Medicine and Health Sciences Commons^™

Feline Lentivirus: Molecular Analysis And Epidemiology In Southern African Lions, Hayley Rebecca Adams

Doctoral Dissertations

Feline immunodeficiency virus is a retrovirus of domestic cats causing significant lifelong infection. Infection has also been detected in nondomestic species, including African lions. It is endemic in certain populations in east and southern Africa. Infection leads to immunologic dysfunction and immunosuppressive disease in domestic cats; however, little research exists about the pathogenic effects of infection in lions and its epidemiological impact on free-ranging and captive populations. Little is known about the lentivirus in these populations at the molecular and host level. Analysis of the virus from these populations is necessary for development of detection assays that are both sensitive …

Justification Mechanisms In The Conditional Reasoning Test For Aggression And Their Relation To Defense Mechanisms, Cheryl Delaine Barksdale

Doctoral Dissertations

The Conditional Reasoning Test for Aggression (CRT-A; James, 1998; James & McIntyre, 2000) is an inductive reasoning test designed to assess the extent to which individuals use implicit reasoning biases – known as justification mechanisms (JMs) – to justify engaging in behavioral aggression. James and colleagues (James, 1998; James & Mazerolle, 2002; James et al., 2005) have consistently described the CRT-A as an indirect measure of these implicit cognitions, or JMs, but they recently reframed their discussion of the test to emphasize its theoretical grounding in the concept of defense mechanisms (A. Freud, 1936/1966). In particular, they indicated that the …

Nursing In Hell: The Experience Of Providing Care During And After Hurricane Katrina, Marti L. Jordan-Welch

Doctoral Dissertations

Hurricane Katrina, a Category Four hurricane, made landfall on August 29, 2005, along the Gulf Coast of Mississippi and Louisiana. The strength and the extent of winds resulted in the worst destruction and the largest storm surge in the history of the United States. Within hours after the hurricane hit, the earthen levees in New Orleans were breached and 80% of the city became submerged in up to 20 feet of water. Health care workers and patients were stranded in hospitals, where they experienced extreme environmental conditions. The death toll was reported at, 1836 persons, and the damage was estimated …

The Influence Of Level Of Training And Gender On Counseling Outcome In A University Counseling Center, Scott Andrew Sokoloski

Doctoral Dissertations

This study examined the effects of counselor level of training and gender on counseling outcome in a university counseling center environment. Data was collected from an archival database of approximately 4500 clients seen over a six-and-a-half year time period at a mid-sized Southeastern university counseling center. The Outcome Questionnaire 45.2 was used to measure client outcome, which consists of 45-items scored on a five-point Likert scale. The OQ produces three subscale scores (Symptom Distress, Interpersonal Relations, and Social Role) and a Total Score. The Social Role subscale was found to have low reliability in this study, and was omitted from …

Becoming Tied: A Theory Of Adolescent Maternal-Infant Interaction, Melinda K. Sprinkle Collins

Doctoral Dissertations

The purpose of this study was to describe the interaction that occurs between adolescent mothers and their newborns while situated together in the immediate postpartum period. The researcher sought to determine: 1) What are the interactive process (es) that occur between adolescent mothers and their newborns while situated together in the immediate postpartum period, 2) What categories emerge from the adolescents’ descriptions of the mother infant situation?, and 3) How do the emergent categories relate?

Ten primiparous adolescent mothers age 17 years or less were purposively sampled to participate in this qualitative Grounded Theory study. Face to face interviews about …

Rna Interference Of The Glycoprotein D And Dna Polymerase Genes Of Feline Herpesvirus 1 By Synthetic Sirnas, Rebecca Penrose Wilkes

Doctoral Dissertations

Feline herpesvirus 1 (FHV-1) is a linear double-stranded DNA virus that causes approximately 50% of the upper respiratory tract infections and produces the most severe respiratory disease in domestic cats. Primary ocular infection, as occurs in humans with the related virus, herpes simplex virus type 1 (HSV-1), consistently produces conjunctivitis and minimal corneal involvement; however, clinical manifestations of disease due to repeated recrudescence involve the cornea and can potentially lead to blindness. Vaccines only produce partial protection from clinical disease, and antiviral medications approved for treatment of HSV-1 in humans are only minimally effective for treatment of the chronic cases …

Examining The Ability Of The Halstead -Reitan Battery And The Wide Range Achievement Test To Utilize Severity In Discriminating Among Alzheimer's Dementia Patients, Gina Gibson-Beverly

