Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Applications Of Ct Perfusion-Based Triaging And Prognostication In Acute Ischemic Stroke, Eric A. Wright
Applications Of Ct Perfusion-Based Triaging And Prognostication In Acute Ischemic Stroke, Eric A. Wright
Electronic Thesis and Dissertation Repository
CT Perfusion (CTP) is a minimally invasive imaging technique that aids acute ischemic stroke (AIS) triage and prognostication by determining tissue viability based on hemodynamic parameters. The goals of this research are to determine: 1) CTP thresholds for estimation of infarct and penumbra volume, 2) how CTP scan duration impacts infarct and penumbra volume estimates, and 3) reliability of CTP for predicting functional outcomes following intra-arterial therapy (IAT).
Chapter 2 introduced an experimental study for determining ischemia-time dependent thresholds for brain infarction using multimodal imaging in a porcine stroke model that is easier to implement than previous large animal stroke …
High Performance Optical Computed Tomography For Accurate Three-Dimensional Radiation Dosimetry, Kurtis Hendrik Dekker
High Performance Optical Computed Tomography For Accurate Three-Dimensional Radiation Dosimetry, Kurtis Hendrik Dekker
Electronic Thesis and Dissertation Repository
Optical computed tomography (CT) imaging of radiochromic gel dosimeters is a method for truly three-dimensional radiation dosimetry. Although optical CT dosimetry is not widely used currently due to previous concerns with speed and accuracy, the complexity of modern radiotherapy is increasing the need for a true 3D dosimeter. This thesis reports technical improvements that bring the performance of optical CT to a clinically useful level. New scanner designs and improved scanning and reconstruction techniques are described.
First, we designed and implemented a new light source for a cone-beam optical CT system which reduced the scatter to primary contribution in CT …