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Aptamer-Based Spr Biosensor For Detection Of Avian Influenza Virus, Hua Bai
Aptamer-Based Spr Biosensor For Detection Of Avian Influenza Virus, Hua Bai
Graduate Theses and Dissertations
Rapid and specific detection of avian influenza (AI) virus is urgently needed with the concerns over the outbreaks of highly pathogenic H5N1 avian influenza in animal and human infection. Aptamers are artificial oligonucleic acid that can specifically bind to target molecules. They show comparable affinity for target virus and better thermal stability than monoclonal antibodies. Those advantages make aptamers promising candidates in diagnostic and detection applications. The goal of this research was to use DNA&ndashaptamer as the specific recognition element in a portable surface plasmon resonance (SPR) biosensor for detection of AI H5N1 virus in poultry.
A SPR biosensor was …