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Full-Text Articles in Medicine and Health Sciences

Effects Of The Selective Gsk3b Inhibitor, Tideglusib, On Ethanol Consumption, Anxiety-Like Behavior, Taste Preference, And Downstream Proteins, Sam Gottlieb, Douglas Bledsoe, Jessica L. Maltman, Alanna Morgan, Jennifer T. Wolstenholme, Michael F. Miles Jan 2022

Effects Of The Selective Gsk3b Inhibitor, Tideglusib, On Ethanol Consumption, Anxiety-Like Behavior, Taste Preference, And Downstream Proteins, Sam Gottlieb, Douglas Bledsoe, Jessica L. Maltman, Alanna Morgan, Jennifer T. Wolstenholme, Michael F. Miles

Graduate Research Posters

Background: We have shown modulations in glycogen synthase kinase 3 beta (GSK3B) abundance or activity regulate ethanol consumption, suggesting potential as a therapeutic target for alcohol use disorder (AUD). Here we report the GSK3B inhibitor tideglusib’s actions on ethanol consumption, basal behaviors, and modulation of GSK3B targets.

Methods: C57BL/6J males and females received i.g. 200mg/kg tideglusib, except drinking-in-the-dark (males;100mg/kg i.p.). Drinking-in-the-dark (DID): Mice given 20% ethanol 4-hours, 4-days/week x 3 weeks and then i.p. tideglusib or vehicle x 4 days in a Latin Square design with ethanol consumption measured daily. Light/Dark Box: Mice gavaged with tideglusib or vehicle …


A Marginal Identity Model For Those In The "In-Between", Francine S. Singson, Sonia Meyer, Christine A. Reid Jan 2022

A Marginal Identity Model For Those In The "In-Between", Francine S. Singson, Sonia Meyer, Christine A. Reid

Graduate Research Posters

  1. Background

In existing models exploring the formation cultural identity, there is emphasis on development from the perspective of race or country of origin. While these models have made significant contributions to the study of identity development in the fields of counseling and psychology, research on the identity development of people who exist within the spectrum between traditionally acknowledged identities (Deaf/Hearing, LGBTQIA+, first/second generation) is lacking.

  1. Methods

To explore the merit of establishing a distinct theory exploring development of individuals whose identities exist between the existing binaries of identity, a systematic review and analysis of current literature was performed. Subsequently, a …