Doctoral Dissertations

Measuring change in cognitive status is essential for the diagnosis, prognosis, and treatment of brain dysfunction. Psychological abilities are differentially affected by brain dysfunction severity, as some abilities are more vulnerable to brain dysfunction than others. Neuropsychological assessments can be viewed as a continuum of "hold" and "don't hold" tests. "Hold" tests assess abilities that remain stable in spite of brain dysfunction, while "don't hold" tests measure skills that are significantly compromised by brain impairment. The present study ranks the Halstead-Reitan Battery (HRB) and the Wide Range Achievement Test (WRAT) subtests based on their ability to discriminate between two levels …

Nonlinear Dynamical Analysis Of Brain Electrical Activity Due To Exposure To Weak Environmentally Relevant Electromagnetic Fields, Erik Alfonso Nilsen

Doctoral Dissertations

The reports dealing with the effects of weak electromagnetic fields (EMFs) on brain electrical activity have been inconsistent. We suspected that the use of linear models and their associated methods accounted for some of the variability, and we explored the issue by using a novel approach to study the effects of EMFs on the electroencephalogram (EEG) from rabbits and humans. The EEG was embedded in phase space and local recurrence plots were calculated and quantified to permit comparisons between exposed and control epochs from individual subjects. Statistically significant alterations in brain activity were observed in each subject when exposed to …

Evaluation Of A Sleep Hygiene Program To Improve Inmate Sleep Quality, Jennifer F. Hodges-Crowder

Doctoral Dissertations

Research investigating the effectiveness of treatments for inmates with poor sleep quality appears minimal. Some difficulties related to poor sleep quality can be addressed effectively with little time and expense. Studies show that psychoeducational interventions are effective in reducing sleep complaints and improving sleep quality in a variety of populations including college students and adults. However, the effect of sleep hygiene interventions on inmate sleep complaints is unknown. Thus, the purpose of this study was to evaluate a psychoeducational intervention program aimed at improving prison inmate sleep habits, length, and quality.

Participants of this study were inmates at a department …

Female Faculty Experiences Of Discrimination In Higher Education, Kylie Gray Cole

Doctoral Dissertations

The primary purpose of this study was to obtain a description of women faculty members’ experiences of discrimination in higher education. The phenomenological research methodology informed the study. Seventeen participants were asked to respond to the question, “Can you tell me about your experience of discrimination as a faculty member in a higher education institution?” The interviews were in-depth and unstructured. Verbatim transcripts of the audio-taped interviews were completed and a phenomenological research group analyzed the data using the phenomenological method. Two grounds and three main themes emerged from the data. The first ground was Minimize/Describe Discrimination. This captured the …

Characterization And Comparative Analysis Of Gene Expression Profiles Of Three Different Human Oral Squamous Carcinoma Cell Lines With Different Invasion And Metastatic Capacities, Necip Fazil Erdem

Doctoral Dissertations

Matrix metalloproteinases (MMP’s) and cathepsins are thought to play key roles in oral squamous cell carcinoma (OSCC) invasion and metastasis. Three OSCC human cell lines, BHY, HN and HSC-3, have been studied based on their reported ability to invade adjacent bone or metastasize to lymph nodes and/or distant organs. The working hypothesis of this study is that OSCC that demonstrate different actions have different proteolytic enzyme and gene expression profiles.

Immunocytochemistry and flow cytometry were used to determine the expression levels of certain proteolytic enzymes. Complementary DNA (cDNA) microarray technique was used to determine the gene expression profiles of each …

Waiting For The Other Shoe To Drop: The Lived Experience Of Hope For Mothers Of Premature Infants In The Neonatal Intensive Care Unit, Kristina Maria Plaas

Doctoral Dissertations

The purpose of this study was to describe the lived experience of hope for mothers of premature infants in the Neonatal Intensive Care Unit (NICU). This study was grounded in the existential-phenomenologic philosophy of Merleau-Ponty. A purposive sample of six mothers of infants born between 23 ½ and 31 weeks gestation were interviewed by the researcher 10 months to 2 ½ years after birth. Mothers were asked to think back to when their infant was in the NICU and tell about a specific time when they were aware of hope. Interviews were transcribed verbatim and analyzed following a hermeneutic process …

The Dose-Response Association Of Physical Activity And The Metabolic Syndrome Among U.S. Adults: Nhanes 1999-2004, James R. Churilla

