Medicine and Health Sciences Commons^™

Porphyromonas Gingivalis, Ethanol, And Chronic Diseases., Nicholas Alan Short

Electronic Theses and Dissertations

This dissertation is an investigation into the relationships among Porphyromonas gingivalis, ethanol, and a series of chronic diseases, focusing primarily on atherosclerosis. It uses evolutionary theory to understand clinical parameters related to chronic disease biology. The initial research question was, "If people who drink a glass of wine each day have a lower risk for atherosclerosis, could one explanation involve antibacterial effects on pathogens associated with causing atherosclerosis, namely, Porphyromonas gingivalis?". This dissertation is divided into four chapters. Chapter One provides the foundational information pertinent to the dissertation. Chapter Two describes an in- vitro experiment aimed at understanding …

Histone Deacetylases In Alcohol Associated Liver Disease., Srineil Bodduluri

Electronic Theses and Dissertations

Alcohol abuse is endemic worldwide and there is no FDA approved treatment for Alcohol-Associated Liver Disease (ALD). Many scholars have posited that targeting Histone Deacetylases (HDAC) may be therapeutic in ALD intervention. In this study, the changes in hepatic gene expression and immune phenotyping of mice undergoing chronic plus binge alcohol exposure was examined. The characterization of relative mRNA levels for all 18 HDAC were performed. Results showed decreased expression of the genes HDAC 1,7,9,10,11 and Sirtuin enzymes (SIRT) 3,4,5,7. Other pathways related to lipid metabolism as well as systemic inflammation and hepatic injury also exhibited significant changes. These altered …

Investigating The Association Between Adolescent Polysubstance Use, Crime, And Violence In The United States, Christian Nwabueze

Electronic Theses and Dissertations

The lifetime prevalence of alcohol in the United States is 8% and lifetime prevalence of illicit drug use is about 2-3%. Substance use is common among adolescents and polysubstance use is becoming a public health threat.

The prevalence of adolescent physical dating violence was 8.2%, the prevalence of adolescent sexual violence was also 8.2% while the prevalence of dual adolescent physical and sexual violence was 2.6%. Compared to those who used only single substances, adolescents who did not use any substance were 60% less likely (OR = 0.42, 95% CI = 0.24 – 0.74) to experience physical dating violence, 50% …

Std Prevention: An Educational Intervention For Exotic Dancers, Maria Delurdes Dehoyos

Electronic Theses and Dissertations

The Centers for Disease Control and prevention reported nearly 2.3 million STD cases diagnosed in 2017, and the number is continuing to rise. San Antonio, Texas, is ranked third in the state of Texas with the highest STD rates and leading in the state with congenital syphilis. There is an increased risk for contracting STDs working in the sex industry. There are little to no studies pertaining to any educational interventions offered to exotic dancers to increase personal knowledge on STDs. This research has focused on an educational intervention offered by a nurse practitioner to exotic dancers in two adults-only …

A Process Evaluation Of The Brief Alcohol Screening Intervention For College Students Program At The University Of Mississippi, Tiffany Bouldin Lawson

Electronic Theses and Dissertations

Alcohol misuse by students is a prevalent public health problem on college campuses across the nation. Underage drinking and binge drinking are two distinct forms of alcohol misuse that are comamong college students and often result in negative consequences for the students, the universities, and the surrounding communities. As a result, there is an increasing need for universities to provide targeted intervention programs for students who misuse alcohol. Furthermore, it is important that the selected interventions are capable of successful implementation on campus. The University of Mississippi currently utilizes the brief alcohol screening intervention for college students (basics) program for …

The Relationship Between Tobacco, Alcohol, And Marijuana Use Among Teenagers., John Donald Rose

Electronic Theses and Dissertations

The purpose of this study was to explore the relationship between alcohol, tobacco, and marijuana use among teenagers. This study examined three research questions: (1) Is there a relationship between demographic characteristics (i.e., sex and race), the attitudinal variable (attachment to family), and the admitted use of marijuana, alcohol, and tobacco among teenagers? (2) Is there a relationship between the use of marijuana by teenagers and the use of tobacco by teenagers? (3) Is there a relationship between the use of marijuana by teenagers and the use of alcohol by teenagers?

The data used for this paper were from the …

Reasons For Living And Suicidal Ideation Among College Students With Varying Levels Of Risk For Alcohol Related Problems., Dorian A. Lamis

Electronic Theses and Dissertations

Every year in the United States approximately 30,000 people commit suicide including approximately 1,100 college students. Furthermore, heavy alcohol consumption is prevalent on many college campuses and has been linked to suicidal behavior. The present study was conducted to examine suicidal ideation and reasons for living in college students with varying levels of risk for alcohol related problems. Undergraduate students (n = 161) were administered a survey to assess demographics, suicide ideation status, reasons for living, and the participant's level of risk for alcohol related problems. Results indicated that suicide ideators are significantly more likely than non-ideators to be at …