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Full-Text Articles in Medicine and Health Sciences
Optimization Of A Boundary Element Approach To Electromagnet Design With Application To A Host Of Current Problems In Magnetic Resonance Imaging, Chad T. Harris
Optimization Of A Boundary Element Approach To Electromagnet Design With Application To A Host Of Current Problems In Magnetic Resonance Imaging, Chad T. Harris
Electronic Thesis and Dissertation Repository
Magnetic resonance imaging (MRI) has proven to be a valuable methodological approach in both basic research and clinical practice. However, significant hardware advances are still needed in order to further improve and extend the applications of the technique. The present dissertation predominantly addresses gradient and shim coil design (sub-systems of the MR system).
A design study to investigate gradient performance over a set of surface geometries ranging in curvature from planar to a full cylinder using the boundary element (BE) method is presented. The results of this study serve as a guide for future planar and pseudo-planar gradient systems for …
Imaging Breast Cancer Progression And Lymph Node Metastases In Murine Models Using Mri And Magnetic Nanoparticles, Vasiliki Economopoulos
Imaging Breast Cancer Progression And Lymph Node Metastases In Murine Models Using Mri And Magnetic Nanoparticles, Vasiliki Economopoulos
Electronic Thesis and Dissertation Repository
Most breast cancer related deaths are caused by the spread or metastasis of the primary tumor to distant sites in the body. The lymph nodes are one of the first places where metastases can be detected and are frequently examined for macroscopic metastases to help determine course of treatment for patients. However, little is known about the significance of microscopic metastases and disseminated individual cancer cells within the nodes. The goal of this work was to use MRI to monitor the development of primary tumors and lymphatic metastases in models of breast cancer.
In this thesis, we examined the MRI …
Delta Relaxation Enhanced Magnetic Resonance - Development And Application Of A Field-Cycling Contrast Mechanism, Yonathan Araya
Delta Relaxation Enhanced Magnetic Resonance - Development And Application Of A Field-Cycling Contrast Mechanism, Yonathan Araya
Electronic Thesis and Dissertation Repository
Delta relaxation enhanced magnetic resonance (dreMR) is a novel imaging method capable of producing contrast proportional only to the concentration of the bound form of the targetable contrast agent using a dynamic field-cycling technique. The characteristic high relaxivity magnetic field dependence of bound paramagnetic contrast agents enables suppression of tissue contrast from unbound agents and unenhanced tissue, thereby increasing probe specificity. The dreMR technique requires an auxiliary actively shielded field-shifting insert electromagnet to modulate the strength of the main clinical magnetic field as a function of time during the relaxation and evolution periods of a pulse sequence.
Ablavar (approved for …