Medicine and Health Sciences Commons^™

Examining The Healthcare Journeys Of African American Individuals With Type 2 Diabetes Amid Covid-19, Lei Edmerson

Honors Theses

The overall purpose of this study is to explore the pandemic experience of African American’s with Type 2 Diabetes. This study was done to highlight a specific group of people who live with a chronic illness and the steps they took to ensure their safety during a pandemic. The COVID- 19 pandemic had been shown to adversely and disproportionately impact minorities and those with diabetes in regards to mortality rates. This study aims to bring light to the stories of those dealing with more than just the pandemic. It wanted to explore how they made it thus far, and if …

Ionic Liquid-Solvated Chitosan Nanoparticles As A Novel Method Of Treating Atopic Dermatitis, Leslie Bell

Honors Theses

Atopic dermatitis, or eczema, is an inflammatory skin disease resulting in dry, red, and itchy skin that affects almost 20% of the population of the Western world. This disease creates a physical, emotional, as well as financial burden on those affected, as well as their families. Current treatment options are only somewhat effective, and do not have a long duration of release and therefore efficiency. Furthermore, treatment plans involving corticosteroids need to be closely regulated to monitor side effects such as skin thinning. Other options include topical tacrolimus, emollients, and oral antihistamines, each with varied side effects. This project is …

Pragmatic Deficits In Attention-Deficit/Hyperactivity Disorder: Systematic Review And Meta-Analysis, Paige Kessler

Honors Theses

Background: Most studies have found pragmatic language skills to be poorer in attention-deficit/hyperactivity disorder (ADHD) populations, but there is no conclusive evidence.

Aim: Our aim was to conduct a meta-analysis of pragmatic language abilities in ADHD populations to more definitively demonstrate the extent of pragmatic language deficits in these populations as compared to typically developing (TD) populations.

Methods and procedures: Journal articles were identified using the search terms ((attention deficit) OR (adhd)) AND (pragmatics). Identified studies were screened and reviewed for inclusion criteria, descriptive information, and outcome variables. A meta-analysis was conducted, and individual effect sizes and overall effect size …

A Literature Review Of Mild Traumatic Brain Injury Research, Brindlea Peterson

Honors Theses

Mild traumatic brain injuries (mTBI) are a type of traumatic brain injury (TBI) usually sustained from an injury to the head and are hard to diagnose due to the lack of physical evidence seen in diagnostic radiology. The estimated worldwide rate of incidence each year is 42 million, making mTBIs rather common. In the US armed forces, that rate of incidence is even higher due to the dangerous nature of the work being done. Many complications can come from not properly addressing an mTBI after it happens which makes being able to determine an appropriate return-to-play or return-to-duty time very …

An Investigation Of Chronic Pain As A Much-Neglected Symptom Of Hypermobile Ehlers-Danlos Syndrome, Sydney Collins

Honors Theses

Ehlers Danlos Syndrome is a group of heritable loose connective tissue disorders with 13 distinguished subtypes. The hypermobile type of Ehlers Danlos Syndrome (hEDS) is the most common subtype and is caused by a genetic mutation that leads to defective collagen fibrils. This leads to joint instability and hypermobility, skin elasticity, widespread pain, fatigue, and generalized tissue fragility. Chronic pain is reported to be a symptom in as high as 92% of the hEDS population (Voermans et al., 2010); despite this prevalence, there is a significant lack of research, awareness, and treatment standardization regarding pain in hEDS. This literature review …

Healthcare Access Barriers And Proposed Solutions For Limited English-Proficient (Lep) Latinx Patients In Southwest Michigan, Carmen Vinkemulder

Honors Theses

This research study explores the circumstances and experiences of LatinX patients with limited English proficiency (LEP) when seeking treatment in the healthcare system of Southwest Michigan, in addition to proposing solutions to better facilitate this population’s access. The terminology used in this research, LatinX, is an American English neologism used as a genderinclusive term used interchangeably with Latino/a and/or Hispanic. This research provides an overview of the current socio-political legislature and climate of the American healthcare system as it pertains to the LatinX population to spread awareness and identify the barriers existing in our current healthcare model. This study will …

