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Full-Text Articles in Medicine and Health Sciences
Pre-Existing Diabetes Mellitus, Hypertension And Kidneydisease As Risk Factors Of Pre-Eclampsia: A Disease Of Theories And Its Association With Genetic Polymorphism, Abdullah Salah Alanazi, Francis Victor, Kanwal Rehman, Yusra Habib Khan, Ismaeel Yunusa Ph.D., Abdulaziz Alzarea, Muhammad Sajid Hamid Akash, Tauqeer Hussain Mallhi
Pre-Existing Diabetes Mellitus, Hypertension And Kidneydisease As Risk Factors Of Pre-Eclampsia: A Disease Of Theories And Its Association With Genetic Polymorphism, Abdullah Salah Alanazi, Francis Victor, Kanwal Rehman, Yusra Habib Khan, Ismaeel Yunusa Ph.D., Abdulaziz Alzarea, Muhammad Sajid Hamid Akash, Tauqeer Hussain Mallhi
Faculty Publications
Pre-existing diabetes, hypertension and kidney disorders are prominent risk factors of pre-eclampsia (PE). It is a multifactorial pregnancy disorder associated with high blood pressure, proteinuria, and multiorgan failure, which develops after the 20th week of pregnancy. It is one of the most feared pregnancy disorders, as it consumes thousands of fetomaternal lives per annum. According to clinical and pathological studies, the placenta appears to be a key player in the pathogenesis of PE; however, the exact origin of this disorder is still under debate. Defective placentation and angiogenesis are the hallmarks of PE progression. This angiogenic imbalance, together with maternal …
Quantile Differences In The Age-Related Decline In Cardiorespiratory Fitness Between Sexes In Adults Without Type 2 Diabetes Mellitus In The United States, Andrew Ortaglia, Melissa Stansbury, Michael David Wirth, Xuemei Sui, Matteo Bottai
Quantile Differences In The Age-Related Decline In Cardiorespiratory Fitness Between Sexes In Adults Without Type 2 Diabetes Mellitus In The United States, Andrew Ortaglia, Melissa Stansbury, Michael David Wirth, Xuemei Sui, Matteo Bottai
Faculty Publications
Objective: To comprehensively assess the extent to which the decline in cardiorespiratory fitness (CRF) with age differs between sexes. Participants and Methods: This study used data from the Aerobics Center Longitudinal Study, conducted between September 1974 and August 2006, consisting primarily of White adults from middle-to-upper socioeconomic strata restricted to adults without type 2 diabetes mellitus (33,742 men and 9,415 women). Quantile regression models were used to estimate the differences in age-associated changes in CRF between the sexes, estimated using a maximal treadmill test. Results: For adults aged up to 45 years, significant differences in slopes relating to age and …