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Patent: Nestorone®/Estradiol Transdermal Gel, Régine Sitruk-Ware, Dario Norberto Ramon Carrara, Arnaud Grenier
Patent: Nestorone®/Estradiol Transdermal Gel, Régine Sitruk-Ware, Dario Norberto Ramon Carrara, Arnaud Grenier
Formulation/Product Development
The invention discloses compositions and methods for ensuring in both women of fertile age where it ensures also a contraception with additional health benefits and in postmenopausal women where it offers a hormonal therapy with additional medical benefits such as the potential for lower risk of thrombosis. The compositions comprising NES as a potent progestational and antiovulatory agent with no androgenic nor estrogenic nor glucocorticoid effect, and combined with estradiol formulated for non-oral transdermal administration as specific daily doses.