Barriers Of Bronson School Of Nursing Program, Karla Kline

Honors Theses

Aside from the rigorous coursework of nursing school, nursing students experience various barriers that impact their academic success. Barriers to successful completion of traditional Bachelor of Science of Nursing (BSN) programs include isolation, lack of peer connections, lack of faculty connections, lack of family support, lack of financial support, and mental health struggles (Shaw, 2015) (Seal & Woods, 2021). This research will aim at assessing and exploring these barriers students are facing, along with the additional or exacerbated barriers the COVID-19 pandemic has surfaced.

This study will expand on the research conducted by Shaw (2015), in which she examined the …

Potential Effects Of Animatronic Pet Ownership In College Students, Bayleigh Burling

Honors Theses

No abstract provided.

Test Transferability Of 3d-Mot Training On Soccer Specific Parameters, Micaela Dusseault

Honors Theses

Objective: The benefits of perceptual-cognitive training in elite level athletes has recently been investigated in multiple sports such as basketball, soccer, and archery, but conclusive evidence proving test transferability of 3D-MOT training is lacking. The purpose of this research is to examine the transferability of perceptual-cognitive training to on-field soccer performance parameters. Participants: NCAA Division I women’s soccer players (n=22) between the ages of 18-25 who were placed into either the experimental group (n=10) or control group (n=12). After baseline testing for both groups to determine visual tracking speed (VTS), the experimental group completed 10 3D-MOT training sessions with NeuroTracker …

Assessing The Impact Of Covid-19 Restrictions On The Perinatal Experience In Mississippi, Baylee Grimsley

Honors Theses

The purpose of this study is to assess how COVID-19 restrictions affected the perinatal experience of women in Mississippi. A flyer detailing the purpose and inclusion criteria of the study was sent via social media platforms. Five postpartum women from the Hattiesburg, Mississippi area participated in this study. Eight open-ended questions were asked in an interview format, and a seven-question demographic survey was given to each participant at the conclusion of the interview. Five restrictions related to COVID-19 were identified: visitor restrictions in the hospital, mask requirements in healthcare facilities, screening of patients upon admission to the Labor and Delivery …

Examining An Intersection Of Environmental Justice And Covid-19 Risk Assessment: A Review, Ashley Ellis

Honors Theses

This study views the risks associated with the novel coronavirus (COVID-19) as an environmental injustice issue due to the connection between existing environmental disparities and the disproportional negative impacts brought upon by the virus. The social and health determinants attributed to those environmental disparities have traditionally been evaluated as individual risk factors, an approach that fails to gauge the complexity of an environmental injustice issue. This study employs the emerging theory of intersectionality, a belief that phenomena cannot be linked to one principal cause but instead an interconnected web of influences, in order to synthesize the multitude of factors believed …

The State Of Healthcare Policy Education In Nursing School Curricula: A Literature Review, Katelyn Gebelein

Honors Theses

The purpose of this paper was to conduct a literature review regarding the current state of health policy education in nursing school curricula. Additionally, the paper will outline what improvements are being implemented in nursing education. The database CINAHL was used to conduct this study. According to the literature, there are an inadequate number of nurses participating in health policy reform which can be linked back to a lack of health policy education while in nursing school. The literature suggests options such as experiential learning, group activities and reflections, enhancing faculty knowledge, suggesting new teaching strategies, and implementing new courses …

Hiv-1 Transcription Elongation By Tat-Mediated Recruitment Of P-Tefb, Elizabeth Griggs