Doctoral Dissertations

The purpose of this study was to evaluate the current prevalence of the metabolic syndrome with an emphasis on examining the relationship between leisure time physical activity (LTPA) and the metabolic syndrome in a nationally representative sample of the United States (U.S.) adult population within the 1999-2004 National Health and Nutrition Examination Survey (NHANES). The sample for this study included adults (N=5620), 20 years and older, who attended a mobile examination center (MEC) examination in the NHANES 1999-2004. The American Heart Association and National Heart, Lung, and Blood Institute (AHA/NHLBI) AHA/NHLBI definition was used to define the metabolic syndrome based …

Why Am I Still Here, You Ask? A Phenomenological Study Of The Lived Experience Of Nurse Managers, Wendy Carlton Shea-Messler

Doctoral Dissertations

Fewer people are entering the profession of nursing. There is already a shortage of nurses, yet, many abandon the bedside for lucrative ways to practice their art and for respected positions less inhibited by bureaucratic initiatives. A significant percentage of nurses will soon retire, further diminishing the number of experienced caregivers.

Good nurses require great leaders. A primary goal of organizations is to retain and recruit effective nurse managers. This study provides insight to the needs of nurse managers and aspects that keep them from leaving their jobs. The purpose of this study was to gain a differentiated understanding of …

Classroom Acoustics And Intervention Strategies To Enhance The Learning Environment, Christal Savage

Doctoral Dissertations

The classroom environment can be an acoustically difficult atmosphere for students to learn effectively, sometimes due in part to poor acoustical properties. Noise and reverberation have a substantial influence on room acoustics and subsequently intelligibility of speech. The American Speech-Language-Hearing Association (ASHA, 1995) developed minimal standards for noise and reverberation in a classroom for the purpose of providing an adequate listening environment. A lack of adherence to these standards may have undesirable consequences, which may lead to poor academic performance.

The purpose of this capstone project is to develop a protocol to measure the acoustical properties of reverberation time and …

A Protocol For Sound Localization Testing With Young And Aging Normal Hearing Subjects, Alison V. Huff

Doctoral Dissertations

An important aspect of processing auditory stimulus is the ability to localize the source of a sound within the environment. Localization has been defined as the ability to determine the direction of sound (Tonning, 1975; Cranford, Boose, & Moore, 1990; Middlebrooks & Green, 1991; Cranford Andres, Piatz, & Reissig, 1993; Lorenzi Gatehouse, & Lever, 1999; Abel, Giguere, Consoli, & Papsin, 2000). Previous researchers have used a variety of test stimuli, test environments, loudspeaker arrays, and ages and numbers of subjects to measure the ability to localize sounds. Despite the obvious need for individuals to identify the specific location of a …

Sound Localization Accuracy In The Blind Population, Mary Arrington Deloach

Doctoral Dissertations

The ability to accurately locate a sound source is crucial in the blind population to orient and mobilize independently in the environment. Sound localization is accomplished by the detection of binaural differences in intensity and time of incoming sound waves along with phase differences and spectral cues. It is dependent on auditory sensitivity and processing. However, localization ability can not be predicted from the audiogram or an auditory processing evaluation.

Auditory information is not received only from objects making sound, but also from objects reflecting sound. Auditory information used in this manner is called echolocation. Echolocation significantly enhances localization in …

A Communication Process Training Model For Use By Audiologists In Counseling, Heather Hendrix

Doctoral Dissertations

Audiologists must assume the role of a counselor when providing interpretation of test results to patients and/or family members. A successful audiologist will rely on the knowledge of auditory disorders and rehabilitation and will be willing to form an effective relationship with the patient through communicative counseling. The purpose of this capstone project is to develop a training protocol for audiologists based on a communication process model. This capstone project discusses the process of designing counseling training sessions.

The basic principles of the Adler and Elmhorst (2002) communication process model were used to develop a dialogue and scenarios (role-playing activity) …

Parental Views Of Otitis Media And Antibiotic Treatment, Courtney Leigh Ross

Doctoral Dissertations

Antibiotic resistance is a rapidly growing problem throughout the world. Antibiotic resistance can be due to a number of factors, including unnecessary antibiotic prescriptions, antibiotic misuse, and transmission of resistant bacteria.

Otitis media is the most often diagnosed childhood illness and accounts for the majority of the United States' annual antibiotic prescriptions. Both parents and physicians can contribute to unnecessary antibiotic treatment for otitis media. Understanding parental views of otitis media and antibiotic treatment may help reduce unnecessary antibiotic prescriptions and lead to the subsequent reduction in antibiotic resistance.

The purpose of this capstone project is to develop a questionnaire …