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Medicine and Health Sciences Commons

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Department of Surgery

Lehigh Valley Health Network

2021

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Full-Text Articles in Medicine and Health Sciences

Use Of Botulinum Toxin A To Treat Chemotherapy-Induced Raynaud's Phenomenon., Thrisha K Potluri, Frank G Lee, Ethan Song, Sean J. Wallace Md, Nathan F. Miller Md Jan 2021

Use Of Botulinum Toxin A To Treat Chemotherapy-Induced Raynaud's Phenomenon., Thrisha K Potluri, Frank G Lee, Ethan Song, Sean J. Wallace Md, Nathan F. Miller Md

Department of Surgery

Raynaud's phenomenon (RP) is a vasospastic disorder of the digital blood vessels leading to pain, paresthesias, and pallor in response to cold or stress. RP can develop secondary to a number of pathologies or factors, including the use of chemotherapy agents. Typical first-line therapies for secondary RP may be contraindicated in patients with certain comorbidities. Here, we discuss a case in which botulinum toxin A (BTX-A) was used to treat chemotherapy-induced RP in a patient with non-small cell lung cancer (NSCLC). We provide a review of the existing literature on the clinical course and treatment modalities, including the use of …