a week for four weeks in order to improve perceptual characteristics of the voice, such as loudness. However, since LSVT™ was introduced, the rehabilitation industry has experienced systematic reductions in allowable frequency and duration of covered services. The result has been that individuals often cannot qualify for the rigorous LSVT™ protocol …


Parent Report Of Home Literacy Experiences In Children With And Without Speech And Language Impairments, Amanda Blair Grace Jan 2010

Parent Report Of Home Literacy Experiences In Children With And Without Speech And Language Impairments, Amanda Blair Grace

LSU Master's Theses

The purpose of this study was to evaluate caregivers’ perceptions of their children’s literacy experiences and determine if their perceptions differed as a function of whether their children presented with speech and language impairment or with typical language development. Participants were caregivers of children, between the ages of 24 and 54 months. Eleven children presented with speech and language impairments (S/LI) and 14 children presented with typically developing (TD) language. Caregivers’ perceptions about early home literacy experiences were collected through a questionnaire. Results showed that there were no statistically significant differences between the two groups of caregivers’ responses to the …


Applicability And Integration Of Plasma Sprayed Hydroxyapatite Coated Ao Cortical Bone Screws In Equine Bone, Timm Gudehus Jan 2010

Applicability And Integration Of Plasma Sprayed Hydroxyapatite Coated Ao Cortical Bone Screws In Equine Bone, Timm Gudehus

LSU Master's Theses

To compare insertion temperatures and torques of Hydroxyapatite (HA) coated and uncoated 5.5 mm AO cortical screws in equine third metatarsal bones (MTIII) in vitro, and to compare insertion and extraction torques of HA coated and uncoated screws after 4, 8, 12 and 16 weeks of healing in equine third metacarpal bones (MCIII) in vivo. No significant temperature differences were recorded in cadaveric bones for AO and HA coated screws. Insertion torques were significantly higher for HA coated implants compared to uncoated screws. In vivo, the AO screws lost 50% of their initial stability within 4 weeks of healing and …