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Electronic Thesis and Dissertation Repository

2011

Osteoarthritis

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Full-Text Articles in Medicine and Health Sciences

Prehabilitation For Total Knee Arthroplasty: A Patient-Centred Approach To Maximizing Surgical Outcomes, Carly D. Mckay Jul 2011

Prehabilitation For Total Knee Arthroplasty: A Patient-Centred Approach To Maximizing Surgical Outcomes, Carly D. Mckay

Electronic Thesis and Dissertation Repository

The purpose of this dissertation was to investigate the role of prehabilitation in post-operative recovery for patients undergoing total knee arthroplasty (TKA) for osteoarthritis. Study one was a meta-analysis that aimed to consolidate the body of knowledge regarding prehabilitation for TKA patients. Study two compared the Lower Limb Tasks Questionnaire (LLTQ) to the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) in terms of agreement and responsiveness. Study three investigated the effect of a six-week pre-surgical strength training program on post-operative outcomes (quadriceps strength, mobility, pain, self-reported function, health-related quality of life, arthritis self efficacy) for TKA patients. Finally, study …


Investigation Of Subchondral Bone Abnormalities Associated With Osteoarthritis Using Image-Based Biomechanics, David D. Mcerlain Jun 2011

Investigation Of Subchondral Bone Abnormalities Associated With Osteoarthritis Using Image-Based Biomechanics, David D. Mcerlain

Electronic Thesis and Dissertation Repository

Osteoarthritis (OA) is degenerative disease caused by a mechanical failure of bone and cartilage. Common risk factors for developing OA include: being over-weight, female, having joint malalignment, or a history of prior joint injury. Post-traumatic OA is extremely common in the knee as individuals frequently suffer injuries to structures that provide stability to the joint. To enhance our understanding about OA, animal models are employed where the injury can be and monitored in a controlled environment. When used in conjunction with pre-clinical imaging techniques the longitudinal degradation of bone and cartilage can be quantitatively monitored in vivo. Recent evidence …