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Honors Theses

2008

Neuroprotection

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Resveratrol Modulation Of Microglial Activation And Provision For Neuroprotection In Multiple Sclerosis, Joseph L. Green Jan 2008

Resveratrol Modulation Of Microglial Activation And Provision For Neuroprotection In Multiple Sclerosis, Joseph L. Green

Honors Theses

Multiple sclerosis (MS) is an autoimmune disease affecting over 2.5 million people worldwide. In MS, myelin sheaths surrounding the axons of neurons are attacked by the immune system, leading to many deleterious symptoms. No cure for MS has been found, but some treatments reducing the number of exacerbations are available. Studies on resveratrol show the compound to have anti-inflammatory properties that could be beneficial in the treatment of diseases like MS. In our research, we used a cellular model to imitate neurons of the central nervous system and tested the effects of resveratrol in the hope of finding neuroprotective properties.