Honors Theses

Over 38.0 million people live with the human immunodeficiency virus (HIV) as of 462019. HIV hijacks the host's cellular machinery to replicate its viral DNA and transcribe the corresponding RNA. HIV-1 transcription relies on both cellular and viral transcription factors for proper regulation. The viral transcriptional activator Tat is a primary regulator. Transcription activation and elongation is controlled through the interaction of Tat with Positive Transcription Elongation Factor b (P-TEFb), a cellular transcriptional activator. The focus of this paper is 1) an in-depth understanding of the interaction between P-TEFb and Tat in HIV transcription, and 2) a review of recent …

Increased Incidence Of Substance Use And Substance Use Disorders Among Mexicans That Have Migrated To The United States, Emily Hock

Honors Theses

The United States is becoming increasingly older and more racially and ethnically diverse, with Mexican Americans adults aged 65 and over becoming the frontrunners in population growth. Substance use disorders are high among this particular population, with alcohol and tobacco being the most common culprits. Previous research suggests that the prevalence of drinking and smoking among Mexican Americans is increased compared to Mexicans living in Mexico, and substance use rates are highest in those most accustomed to United States culture. While acculturation may initially increase exposure to healthcare options, Mexican Americans are disproportionally uneducated and have lower socioeconomic status than …

Environmental Justice Analysis Of Drinking Water Policies In Michigan Cities, Annika Paldan

Honors Theses

This thesis examined environmental justice aspects of drinking water policies in four cities across Michigan: Flint, Birmingham, St. Joseph, and Benton Harbor. An overview of the history of the environmental justice movement, environmental racism, and drinking water policies provided the basis for a four-part evaluative criterion to assess environmental justice components at the municipal level. These criteria include (1) housing tenure, (2) age, size, and service line composition of the infrastructure, (3) public participation in the policy process, and (4) emergency management of the city. Findings indicate that environmental justice has come a long way, with cities now incorporating components …

Literature Review Of Human Hdr Syndrome With Gata3 Haplo Insufficiency, Olivia Ambursley-Gries

Honors Theses

This literature mining project is regarding mutations that cause hearing loss in patients with human hypo parathyroid, deafness, and renal dysplasia (HDR) syndrome caused by a mutation in the GATA3 gene. The disease is unique; not all diagnosed individuals present with all symptoms of the triad. Van Esh et al. found that the haploinsufficiency of the GATA3 is found on chromosome 10p14-p15 (ref.1). The focus of this work is to condense the literature on GATA3 haploinsufficiency correlating to human HDR syndrome. Due to the lack of global healthcare access, it can be assumed that many cases remain undiagnosed; 180 have …

Female Infertility In The United States And India: An Analysis Of Treatment Barriers And Coping Strategies, Devneet Singh

Honors Theses

This research studies barriers to accessing fertility treatment in the United States (U.S.) and India, as well as the coping strategies infertile women use. Barriers include reproductive health knowledge, cost, and politics, while coping is affected by cultural stigma, family, and religion. These two countries were chosen for their different cultural contexts, healthcare systems, and political infrastructure. Ten fertility specialists across both countries were interviewed as expert informants. Reproductive health knowledge was the most important barrier to accessing care in both countries, with similar gaps in understanding when and what type of care to utilize, though social media can educate …

Developing Prediction Models For Kidney Stone Disease, Joseph Palko

Honors Theses

Kidney stone disease has become more prevalent through the years, leading to high treatment cost and associated health risks. In this study, we explore a large medical database and machine learning methods to extract features and construct models for diagnosing kidney stone disease.

Data of 46,250 patients and 58,976 hospital admissions were extracted and analyzed, including patients’ demographic information, diagnoses, vital signs, and laboratory measurements of the blood and urine. We compared the kidney stone (KDS) patients to patients with abdominal and back pain (ABP), patients diagnosed with nephritis, nephrosis, renal sclerosis, chronic kidney disease, or acute and unspecified renal …

A Case For Early Intervention Speech Therapy For All Children In The Foster Care System, Moriah Manchack

Honors Theses

A look into the need for Early Intervention speech therapy services for children in the foster care system, as well as the laws and provisions for these services.

