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Full-Text Articles in Medicine and Health Sciences
The Effect Of Nitrate Supplementation On Exercise Tolerance And Performance: A Systematic Review And Meta-Analysis, Gavin Van De Walle
The Effect Of Nitrate Supplementation On Exercise Tolerance And Performance: A Systematic Review And Meta-Analysis, Gavin Van De Walle
Electronic Theses and Dissertations
The purpose of this paper was to systematically review the current literature and evaluate the overall efficacy of nitrate supplementation on exercise tolerance and performance by meta-analysis. Studies were eligible for inclusion if they met the following criteria: 1) were an experimental trial published in an English peer-reviewed journal; 2) compared the effects of inorganic nitrate consumption with a non-bioactive supplement control or placebo; 3) used a quantifiable measure of exercise performance; and 4) was carried out in apparently healthy participants without disease. A total of 29 studies were identified that investigated the effects of nitrate supplementation on exercise tolerance …
Cardiovascular Risk, Remote Ischemic Postconditioning, And Endothelial Ischemia-Reperfusion Injury, Brian A. Hemenway
Cardiovascular Risk, Remote Ischemic Postconditioning, And Endothelial Ischemia-Reperfusion Injury, Brian A. Hemenway
Electronic Theses and Dissertations
Remote ischemic postconditioning (rIpost) is a potent vasculoprotective stimulus that is thought to reduce reperfusion injury associated with heart disease. However, certain animal models of cardiometabolic risk factors such as dyslipidemia, diabetes, and hypertension suggest the beneficial effects of rIpost to lessen reperfusion injury may be diminished. These findings have not been studied in clinically relevant humans. The aim of this study was to determine whether the protective effects of rIpost are reduced in the context of raised cardiometabolic risk in humans. Seven participants with raised cardiometabolic risk burden (age:57±7 years; BMI: 31±4kgm2participated in this 2X2 randomized cross-over …
Influence Of Cardiovascular Risk Factors On Remote Ischemic Preconditioning, Tiffany Trachte
Influence Of Cardiovascular Risk Factors On Remote Ischemic Preconditioning, Tiffany Trachte
Electronic Theses and Dissertations
A powerful therapy against microvascular endothelial ischemia-reperfusion injury is remote ischemic preconditioning (rIPC), which triggers tissue protection by exposing a limb to small cycles of vascular occlusion. Animal models indicate that CVD risk factors reduce the protective benefits of ischemic conditioning. However, there are no human studies investigating how a burden of risk factors interferes with rIPC to prevent endothelial injury. The purpose of the present study was to determine the influence of risk factor burden on the capacity of rIPC to prevent endothelial reperfusion injury in humans. Twenty-two (age: 45±14 yr., BMI: 31±8 kg/m2) sedentary adults (12 lower burden: …
The Effect Of A Commercially Available Caffeine Based Dietary Supplement On 40-Kilometer Time Trial Performance, Lee A. Weidauer
The Effect Of A Commercially Available Caffeine Based Dietary Supplement On 40-Kilometer Time Trial Performance, Lee A. Weidauer
Electronic Theses and Dissertations
Purpose: To determine wheather ot not the nutritional supplement PreRace containing L-Taurine, Citrulline Malate, Quercetin, DiMethyl Amino Ethanol, Caffeine, Metabromine, Catechin, and Malic acid will improve performance in an indoor 40 Kilometer cycling time trial.
Methods: Seven male cyclists ages 21-58 participated in a placebo-controlled investigation which consisted of two trials in which they consumed either the supplement PreRace or aloe vera juice. In each of the trials the placebo or supplement was mixed with a sports beverage. Subjects performed a 40 kilometer time trial and measurements of oxygen consumption and lactate were taken every 15 minutes as well as …