Medicine and Health Sciences Commons^™

Pfas Environmental Contamination In Central Maine, Megan H. Andersen

Honors Theses

PFAS (per- and polyfluoroalkyl substances) are toxic, persistent, and bioaccumulative chemicals that are used in a variety of consumer products and industrial applications. Paper mills across the state of Maine have used PFAS in their industrial paper making processes, and their wastes often flow for treatment into municipal sewage treatment facilities. PFAS contaminated municipal wastewater from the general use of PFAS consumer products are also processed by these plants. Liquid waste is condensed into solid waste septage and sludge, and in what was thought to be an environmentally friendly repurposing practice, municipal sludge and septage has been spread on plots …

"It’S Just Another Thing”: Perceptions Of Well Water Quality And Barriers In An Arsenic Hot Spot, Linzy Rosen

Honors Theses

Privately owned water is the primary source of drinking water for 43 million Americans. Although residential or private wells are susceptible to a variety of contaminants, the Safe Drinking Water Act of 1974 positions individuals as responsible for the testing, remediation, and management of this water. Despite the elevated presence of arsenic in Maine, which is linked to various cancers, cardiovascular disease, and neurological damage, little is known about how private well owners perceive the safety and quality of their own water.

This study takes a qualitative approach to understanding concerns and opinions by conducting semi - structured interviews with …

Science And Sadness: Critiques On How We Handle Alzheimer’S Disease And Dementia, Katherine Martinez

Honors Theses

In our society, an individual’s worth is tied to the state of their cognitive function which affects the discourse about neurodegenerative illnesses, causing it to mostly fall under two branches: “The Dread” and “Science as the Holy Grail”. “The Dread” addresses how Alzheimer’s Disease (AD) and other dementias are typically perceived as devastating illnesses to be feared. “Science as the Holy Grail” represents the hope and faith that is invested into potential technoscientific developments without the guarantee of any consequential results. Limiting the narrative to these two categories negatively impacts the quality of life (QOL) of AD patients, caregivers, and …

The Multifront Battle Waged Against Female Autonomy: A Comparative Study Of Ancient Medical And Literary Texts, Leah K. Montello

Honors Theses

Male authors have long waged a multifront campaign against female independence. In this thesis, I focus on two specific fronts: literary and medical texts of the Classical Greek period. This thesis intends to explore the varying strategies in a selection of works, employed to reinforce prescribed gender norms. I approach this with a feminist lens to critique attempts made by elite educated Greek men to define what a woman ought to be like. I do not, however, explore every single tactic a medical and literary writer has applied to uphold patriarchal norms. My two body chapters revolve respectively around two …

The New Mainers: An Exploratory Analysis Of Healthcare Experiences In The Somali Bantu Community, Jordan R. Mcclintock

Honors Theses

Healthcare inequities within the United States’ Western model of medicine have existed for hundreds of years. The purpose of this year-long project was to analyze the existing qualitative and quantitative studies of healthcare barriers for the Southern Maine Somali Bantu population, as well as compiling narrative pieces from Maine non-governmental organizations that provide community resources. In doing so, the idea of healthcare access and literacy was analyzed through means of understanding systemic barriers. Overall, the findings of this exploratory project point to a lack of cultural humility within medicine, the importance of recognizing intersectional identities in quality of healthcare, and …

The Role Of Socioeconomic Status In Cognition And Brain Health Across The Lifespan, Erica Chung

Honors Theses

Disparities in cognition are inevitable throughout the lifespan due to socioeconomic gaps. Individuals of lower socioeconomic status (SES) may have fewer access to environmental resources, especially with regard to education, than individuals of higher socioeconomic status. Differences in available resources from a young age may affect brain development, leading to detriments in cognition and behavior, further impacting socioeconomic success in adulthood. In the present study, we modeled the development of the dorsolateral prefrontal cortex (DLPFC) and changes in cognitive function throughout the life trajectory in the Nathan Kline Institute for Psychiatric Research Rockland Sample. The DLPFC volume was predicted to …

Understanding The Role Of Race In American Medicine, Fariel C. A. Lamountain

Honors Theses

Long running inequity in health care and outcomes in the United States stem from failure to acknowledge the underlying role of the Transatlantic slave trade as it manifests in all facets of American society and commerce. This paper focuses specifically on the American medical system and its foundations to understand the precursors to generational trends in lack of access to healthcare and poor health for Black communities. This paper uses a three-pronged approach to understand the racist cycle of inequity, highlighting the history and origins of racism in American medicine, personal accounts and statistical evidence of inequity, and community and …

Characterizing Cellular Stress, Hippocampal Function, And Behavior In A Novel Rat Model Of Alzheimer's Disease, Anne A. Schulman

Honors Theses

Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder that affects over 5 million individuals in the United States alone. While AD is primarily thought of as a disease that destroys neural networks required for memory recall and formation, AD also cause impairment in emotional regulation, cognitive flexibility, and executive function pathways. The cause of AD is unknown; however, the allele ApoE4 has been identified as a risk factor for the onset of AD. ApoE4 provides a valuable opportunity to study AD through animal models. This thesis utilized a human ApoE4 transgenic rat model (hApoE4) to investigate the biological and behavioral …