Acute Physiological And Perceptual Responses To Unilateral Versus Bilateral Walking With Blood Flow Restriction, Sage Donaldson

Honors Theses

The use of blood flow restriction (BFR) has skyrocketed in popularity in the past few years as a therapeutic modality. Studies have shown that the application of BFR at 20-30% of maximal oxygen consumption (VO_2max) yields similar improvements in cardiovascular fitness, muscle mass, and strength when compared with traditional exercise at 60-90% of VO_2max. The substantially lower workload accompanying BFR allows for more tolerable workloads in special populations, such as those recovering from musculoskeletal injury. Because previous studies regarding BFR have mainly focused on bilateral BFR, it is unclear how unilateral BFR compares to bilateral BFR. …

Effect Of Aerobic Exercise With Blood Flow Restriction On Substrate Utilization And Energy Expenditure, Nathen Andrews

Honors Theses

The purpose of this study was to examine the effects of intermittent blood flow restriction (BFR) compared to low- (LIIE) and high-intensity interval exercise (HIIE) on energy expenditure (EE) and substrate utilization. Participants randomly performed each interval exercise protocol, and then rested for a three-hour period, in which EE and substrate utilization were measured. Total EE was different between BFR (321.6 ± 30.1 kcals), HIIE (254.5 ± 33.5 kcals), and LIIE (287.1 ± 25.5 kcals). Fat oxidation (FatOx) in BFR (1hr = 0.14 ± 0.01 g / min, 3hr = 0.11 ± 0.01 g / min) was greater than LIIE …

The Effect Of Advocate Disclosure On The Perceptions Of A Young Adult Who Stutters, Madeline Simpson

Honors Theses

This between-group study designed weighed the effects of stuttering disclosure on the perceptions of a 17-year-old male who stutters, relative to perceived speech skills and personality characteristics. 1225 participants were included in the dataset analysis with a balanced distribution across all ranges. The conditions used in this study include (1) control condition (no disclosure), as well as experimental conditions including: (2) father disclosure, (3) male coach disclosure, (4) female teacher disclosure, (5) girlfriend disclosure, and (6) female speech-language pathologist. Participants in the control group only viewed the primary video stimulus, while participants in the experimental groups viewed one of the …

Light And Heavy Verb Usage By People With Non-Fluent Aphasia, Chase Sophia Kozak

Honors Theses

The purpose of the study was to investigate the discourse elicitation task effect and whether it affects the production of verbs with different semantic weight (light verbs with vague semantic representations, e.g., ‘do’, or heavy verbs with specific semantic representations, e.g., ‘deliver’). Thirty people with non-fluent aphasia and twenty people without aphasia were included. The light and heavy verb ratios over the total number of verbs were calculated for two discourse elicitation tasks: sequential picture description and storytelling. The results for the healthy control group showed that they produced a significant higher heavy verb ratio in sequential picture description than …

The Rates Of Caries Prevalence By Sex And Age From Individuals In St. Mary Graces And East Smithfield Cemeteries, Elizabeth Houston, Joseph Upton

Honors Theses

Caries are a common pathology in past and current populations, and because of the close interaction of dentition with diet, archaeologists are able to infer components of a population’s culture from pathology like caries (Lanfranco & Eggers, 2010). Most literature implies that women have higher rates of caries than men because of cultural practices and natural physiological differences which are thought to put women at an increased risk (Lukacs, 2008). Another established trend throughout literature is that caries prevalence tends to increase with age, regardless of sex (Hillson, 2008). We evaluated data from the East Smithfield (1348-1350 AD) and Saint …

Clinical Effectiveness Of Early Intervention Via A Hybrid Teletherapy Model: Children With Autism Spectrum Disorder, Rylan Ponthier

Honors Theses

Purpose: The purpose of the present study was to evaluate the efficacy of Early Intervention (EI) provided via a hybrid model of teletherapy and traditional face-to-face therapy for children with Autism Spectrum Disorder (ASD) compared to children without ASD.

