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Treating Breast Cancer With Light: The Creation Of Two Photodynamic Therapy Agents, Victoria Lackey May 2018

Treating Breast Cancer With Light: The Creation Of Two Photodynamic Therapy Agents, Victoria Lackey

Honors Theses

Photodynamic therapy (PDT) is a treatment for a wide display of diseases, including cancer, that has become gradually widespread. The procedure requires the usage of photosynthesizing agents, which are activated in the presence of light. One quite successful photodynamic therapy agent is an aromatic structure made up of four pyrrole rings called a porphyrin. This research focused on producing the water-soluble porphyrins, H2TPP-3-PEG-OH and H2TPP-PiperMe-OH, through the attachment of the starting porphyrin, H2TPPC, with 3-polyethyleneglycol and 3-piperidinemethanol, respectively. The novel, water-soluble agent was purified and characterized by infrared spectroscopy (IR), nuclear magnetic resonance spectroscopy (NMR), and UV-vis spectroscopy. Purity was …


An Assessment Of The Effects Of Medical Marijuana On The Quality Of Patient Life, Kori L. Bullard Jan 2018

An Assessment Of The Effects Of Medical Marijuana On The Quality Of Patient Life, Kori L. Bullard

Honors Theses

America is known as the land of opportunity. People attempting to better their lives tend to see America as an opportunity to do so. This statement remains true for the American medical field. Americans are known as advanced in treatment options for various diseases. With this being said, there are few diseases that still bring forth complete fear in the minds of the people of America. In spite of this, "You have been diagnosed with cancer" is a statement that generates this fear. Cancer is one of the leading causes of death worldwide. Current treatments for cancer are invasive, expensive, …