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Studies Related To The Structure And Mechanism Of Action Of Rabbit Muscle Aldolase, Christian F. Midelfort
Studies Related To The Structure And Mechanism Of Action Of Rabbit Muscle Aldolase, Christian F. Midelfort
Dissertations (1934 -)
This dissertation deals with several aspects of the structure and catalytic functions of the enzyme fructose - 1,6-diphosphate aldolase (I.U.B. Number 4.1.2.13) isolated from rabbit muscle.
First, it concerns the chemical nature of the proteolytic modifications of aldolase by a-chymotrypsin and subtilopeptidase B (Novo) in producing an enzyme with catalytic properties like those of the aldolase modified by carboxypeptidase A. The a-chymotrypsin modification has been published (C.F. Midelfort and A.H. Mehler, J. Biol. Chem. 247. 3127 (1972)).
Second it presents evidence for the occurrence of a slow deamidation of an asparagine residue in muscle aldolase in vivo which results in …