Methods: In total, 10 children were evaluated receiving early intervention via a hybrid model of teletherapy and traditional face-to-face therapy. The children were divided up into two groups. Group 1 consisted of 5 children with ASD and Group 2 consisted of children without ASD. All children were assessed using the Rossetti Infant-Toddler Language Scale (RITLS).

Results: After 20 early intervention sessions, …

Chronic Exercise And Memory Interference, Lisa Vogelgesang

Honors Theses

This online study examined whether chronic exercise is associated with attenuated memory interference. Sixty-three healthy, young adults completed an interference task (AB/AC-paradigm) and self-reported the number of days and minutes a day they engaged in moderate-to-vigorous physical activity. We found that proactive interference (PI), but not retroactive interference (RI), occurred but none of the exercise modalities significantly impacted PI. Future studies should evaluate whether different interference tasks display diverse sensitivities to exercise-induced changes in memory interference. Moreover, other potential modulating factors, such as the duration and intensity of the exercise should be controlled for.

Analysis Of Multigenerational Behavioral Effects Of Dietary Benzo[A]Pyrene Exposure In Adult Zebrafish, Mary Beth Gillespie

Honors Theses

Benzo[a]pyrene (BaP) is a polycyclic aromatic hydrocarbon that is linked to negative reproductive and developmental effects in humans and animals. Because BaP is carcinogenic, and its continued presence in the environment allows it to be inhaled and ingested, better understanding of the effects of BaP is needed. To determine the behavioral effects of BaP exposure, zebrafish were used as a model. Wild-type zebrafish (5D) underwent two separate 21-day dietary exposures to 2.5 and 25 μg BaP/g fish to compare how BaP exposure affects locomotor activity. Following the dietary exposure, fish were mated to obtain and raise the F1 generation to …

Simian Varicella Virus Antibody Response In Recombinant Svv-Siv Immunized Primates, Kiser Horne

Honors Theses

Since its emergence in the early 1980’s HIV has killed approximately 32 million people, and continues to kill over half a million people every year. Significant research into potential vaccines and cures for HIV has been ongoing for decades but has been largely unsuccessful. One of the more promising technologies that is being investigated to develop an HIV vaccine is recombinant vaccine technology. The study presented in this thesis aims to use simian varicella virus (SVV) and simian immunodeficiency virus (SIV) to act as a model for recombinant vaccine development. If a recombinant SVV-SIV vaccine can be proven safe and …

Impact Of Covid-19 On Physical Activity And Health Influences Among College Students, Rachael Larkin

Honors Theses

Objective: To assess the associations between physical activity, subjective well-being (SWB), and social media influences before, during, and after the 2020 COVID-19 period among college-aged students. Participants: Male and female students from the University of Mississippi who were between the ages of 18-25 volunteered to participate in this study. Out of 10,000 invitation emails distributed, a total of 290 individuals responded and were used for the subsequent analysis. Results: Almost half of the respondents (46.1%) noted a decrease in physical activity from before March-May (M-M) 2020 to during M-M 2020. In addition, 41% of the respondents reported an increase in …

Coronary Artery Disease: An Analysis Of Its Biochemical, Physiological, And Sociological Causes And Effects, Alexander Velazquez

Honors Theses

Coronary Artery Disease (CAD) is a serious condition caused by a buildup of plaque in your coronary arteries, the blood vessels that bring oxygen-rich blood to your heart. It disproportionately affects millions of Americans and thousands of Mississippians. This study presents the results of an evaluation of causation factors of CAD, the physiological impact on the body, and the contributing determinants of CAD on Mississippi populations. Data on Mississippi populations were collected using the Center for Population Studies at the University of Mississippi. A multitude of individuals were evaluated when examining the causes and effects of CAD including men, women, …