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Medicine and Health Sciences Commons

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Department of Medicine

2007

Bleomycin ; pneumonitis; steroids.

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Full-Text Articles in Medicine and Health Sciences

Bleomycin Induced Pneumonitis: A Case Successfully Managed With High-Dose Steroids., Shahid Javed Husain, Ali Bin Sarwar Zubairi, Muhammad Irfan Feb 2007

Bleomycin Induced Pneumonitis: A Case Successfully Managed With High-Dose Steroids., Shahid Javed Husain, Ali Bin Sarwar Zubairi, Muhammad Irfan

Department of Medicine

Bleomycin is a chemotherapeutic agent used in a number of solid organ malignancies.1-3 It accumulates in the skin and lungs resulting in skin ulceration and associated pulmonary toxicity. Its use is somewhat limited due to its significant pulmonary adverse effects with bleomycin induced pnemonitis (BIP) as the commonest and most dreaded complications. The overall incidence of pulmonary toxicity is as high as 10% and it is fatal in 1-2%.3,4 We present a case of BIP which was successfully managed by the aggressive use of high dose steroids with complete resolution.