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Full-Text Articles in Medicine and Health Sciences
A New Experimental Approach To The Evaluation Of The Effect Of Narcotic Analgesics Upon Respiratory Function, Charles H. Pierce, Richard B. Mchugh, Raymond N. Bieter
A New Experimental Approach To The Evaluation Of The Effect Of Narcotic Analgesics Upon Respiratory Function, Charles H. Pierce, Richard B. Mchugh, Raymond N. Bieter
Journal of the Minnesota Academy of Science
Experimental models often used to study the effects of drugs upon respiratory function employ anesthetized animals. The present study eliminated the possible interference of anesthetics by using dogs altered only by a Permanent lracheostomy. Respiratory function was evaluated by determining end-expiratory (alveolar) CO, tension. The experimental design, an extension of the cross-over type, permitted the estimation of possible residual effects of the drugs applied in sequence la the same animals. Morphine Sulfate increasingly caused on elevation in alveolar pCO, while Meperidine HCl had no such effect. An antitussive meperidine derivative, WIN 13187, had respiratory effects similar to meperidine.
Accidental Poisoning In Young Children: Its Causes And Its Prevention, Charles H. Pierce, Harold N. Wright
Accidental Poisoning In Young Children: Its Causes And Its Prevention, Charles H. Pierce, Harold N. Wright
Journal of the Minnesota Academy of Science
Accidents, burns, drownings, and poisonings are the four most frequent causes of death among children. They far exceed the frequency of death from any of childhood's infectious diseases. With reasonable care, death from poisoning is probably the most amenable to prevention. Accidental poisoning, mainly in preschool children, is discussed from the standpoints of the major toxic hazards found around the usual home, their nature, incidence, location, and prevention.
The Abnormal Coxofemoral Articulation In The German Shepherd Dog, Griselda Hanlon
The Abnormal Coxofemoral Articulation In The German Shepherd Dog, Griselda Hanlon
Journal of the Minnesota Academy of Science
A common abnormality among dogs of the coxofemoral articulation, known as developmental hip dysplasia, is discussed with special reference to its occurrence in the German Shepherd breed. Some observations made from serial radiographic studies of the maturation of normal and abnormal coxofemorol articulation of 200 experimental German Shepherd dogs are presented, and a method of measuring the ilio-acetabular angle is described. Further evaluation will be made of the angle as an early predictor in the course of developmental hip dysplasia.